Page last updated: 2024-08-18

quinuclidines and Sjogren's Syndrome

quinuclidines has been researched along with Sjogren's Syndrome in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.65)18.2507
2000's29 (67.44)29.6817
2010's10 (23.26)24.3611
2020's2 (4.65)2.80

Authors

AuthorsStudies
Acquarulo, B; Macica, CM; Tandon, P1
Isola, M; Isola, R; Loy, F; Masala, C1
Asbell, PA; Kuklinski, E1
B E, S; Badam, RK; Boringi, M; Garlapati, K; Kammari, A; Soni, P1
Chen, CH; Chou, YC; Huang, WY; Ju, UH; Kao, CH; Lin, CL; Lin, CS; Lin, KT; Lin, TY; Liu, FC; Shen, CH; Yang, TY1
Chimenos Küstner, E; Jané Salas, E; López-López, J1
Kusukawa, J; Nakamura, M; Saga, T; Tabira, Y; Takahashi, N; Watanabe, K; Yamaki, K1
Davis, RM; Grubbs, J; Huynh, K; Liu, KC1
Matera, C; Tata, AM1
Kawakami, A; Nakamura, H; Nakamura, T; Sato, S; Sumi, M; Takagi, Y1
Keating, GM; Weber, J1
Katayama, I; Nakamura, T; Takagi, Y; Tashiro, S1
Hashiramoto, A; Komai, K; Murata, M; Sakai, H; Shiozawa, K; Shiozawa, S; Tanaka, C; Tanaka, Y; Tsumiyama, K; Yamane, T; Yoshihara, R1
Ishikawa, Y; Iwata, F; Mori, T; Muraguchi, M; Ohmoto, Y; Ooga, K; Takai, M; Wang, D1
Nishimura, H; Saga, T; Yakeishi, A; Yamaki, K1
Goto, D; Hayashi, T; Iizuka, M; Ito, S; Matsumoto, I; Nakamura, Y; Sumida, T; Tsuboi, H; Wakamatsu, E1
Adyanthaya, RS; Akpek, EK; Baer, AN; Lindsley, KB; McDonnell, PJ; Swamy, R1
Shiozawa, A1
Fox, RI1
Kimura, Y; Nakamura, T; Takagi, Y1
Hanzawa, M; Iikuni, N; Nishinarita, M; Ota, S1
Hamano, T; Ono, M; Shinozaki, K; Takamura, E; Tsubota, K; Tsumura, T; Yagi, Y1
Fukushima, T; Hirose, Y; Karasawa, H; Masaki, Y; Ogawa, N; Shimoyama, K; Sugai, S; Wano, Y1
Matsumoto, M; Nakanishi, T; Nakashima, M; Ohsuzu, F; Okada, M; Suzuki, K; Takada, K1
Atkinson, JC; Grisius, M; Massey, W1
Chu, DS; Kapila, R; Wladis, EJ1
Al-Hashimi, I1
Mishima, K; Nakagawa, Y; Nomura, Y; Saito, I; Sumida, T; Wakamatsu, E; Yamachika, S; Yamada, H1
Gause, A1
Brennan, MT; Carrozzo, M; Daniels, T; Fox, PC; Fujibayashi, T; Gandera, B; Jonsson, R; Lockhart, PB; Navazesh, M; Rhodus, NL; Schiødt, M; Sollecito, TP; von Bültzingslöwen, I; Wray, D1
Lau, CS; Leung, KC; Leung, WK; McMillan, AS; Mok, MY; Wong, MC1
Iwabuchi, Y; Masuhara, T1
Anaya, JM; Talal, N1
Fox, RI; Michelson, P1
al-Hashimi, I; Taylor, SE1
Atkinson, JC; Baum, BJ1
Fisher, A; Fox, RI; Konttinen, Y1
Arisawa, H; Fujise, N; Fukui, K; Imai, E; Masunaga, H2
Arisawa, H; Fujise, N; Fukui, K; Masunaga, H1
Cohen, S; Condemi, JJ; Dalgin, P; Fife, R; Gluck, O; Petrone, D1
Arisawa, H; Fukui, K; Masunaga, H1
Chase, WF; Dore, RK; Fife, RS; Lockhart, PB; Suen, JY; Tindall, E; Wiesenhutter, CW1

Reviews

14 review(s) available for quinuclidines and Sjogren's Syndrome

ArticleYear
Sjogren's syndrome from the perspective of ophthalmology.
    Clinical immunology (Orlando, Fla.), 2017, Volume: 182

    Topics: Administration, Ophthalmic; Cyclosporine; Dry Eye Syndromes; Fatty Acids, Omega-3; Glucocorticoids; Humans; Immunosuppressive Agents; Lubricant Eye Drops; Muscarinic Agonists; Ophthalmology; Phenylalanine; Pilocarpine; Punctal Plugs; Quinuclidines; Sjogren's Syndrome; Sulfones; Thiophenes

2017
Meta-analysis on pharmacological therapies in the management of xerostomia in patients with Sjogren's syndrome.
    Immunopharmacology and immunotoxicology, 2019, Volume: 41, Issue:2

    Topics: Female; Humans; Interferon-alpha; Male; Pilocarpine; Quinuclidines; Saliva; Sjogren's Syndrome; Thiophenes

2019
[Prognosis and treatment of dry mouth. Systematic review].
    Medicina clinica, 2014, Feb-04, Volume: 142, Issue:3

    Topics: Cholinergic Antagonists; Clinical Trials as Topic; Dental Caries; Disease Susceptibility; Double-Blind Method; Fluid Therapy; Humans; Meta-Analysis as Topic; Mouthwashes; Observational Studies as Topic; Pilocarpine; Prognosis; Quinuclidines; Radiation Injuries; Radiotherapy; Saliva, Artificial; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia

2014
Autoimmunity in the pathogenesis and treatment of keratoconjunctivitis sicca.
    Current allergy and asthma reports, 2014, Volume: 14, Issue:1

    Topics: Animals; Antigen-Presenting Cells; Apoptosis; Autoantibodies; Autoimmunity; Cyclosporine; Genetic Predisposition to Disease; Humans; Immunity, Cellular; Immunity, Humoral; Keratoconjunctivitis Sicca; Molecular Mimicry; Quinuclidines; Sjogren's Syndrome; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thiophenes

2014
Pharmacological approaches to targeting muscarinic acetylcholine receptors.
    Recent patents on CNS drug discovery, 2014, Volume: 9, Issue:2

    Topics: Alzheimer Disease; Animals; Humans; Muscarinic Agonists; Pyridines; Quinuclidines; Receptors, Muscarinic; Sjogren's Syndrome; Thiadiazoles; Thiophenes

2014
Treatment of Sjögren's syndrome-associated dry eye an evidence-based review.
    Ophthalmology, 2011, Volume: 118, Issue:7

    Topics: Administration, Oral; Administration, Topical; Anti-Inflammatory Agents; Dry Eye Syndromes; Evidence-Based Medicine; Humans; Hydroxychloroquine; Immunosuppressive Agents; Lubricants; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes

2011
[Cevimeline hydrochloride hydrate (Saligren capsule 30 mg): a review of its pharmacological profiles and clinical potential in xerostomia].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2002, Volume: 120, Issue:4

    Topics: Adult; Animals; Humans; Male; Muscarinic Agonists; Quinuclidines; Sjogren's Syndrome; Thiophenes

2002
Use of cevimeline, a muscarinic M1 and M3 agonist, in the treatment of Sjögren's syndrome.
    Advances in experimental medicine and biology, 2002, Volume: 506, Issue:Pt B

    Topics: Humans; Muscarinic Agonists; Quinuclidines; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic; Sjogren's Syndrome; Thiophenes

2002
Salivary hypofunction and xerostomia: diagnosis and treatment.
    Dental clinics of North America, 2005, Volume: 49, Issue:2

    Topics: Aged; Aged, 80 and over; Cariostatic Agents; Fluorides; Humans; Pilocarpine; Polypharmacy; Quinuclidines; Radiotherapy; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia

2005
Xerostomia secondary to Sjögren's syndrome in the elderly: recognition and management.
    Drugs & aging, 2005, Volume: 22, Issue:11

    Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia

2005
Salivary dysfunction associated with systemic diseases: systematic review and clinical management recommendations.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103 Suppl

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents; Diabetes Complications; HIV Infections; Humans; Interferon-alpha; Muscarinic Agonists; Pilocarpine; Quinuclidines; Rituximab; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia

2007
Sjögren's syndrome comes of age.
    Seminars in arthritis and rheumatism, 1999, Volume: 28, Issue:6

    Topics: Apoptosis; Humans; Lymphocytosis; Muscarinic Agonists; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Salivary Glands; Sjogren's Syndrome; Thiophenes

1999
Approaches to the treatment of Sjögren's syndrome.
    The Journal of rheumatology. Supplement, 2000, Volume: 61

    Topics: Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes

2000
Use of muscarinic agonists in the treatment of Sjögren's syndrome.
    Clinical immunology (Orlando, Fla.), 2001, Volume: 101, Issue:3

    Topics: Humans; Muscarinic Agonists; Neuroimmunomodulation; Neurosecretory Systems; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Sjogren's Syndrome; Thiophenes

2001

Trials

8 trial(s) available for quinuclidines and Sjogren's Syndrome

ArticleYear
Parotid irrigation and cevimeline gargle for treatment of xerostomia in Sjögren's syndrome.
    The Journal of rheumatology, 2008, Volume: 35, Issue:11

    Topics: Humans; Mouthwashes; Parasympathomimetics; Parotid Gland; Quinuclidines; Sjogren's Syndrome; Steroids; Therapeutic Irrigation; Thiophenes; Xerostomia

2008
Therapeutic effect of cevimeline on dry eye in patients with Sjögren's syndrome: a randomized, double-blind clinical study.
    American journal of ophthalmology, 2004, Volume: 138, Issue:1

    Topics: Conjunctiva; Double-Blind Method; Epithelial Cells; Epithelium, Corneal; Female; Fluorophotometry; Humans; Male; Middle Aged; Muscarinic Agonists; Patient Compliance; Prospective Studies; Quinuclidines; Rose Bengal; Safety; Sjogren's Syndrome; Tears; Thiophenes; Treatment Outcome

2004
Effect of cevimeline on salivary components in patients with Sjögren syndrome.
    Pharmacology, 2005, Volume: 74, Issue:2

    Topics: alpha-Amylases; Antigens, Neoplasm; Female; Humans; Immunoglobulin A; Middle Aged; Muramidase; Muscarinic Agonists; Quinuclidines; Saliva; Salivation; Serpins; Sjogren's Syndrome; Thiophenes; Xerostomia

2005
Efficacy prediction of cevimeline in patients with Sjögren's syndrome.
    Clinical rheumatology, 2007, Volume: 26, Issue:8

    Topics: Adult; Aged; Female; Humans; Middle Aged; Parasympathomimetics; Parotid Gland; Prognosis; Quinuclidines; Receptors, Muscarinic; Salivation; Sialography; Sjogren's Syndrome; Thiophenes; Treatment Outcome; Xerostomia

2007
The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sjögren's syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study.
    Clinical rheumatology, 2008, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; China; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Health Surveys; Humans; Middle Aged; Muscarinic Agonists; Oral Health; Patient Satisfaction; Quality of Life; Quinuclidines; Severity of Illness Index; Sjogren's Syndrome; Thiophenes; Xerostomia

2008
A double-blind, randomized, placebo-controlled study of cevimeline in Sjögren's syndrome patients with xerostomia and keratoconjunctivitis sicca.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:3

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Keratoconjunctivitis Sicca; Male; Middle Aged; Muscarinic Agonists; Placebos; Quinuclidines; Safety; Saliva; Sjogren's Syndrome; Tears; Thiophenes; Xerostomia

2002
Cevimeline for the treatment of xerostomia in patients with Sjögren syndrome: a randomized trial.
    Archives of internal medicine, 2002, Jun-10, Volume: 162, Issue:11

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia

2002
General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sjögren's syndrome. 4th communication: Effects on gastrointestinal, urinary and reproductive systems and other effects.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cardiovascular System; Cross-Over Studies; Digestive System; Dogs; Female; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Pregnancy; Quinuclidines; Rabbits; Rats; Rats, Wistar; Reproduction; Sjogren's Syndrome; Thiophenes; Urogenital System; Xerostomia

2002

Other Studies

21 other study(ies) available for quinuclidines and Sjogren's Syndrome

ArticleYear
Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report.
    Journal of medical case reports, 2022, Jun-29, Volume: 16, Issue:1

    Topics: Bacopa; Cholinergic Agents; Cytochrome P-450 Enzyme System; Female; Humans; Middle Aged; Quinuclidines; Sjogren's Syndrome; Thiophenes

2022
Reactivity of human labial glands in response to cevimeline treatment.
    Anatomical record (Hoboken, N.J. : 2007), 2021, Volume: 304, Issue:12

    Topics: Carbachol; Humans; Lip; Quinuclidines; Salivary Glands; Sjogren's Syndrome; Thiophenes

2021
Risk of Parkinson disease in Sjögren syndrome administered ineffective immunosuppressant therapies: A nationwide population-based study.
    Medicine, 2019, Volume: 98, Issue:14

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Comorbidity; Female; Humans; Hydroxychloroquine; Immunosuppression Therapy; Incidence; Male; Methylprednisolone; Middle Aged; Muscarinic Agonists; National Health Programs; Parkinson Disease; Pilocarpine; Quinuclidines; Retrospective Studies; Risk Factors; Sjogren's Syndrome; Taiwan; Thiophenes

2019
An immunohistochemistry-based study on aquaporin (AQP)-1, 3, 4, 5 and 8 in the parotid glands, submandibular glands and sublingual glands of Sjögren's syndrome mouse models chronically administered cevimeline.
    The Kurume medical journal, 2013, Volume: 60, Issue:1

    Topics: Animals; Aquaporin 1; Aquaporin 3; Aquaporin 4; Aquaporin 5; Aquaporins; Disease Models, Animal; Immunohistochemistry; Mice; Muscarinic Agonists; Parotid Gland; Quinuclidines; Salivation; Sjogren's Syndrome; Sublingual Gland; Submandibular Gland; Thiophenes; Time Factors

2013
Salivary gland ultrasonography as a primary imaging tool for predicting efficacy of xerostomia treatment in patients with Sjögren's syndrome.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:2

    Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glucocorticoids; Humans; Male; Middle Aged; Muscarinic Agonists; Parasympathomimetics; Pilocarpine; Prednisolone; Prognosis; Quinuclidines; Retrospective Studies; Salivary Glands; Severity of Illness Index; Sjogren's Syndrome; Therapeutic Irrigation; Thiophenes; Treatment Outcome; Ultrasonography; Xerostomia

2016
Cevimeline.
    Drugs, 2008, Volume: 68, Issue:12

    Topics: Animals; Area Under Curve; Diarrhea; Female; Half-Life; Humans; Molecular Structure; Muscarinic Agonists; Nausea; Quinuclidines; Randomized Controlled Trials as Topic; Rhinitis; Sjogren's Syndrome; Sweating; Thiophenes; Treatment Outcome

2008
Sjögren's syndrome patients presenting with hypergammaglobulinemia are relatively unresponsive to cevimeline treatment.
    Modern rheumatology, 2009, Volume: 19, Issue:4

    Topics: Bodily Secretions; Diagnosis, Differential; Drug Resistance; Humans; Hypergammaglobulinemia; Middle Aged; Muscarinic Agonists; Quinuclidines; Saliva; Sjogren's Syndrome; Thiophenes; Xerostomia

2009
Correlation between salivary secretion and salivary AQP5 levels in health and disease.
    The journal of medical investigation : JMI, 2009, Volume: 56 Suppl

    Topics: Aquaporin 5; Diabetes Mellitus, Type 1; Humans; Membrane Microdomains; Muscarinic Agonists; Quinuclidines; Receptor, Muscarinic M3; Saliva; Salivary Glands; Salivation; Sjogren's Syndrome; Thiophenes

2009
Effects of cevimeline on the immunolocalization of aquaporin-5 and the ultrastructure of salivary glands in Sjögren's syndrome model mice.
    The Kurume medical journal, 2009, Volume: 56, Issue:3-4

    Topics: Animals; Aquaporin 5; Disease Models, Animal; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Microscopy, Electron; Muscarinic Agonists; Quinuclidines; Sjogren's Syndrome; Submandibular Gland; Thiophenes

2009
New epitopes and function of anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjögren's syndrome.
    Clinical and experimental immunology, 2010, Volume: 162, Issue:1

    Topics: Adult; Aged; Amino Acid Sequence; Antibodies, Anti-Idiotypic; Calcium; Cells, Cultured; Epitopes; Epitopes, B-Lymphocyte; Female; Fluorescent Antibody Technique; Gene Expression; Humans; Intracellular Space; Male; Middle Aged; Molecular Sequence Data; Muscarinic Agonists; Peptides; Quinuclidines; Receptor, Muscarinic M3; Reverse Transcriptase Polymerase Chain Reaction; Salivary Glands; Sjogren's Syndrome; Thiophenes

2010
Cevimeline gargle for the treatment of xerostomia in patients with Sjögren's syndrome.
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:6

    Topics: Administration, Oral; Adult; Aged; Female; Humans; Male; Middle Aged; Mouthwashes; Parasympathomimetics; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia

2004
[The effectiveness of cevimeline hydrochloride on dry cough in Sjögren's syndrome].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2004, Volume: 27, Issue:2

    Topics: Adult; Aged; Cough; Dry Eye Syndromes; Female; Humans; Male; Middle Aged; Muscarinic Agonists; Quinuclidines; Sjogren's Syndrome; Thiophenes

2004
[Clinical significance of cevimeline hydrochloride in the treatment of dry mouth in patients with Sjögren's syndrome].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2004, Volume: 27, Issue:5

    Topics: Female; Humans; Middle Aged; Muscarinic Agonists; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia

2004
Idiopathic CD4+ lymphocytopenia and Sjogren syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:7

    Topics: CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; Humans; Middle Aged; Muscarinic Agonists; Quinuclidines; Sjogren's Syndrome; T-Lymphocytopenia, Idiopathic CD4-Positive; Thiophenes

2005
[Revision of the recommendations of the Commission on Pharmacotherapy of the German Society for Rheumatology. Recommendations for supportive therapy for Sjögren's syndrome].
    Zeitschrift fur Rheumatologie, 2007, Volume: 66, Issue:1

    Topics: Bromhexine; Cyclosporine; Dry Eye Syndromes; Electric Stimulation Therapy; Expectorants; Humans; Muscarinic Antagonists; Ophthalmic Solutions; Pilocarpine; Quinuclidines; Sjogren's Syndrome; Thiophenes; Xerostomia

2007
Sialogogic activities of SNI-2011 compared with those of pilocarpine and McN-A-343 in rat salivary glands: identification of a potential therapeutic agent for treatment of Sjörgen's syndrome.
    General pharmacology, 1994, Volume: 25, Issue:1

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenergic Antagonists; Animals; Cholinergic Antagonists; Male; Pilocarpine; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Salivary Glands; Salivation; Sjogren's Syndrome; Thiophenes

1994
A new medication for treatment of dry mouth in Sjögren's syndrome.
    Texas dental journal, 2001, Volume: 118, Issue:3

    Topics: Contraindications; Humans; Muscarinic Agonists; Pilocarpine; Quinuclidines; Receptors, Muscarinic; Salivary Glands; Salivation; Sjogren's Syndrome; Thiophenes; Xerostomia

2001
Salivary enhancement: current status and future therapies.
    Journal of dental education, 2001, Volume: 65, Issue:10

    Topics: Animals; Aquaporin 1; Aquaporins; Blood Group Antigens; Cholinergic Agents; Cranial Irradiation; Dental Caries; Genetic Therapy; Humans; Parasympathomimetics; Pilocarpine; Quinuclidines; Salivary Glands; Sjogren's Syndrome; Thiophenes; Xerostomia

2001
General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sjögren's syndrome. 1st communication: effects on general behavior and central nervous system.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Anticonvulsants; Behavior, Animal; Body Temperature; Cats; Central Nervous System; Electroencephalography; Electroshock; Female; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscarinic Agonists; Pain Measurement; Psychomotor Performance; Quinuclidines; Rats; Rats, Wistar; Reflex; Sjogren's Syndrome; Thiopental; Thiophenes; Xerostomia

2002
General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sjögren's syndrome. 2nd communication: effects on somatic nervous system and on autonomic nervous system and smooth muscle.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:2

    Topics: Anesthetics; Animals; Autonomic Nervous System; Catecholamines; Cats; Guinea Pigs; Histamine Antagonists; Male; Mice; Mice, Inbred ICR; Muscarinic Agonists; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Muscle, Smooth, Vascular; Neuromuscular Junction; Nictitating Membrane; Peripheral Nervous System; Pupil; Quinuclidines; Rabbits; Rats; Rats, Inbred F344; Rats, Wistar; Sjogren's Syndrome; Thiophenes; Xerostomia

2002
General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sjögren's syndrome. 3rd communication: effects on respiratory and cardiovascular systems.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:3

    Topics: Animals; Atropine; Dogs; Electrocardiography; Guinea Pigs; Heart Atria; Hemodynamics; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; Quinuclidines; Regional Blood Flow; Respiratory Mechanics; Sjogren's Syndrome; Thiophenes; Xerostomia

2002