Compounds > quinuclidines
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quinuclidines and Lung Neoplasms

quinuclidines has been researched along with Lung Neoplasms in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's3 (15.79)29.6817
2010's14 (73.68)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Arunrungvichian, K; Doungchawee, J; Pongrakhananon, V; Pothongsrisit, S; Vajragupta, O; Witayateeraporn, W1
Ailing, Y; Hongyu, X; Liwu, Z; Qingting, W; Xiaoling, S; Xin, L1
El Ashry, ES; Fathy, L; Malki, A1
Iwashima, A; Kagamu, H; Kobayashi, O; Makino, M; Miura, S; Miyao, H; Narita, I; Okajima, M; Sato, K; Tanaka, H; Tanaka, J; Watanabe, S; Yokoyama, A; Yoshizawa, H1
Fukahori, S; Fukuda, Y; Kitazaki, T; Kohno, S; Nakamura, Y; Oyanagi, K; Soda, H1
Enomoto, N; Fujisawa, T; Hayakawa, H; Imokawa, S; Inui, N; Karayama, M; Koshimizu, N; Kuroishi, S; Kusagaya, H; Matsuda, H; Nakamura, Y; Shirai, T; Suda, T; Toyoshima, M; Yamada, T; Yokomura, K1
Fujita, A; Hatsuyama, T; Kobayashi, M; Sato, H; Sekine, K; Umehara, K; Wakamoto, A1
Cao, R; Dong, X; Huang, J; Liu, L1
Christensen, CL; Gerds, TA; Poulsen, HS; Selivanova, G; Willumsen, BM; Zandi, R1
Bergmeier, S; Malki, A1
Buchner, D; Cox, D; Hatoum, HT; Lin, SJ1
Balu, S; Buchner, D; Feinberg, B; Gilmore, J; Haislip, S; Jackson, J; Jain, G1
Hiura, K; Komori, H; Sato, H; Suzuki, C; Yamamoto, M1
Balu, S; Buchner, D; Cox, D; Hatoum, HT; Lin, SJ1
He, X; Hua, N; Liu, X; Ma, X; Wang, L; Wei, X; Yan, H; Zhao, Z; Zheng, J; Zhong, B; Zhuo, R1
Bergman, J; Bykov, VJ; Selivanova, G; Stridh, H; Westman, J; Wiman, KG; Zache, N1
Bergmeier, SC; Evans, SC; Malki, A; Pulipaka, AB1
Advenier, C; Bellamy, JF; Emonds-Alt, X; Molimard, M; Naline, E; Regoli, D1

Trials

5 trial(s) available for quinuclidines and Lung Neoplasms

ArticleYear
Penehyclidine hydrochloride on postoperatively cognitive function.
    Medical hypotheses, 2019, Volume: 129

    Topics: Aged; Anesthesia, General; Atropine; Cholinergic Antagonists; Cognition; Cognitive Dysfunction; Cytokines; Delirium; Female; Humans; Incidence; Inflammation; Lung Neoplasms; Male; Mental Status and Dementia Tests; Postoperative Complications; Postoperative Period; Quinuclidines; Thoracoscopy; Treatment Outcome

2019
The efficacy of triplet antiemetic therapy with 0.75 mg of palonosetron for chemotherapy-induced nausea and vomiting in lung cancer patients receiving highly emetogenic chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:9

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Morpholines; Nausea; Palonosetron; Prospective Studies; Quinuclidines; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Treatment Outcome; Vomiting

2013
Usefulness of antiemetic therapy with aprepitant, palonosetron, and dexamethasone for lung cancer patients on cisplatin-based or carboplatin-based chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:1

    Topics: Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Carboplatin; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Humans; Isoquinolines; Japan; Lung Neoplasms; Male; Middle Aged; Morpholines; Nausea; Palonosetron; Quinuclidines; Salvage Therapy; Surveys and Questionnaires; Treatment Outcome; Vomiting

2015
Evaluation of palonosetron and dexamethasone with or without aprepitant to prevent carboplatin-induced nausea and vomiting in patients with advanced non-small-cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2015, Volume: 90, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Dexamethasone; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Odds Ratio; Palonosetron; Quinuclidines; Treatment Outcome; Vomiting

2015
Palonosetron for prevention of acute and delayed nausea and vomiting in non-small-cell lung carcinoma patients.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:4

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Ondansetron; Palonosetron; Quinuclidines; Vomiting

2011

Other Studies

14 other study(ies) available for quinuclidines and Lung Neoplasms

ArticleYear
α7-Nicotinic acetylcholine receptor antagonist QND7 suppresses non-small cell lung cancer cell proliferation and migration via inhibition of Akt/mTOR signaling.
    Biochemical and biophysical research communications, 2020, 01-22, Volume: 521, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Inhibitory Concentration 50; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Quinuclidines; Signal Transduction; TOR Serine-Threonine Kinases; Triazoles

2020
Novel quinuclidinone derivatives induce apoptosis in lung cancer via sphingomyelinase pathways.
    Drug research, 2013, Volume: 63, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Large Cell; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Quinuclidines; Sphingomyelin Phosphodiesterase

2013
[Comparative Study of the Antiemetic Palonosetron for Lung Cancer Patients Treated with a Divided Dose of Cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:8

    Topics: Antiemetics; Cisplatin; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Nausea; Palonosetron; Quinuclidines; Retrospective Studies; Treatment Outcome; Vomiting

2016
PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-01, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Genes, p53; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Mutant Proteins; Quinuclidines; Small Cell Lung Carcinoma; Time Factors; Xenograft Model Antitumor Assays

2011
Differential apoptotic effects of novel quinuclidinone analogs 8a and 8b in normal and lung cancer cell lines.
    Anticancer research, 2011, Volume: 31, Issue:4

    Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Cycle; Cell Proliferation; Cells, Cultured; Flow Cytometry; Fluorescent Antibody Technique; Gamma Rays; Humans; Lung; Lung Neoplasms; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Quinuclidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingomyelin Phosphodiesterase; Tumor Suppressor Protein p53

2011
Comparative clinical effectiveness of various 5-HT3 RA antiemetic regimens on chemotherapy-induced nausea and vomiting associated with hospital and emergency department visits in real world practice.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:5

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Cisplatin; Cohort Studies; Cyclophosphamide; Databases, Factual; Female; Follow-Up Studies; Hospitalization; Humans; Isoquinolines; Logistic Models; Lung Neoplasms; Male; Middle Aged; Nausea; Palonosetron; Quinuclidines; Retrospective Studies; Serotonin 5-HT3 Receptor Antagonists; Treatment Outcome; Vomiting

2012
Impact of initiating antiemetic prophylaxis with palonosetron versus ondansetron on risk of uncontrolled chemotherapy-induced nausea and vomiting in patients with lung cancer receiving multi-day chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Dexamethasone; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Nausea; Ondansetron; Palonosetron; Quinuclidines; Retrospective Studies; Vomiting

2012
[The efficacy of aprepitant and palonosetron on cisplatin doublet in lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:10

    Topics: Antiemetics; Antineoplastic Agents; Aprepitant; Cisplatin; Female; Humans; Isoquinolines; Lung Neoplasms; Male; Middle Aged; Morpholines; Nausea; Palonosetron; Quinuclidines; Retrospective Studies; Serotonin Antagonists; Vomiting

2011
Impact of 5-HT3 receptor antagonists on chemotherapy-induced nausea and vomiting: a retrospective cohort study.
    BMC health services research, 2012, Jul-23, Volume: 12

    Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Cisplatin; Female; Health Care Surveys; Hospitalization; Humans; Isoquinolines; Logistic Models; Lung Neoplasms; Male; Middle Aged; Nausea; Palonosetron; Quinuclidines; Retrospective Studies; Serotonin 5-HT3 Receptor Antagonists; Vomiting

2012
A novel muscarinic antagonist R2HBJJ inhibits non-small cell lung cancer cell growth and arrests the cell cycle in G0/G1.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents; Benzyl Alcohols; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Female; G1 Phase; Guinea Pigs; Humans; Lung Neoplasms; Models, Biological; Muscarinic Antagonists; Quinuclidines; Resting Phase, Cell Cycle

2012
PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.
    Oncogene, 2005, May-12, Volume: 24, Issue:21

    Topics: Adenocarcinoma; Animals; Apoptosis; Aza Compounds; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Interactions; Drug Resistance, Neoplasm; Genes, p53; Humans; Lung Neoplasms; Mice; Mice, SCID; Mutation; Osteosarcoma; Quinuclidines; Transplantation, Heterologous; Tumor Cells, Cultured

2005
Structure-activity studies of quinuclidinone analogs as anti-proliferative agents in lung cancer cell lines.
    Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Molecular Structure; Quinuclidines; Structure-Activity Relationship; Tumor Suppressor Protein p53

2006
Preventing emesis in lung cancer patients.
    The journal of supportive oncology, 2007, Volume: 5, Issue:2

    Topics: Antiemetics; Antineoplastic Agents; Humans; Isoquinolines; Lung Neoplasms; Ondansetron; Palonosetron; Quinuclidines; Vomiting

2007
Evidence for functional tachykinin NK1 receptors on human isolated small bronchi.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: Benzamides; Biphenyl Compounds; Bronchi; Female; Hormone Antagonists; Humans; In Vitro Techniques; Indomethacin; Lung Neoplasms; Male; Middle Aged; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Substance P

1996