quinuclidines has been researched along with Schizophrenia in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dineley, KT; Dunphy, JM; Haydon, PG; Papouin, T; Tolman, M | 1 |
| Cao, D; Kang, B; Meng, Y; Ning, H; Wang, H; Xie, S | 1 |
| Bauer, LO; Dgetluck, N; Gawryl, M; Hilt, DC; Palfreyman, M; Preskorn, SH | 1 |
| Parachikova, AI; Pedersen, CS; Plath, N; Sørensen, DB | 1 |
| Kohlhaas, KL; Robb, HM; Roderwald, VA; Rueter, LE | 1 |
| Hashimoto, K | 1 |
| Beaver, JS; Dunbar, GC; Dvergsten, C; Fleischhacker, WW; Hosford, DA; Jett, JE; Kane, J; Keefe, RS; Marder, SR; Segreti, AC; Toler, SM; Walling, D | 1 |
| Dgetluck, N; Gawryl, M; Hilt, DC; Keefe, RS; Koenig, G; Lombardo, I; Meltzer, HA; Moebius, HJ | 1 |
| Bain, EE; Baker, JD; Haig, GM; Othman, AA; Robieson, WZ | 1 |
| Haig, G; Othman, AA; Wang, D; Zhao, J | 1 |
| Benitex, Y; Bristow, LJ; Chen, P; Cook, J; Daly, C; Easton, AE; Gallagher, L; Hendricson, A; Iwuagwu, C; Jones, KM; King, D; Li, YW; Lidge, R; Lodge, NJ; Macor, JE; Molski, T; Morgan, D; Olson, R; Pieschl, R; Post-Munson, D; Sivarao, DV; Westphal, R; Zaczek, R | 1 |
| Bencherif, M; Gatto, GJ; Hauser, TA; Hesse, RA; Jordan, KG; Kucinski, A; Lippiello, PM; Papke, RL; Stachowiak, EK; Stachowiak, MK; Wersinger, SR | 1 |
| Bencherif, M; Kucinski, A; Stachowiak, EK; Stachowiak, MK; Syposs, C; Wersinger, S | 1 |
| Beaver, JS; Duan, N; Dunbar, G; Girgis, RR; Hosford, DA; Lieberman, JA; Segreti, AC; Seoane, F | 1 |
| LEVIT, VG; SMULEVICH, AB | 1 |
| Arneric, SP; Carey, G; Cook, KK; Cortes-Burgos, LA; Franklin, S; Gold, LH; Groppi, VE; Hajos, M; Hanchar, AJ; Higdon, NR; Hoffmann, WE; Hurst, RS; Jacobsen, EJ; Jia, S; Kalgutkar, AS; Myers, JK; Olson, KL; Raub, TJ; Reitz, SC; Rogers, BN; Sands, SB; Soglia, JR; Staton, BA; Thornburgh, BA; Walker, DP; Wall, TM; Walters, RR; Wishka, DG; Wolfe, ML; Wong, EH; Yates, KM; Zhao, SX | 1 |
| Bennett, JP; Bylund, DB; Enna, SJ; Gillin, JC; Snyder, SH; Wyatt, RJ | 1 |
| Balashova, LN; Gromova, VV | 1 |
1 review(s) available for quinuclidines and Schizophrenia
| Article | Year |
|---|---|
Targeting of α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia and the Use of Auditory Sensory Gating as a Translational Biomarker.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Benzylidene Compounds; Biomarkers; Evoked Potentials, Auditory; Humans; Pyridines; Quinuclidines; Schizophrenia; Sensory Gating; Thiadiazoles | 2015 |
6 trial(s) available for quinuclidines and Schizophrenia
| Article | Year |
|---|---|
Normalizing effects of EVP-6124, an α-7 nicotinic partial agonist, on event-related potentials and cognition: a proof of concept, randomized trial in patients with schizophrenia.
Topics: Adolescent; Adult; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Cognition; Cognition Disorders; Double-Blind Method; Drug Therapy, Combination; Evoked Potentials; Female; Humans; Male; Middle Aged; Quinuclidines; Schizophrenia; Thiophenes; Treatment Outcome; Young Adult | 2014 |
Phase 2 Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) in Negative and Cognitive Symptoms of Schizophrenia.
Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Benzofurans; Female; Humans; Male; Middle Aged; Nicotinic Agonists; Outcome Assessment, Health Care; Quinuclidines; Schizophrenia; Severity of Illness Index; Young Adult | 2016 |
Randomized, Double-Blind, Placebo-Controlled Study of Encenicline, an α7 Nicotinic Acetylcholine Receptor Agonist, as a Treatment for Cognitive Impairment in Schizophrenia.
Topics: Adolescent; Adult; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Cognition; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Nicotinic Agonists; Psychiatric Status Rating Scales; Psychotropic Drugs; Quinuclidines; Schizophrenia; Schizophrenic Psychology; Thiophenes; Treatment Outcome; Young Adult | 2015 |
A Randomized Trial to Assess the Efficacy and Safety of ABT-126, a Selective α7 Nicotinic Acetylcholine Receptor Agonist, in the Treatment of Cognitive Impairment in Schizophrenia.
Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Attention; Cognitive Dysfunction; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Nootropic Agents; Psychometrics; Quinuclidines; Schizophrenia; Schizophrenic Psychology; Smoking; Thiadiazoles; Treatment Outcome; Verbal Learning | 2016 |
The α7 Nicotinic Agonist ABT-126 in the Treatment of Cognitive Impairment Associated with Schizophrenia in Nonsmokers: Results from a Randomized Controlled Phase 2b Study.
Topics: Adult; Aged; Cognition Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Neuropsychological Tests; Nicotinic Agonists; Quinuclidines; Schizophrenia; Schizophrenic Psychology; Thiadiazoles; Treatment Outcome; Young Adult | 2016 |
A randomized exploratory trial of an α-7 nicotinic receptor agonist (TC-5619) for cognitive enhancement in schizophrenia.
Topics: Adolescent; Adult; alpha7 Nicotinic Acetylcholine Receptor; Antipsychotic Agents; Benzofurans; Female; Humans; India; Male; Middle Aged; Nicotinic Agonists; Nootropic Agents; Quinuclidines; Schizophrenia; Schizophrenic Psychology; United States; Young Adult | 2013 |
11 other study(ies) available for quinuclidines and Schizophrenia
| Article | Year |
|---|---|
Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Behavior, Animal; Chromatography, High Pressure Liquid; Conditioning, Psychological; Electroencephalography; Electromyography; Excitatory Postsynaptic Potentials; Fear; Hippocampus; Immunohistochemistry; Learning; Memory; Mice; Mice, Transgenic; Microdialysis; Neck Muscles; Nicotinic Agonists; Optical Imaging; Optogenetics; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine; Synapses; Thiophenes; Wakefulness | 2017 |
Effects of haloperidol, olanzapine, ziprasidone, and PHA-543613 on spatial learning and memory in the Morris water maze test in naïve and MK-801-treated mice.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Haloperidol; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Olanzapine; Piperazines; Quinuclidines; Schizophrenia; Spatial Learning; Thiazoles; Treatment Outcome | 2017 |
PCP-induced deficits in murine nest building activity: employment of an ethological rodent behavior to mimic negative-like symptoms of schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzofurans; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Phencyclidine; Quinuclidines; Rotarod Performance Test; Schizophrenia; Schizophrenic Psychology; Social Behavior; Thiophenes | 2014 |
Nicotinic modulation of auditory evoked potential electroencephalography in a rodent neurodevelopmental model of schizophrenia.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Evoked Potentials, Auditory; Female; Gene Expression Regulation; Indoles; Male; Methylazoxymethanol Acetate; Neurodevelopmental Disorders; Nicotine; Pregnancy; Quinuclidines; Rats; Rats, Sprague-Dawley; Schizophrenia | 2015 |
The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Cognition Disorders; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Male; Mice; Patch-Clamp Techniques; Quinuclidines; Radioligand Assay; Rats; Schizophrenia; Spiro Compounds | 2016 |
TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Behavior, Animal; Benzofurans; Clozapine; Cognition Disorders; Exploratory Behavior; Female; Male; Maze Learning; Mice; Mice, Transgenic; Neurons; Nicotinic Agonists; Promoter Regions, Genetic; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Nicotinic; Reflex, Startle; Schizophrenia; Schizophrenic Psychology; Social Behavior; Tyrosine 3-Monooxygenase | 2009 |
α7 neuronal nicotinic receptor agonist (TC-7020) reverses increased striatal dopamine release during acoustic PPI testing in a transgenic mouse model of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Neural Inhibition; Nicotinic Agonists; Quinuclidines; Receptor, Fibroblast Growth Factor, Type 1; Reflex, Startle; Schizophrenia; Sensory Gating; Thiophenes | 2012 |
[USE OF OXYLIDINE IN THE AMBULATORY TREATMENT OF MENTAL PATIENTS].
Topics: Anxiety; Anxiety Disorders; Cardiovascular Diseases; Delusions; Depression; Guilt; Humans; Hypnotics and Sedatives; Hypochondriasis; Mentally Ill Persons; Meprobamate; Neurotic Disorders; Obsessive-Compulsive Disorder; Paranoid Disorders; Phobic Disorders; Quinuclidines; Schizophrenia; Tranquilizing Agents | 1963 |
Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationsh
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Biological Availability; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cognition Disorders; Drug Stability; Ether-A-Go-Go Potassium Channels; Evoked Potentials, Auditory; Humans; In Vitro Techniques; Learning; Male; Memory; Microsomes, Liver; Neurons; Nicotinic Agonists; Nootropic Agents; Patch-Clamp Techniques; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recognition, Psychology; Schizophrenia; Stereoisomerism; Structure-Activity Relationship | 2006 |
Neurotransmitter receptors in frontal cortex of schizophrenics.
Topics: Adolescent; Adult; Aged; Alprenolol; Antipsychotic Agents; Child; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Neurotransmitter Agents; Norepinephrine; Quinuclidines; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Serotonin; Schizophrenia; Serotonin | 1979 |
[The use of oxylidin in psychiatric practice].
Topics: Adult; Aged; Depression; Female; Ganglionic Blockers; Hallucinations; Humans; Hypochondriasis; Hypotension; Male; Mental Disorders; Middle Aged; Paranoid Disorders; Quinuclidines; Schizophrenia | 1968 |