quinpirole has been researched along with Disease Models, Animal in 110 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.73) | 18.7374 |
| 1990's | 14 (12.73) | 18.2507 |
| 2000's | 32 (29.09) | 29.6817 |
| 2010's | 49 (44.55) | 24.3611 |
| 2020's | 12 (10.91) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Cheng, J; Fan, L; Liu, R; Tan, L; Wang, H; Wang, S; Yan, W; Yu, J | 1 |
| Fan, W; Liu, P; Lv, H; Qin, D; Tao, Z; Xu, Y | 1 |
| Fazli-Tabaei, S; Khakpai, F; Zarrindast, MR | 1 |
| Huang, C; Huang, Q; Qu, J; Yang, F; Yang, Y; Zhang, S; Zhou, X | 1 |
| Blezer, ELA; Buitelaar, JK; Dijkhuizen, RM; Glennon, JC; Otte, WM; Smeele, CE; Straathof, M; van der Toorn, A; van Heijningen, C | 1 |
| Akbariqomi, M; Ghafouri-Fard, S; Heidari, R; Jafari, P; Lavasani, PS; Modarressi, MH; Motevaseli, E; Sanikhani, NS; Shafei, S; Vousooghi, N; Yazarlou, F | 1 |
| Hou, X; Huang, F; Qu, J; Shu, Z; Tang, J; Wan, F; Wang, Q; Yan, T; Yang, Y; Zhou, X | 1 |
| Bhide, PG; Brown, RW; Gill, WD; Peeters, LD | 1 |
| Altenhofen, S; Bonan, CD; da Silva, JMK; Gerlai, R; Nabinger, DD; Peixoto, JV | 1 |
| Chen, D; Guo, M; He, F; Jia, Q; Li, M; Li, Y; Sun, S; Sun, Y; Wang, M; Wang, X; Xiang, T; Yao, X; Zhang, X | 1 |
| Bhimani, S; Espinoza, D; Natsheh, JY; Shiflett, MW | 1 |
| Eilam, D | 1 |
| Christensen, KV; Christoffersen, CT; Clausen, D; Didriksen, M; Egebjerg, J; Fejgin, K; Kallunki, P; Larsen, PH; Lauridsen, JB; Mørk, A; Nielsen, J; Nielsen, V; Sotty, F; Werge, TM; Yavich, L | 1 |
| Dvorkin-Gheva, A; Farbod, Y; Jung, PS; Jung, TD; Raveendran, L; Sakic, B; Surette, MG; Szechtman, H | 1 |
| Brown, RW; Burgess, KC; Cummins, ED; DePreter, CC; Gill, WD; Kirby, SL; Owens, AS; Schlitt, MA | 1 |
| Faron-Gorecka, A; Gruca, P; Kusmider, M; Lason-Tyburkiewicz, M; Litwa, E; Niemczyk, M; Papp, M; Solich, J; Szlachta, M; Tota-Glowczyk, K; Willner, P | 1 |
| Boeckers, T; Hengerer, B; Nespoli, E; Rizzo, F; Schulze, U | 1 |
| Ding, JH; Du, RH; Hu, G; Lu, M; Xia, ML; Zhou, Y | 1 |
| Dorfman, A; Eilam, D; Szechtman, H | 1 |
| Brozka, H; Janikova, M; Radostova, D; Stuchlik, A; Svoboda, J | 1 |
| Glorie, D; Servaes, S; Staelens, S; Stroobants, S | 1 |
| Ford, KA; Marinelli, M; McCutcheon, JE; Pagels, NE; Wong, WC | 1 |
| Lee, L; Nickla, DL; Totonelly, K | 1 |
| Barraud, Q; Bezard, E; Ghorayeb, I; Hyacinthe, C; Tison, F | 1 |
| d'Angelo, LS; Day, JO; Dongelmans, ML; Eagle, DM; Mar, AC; Morein-Zamir, S; Noble, CA; Noschang, C; Robbins, TW; Theobald, DE; Urcelay, GP | 1 |
| Cheon, P; Dvorkin-Gheva, A; Kirk, A; Peel, J; Sharma, R; Szechtman, H; Taji, L; Tucci, MC | 1 |
| Cabungcal, JH; Calhoon, GG; Counotte, DS; Cuenod, M; Do, KQ; Hong, LE; Kil, J; Lewis, E; O'Donnell, P; Piantadosi, P; Pollock, C; Presgraves, E; Sullivan, E; Tejeda, HA | 1 |
| Aira, Z; Azkue, JJ; Barrenetxea, T; Buesa, I; Gómez-Esteban, JC | 1 |
| Ballester González, J; Dvorkin-Gheva, A; Foster, JA; Silva, C; Szechtman, H | 1 |
| Dvorkin-Gheva, A; Johnson, E; Szechtman, H; Tucci, MC; Wong, M | 1 |
| Ahluwalia, A; Deng, X; Ostapchenko, L; Paunovic, B; Prysiazhniuk, A; Sandor, Z; Szabo, S; Tarnawski, A; Tolstanova, G | 1 |
| Cerqueira, JJ; Dalla, C; Kokras, N; Leite-Almeida, H; Marques, F; Morgado, P; Pêgo, JM; Ribeiro, B; Rodrigues, AJ; Sousa, N | 1 |
| Brown, RW; Brus, R; Kostrzewa, RM; Nowak, P | 1 |
| Cruz, AV; Delaville, C; Dupre, KB; Eyring, KW; Gerber, CM; McCoy, AJ; Walters, JR | 1 |
| Bye, CR; Ganella, DE; Kim, JH; Lawrence, AJ; Madsen, HB; Perry, CJ; Zbukvic, IC | 1 |
| Ismael, S; Lee, D; Wiemerslage, L | 1 |
| Hatalova, H; Pistikova, A; Radostova, D; Stuchlik, A; Vales, K | 1 |
| Cancela, JM; Fossier, P; Meunier, CNJ | 1 |
| Brown, RW; Burgess, KC; Cummins, ED; Dose, JM; Gill, WD; Hoover, DB; Pauly, JR; Peterson, DJ | 1 |
| Amato, D; Borsini, F; Nencini, P; Stasi, MA | 1 |
| Culver, KE; Dvorkin, A; Kolb, B; Szechtman, H; Waxman, D | 1 |
| Boulougouris, V; Kalogerakou, S; Kontis, D; Papadimitriou, GN; Papadopoulos, S; Papakosta, VM; Poulopoulou, C; Tsaltas, E | 1 |
| Djodari-Irani, A; Harnack, D; Heinz, A; Joel, D; Juckel, G; Klein, J; Kupsch, A; Morgenstern, R; Mundt, A; Orawa, H; Winter, C | 1 |
| Ballion, B; Chetrit, J; Frenois, F; Gonon, F; Murer, MG; Zold, CL | 1 |
| Akil, H; Clark, JJ; Clinton, SM; Flagel, SB; Phillips, PE; Robinson, TE; Seeman, P; Watson, SJ | 1 |
| Lukács, A; Papp, A; Szabó, A; Vezér, T | 1 |
| De Carolis, L; Milella, MS; Nativio, P; Nencini, P; Passarelli, F; Scaccianoce, S; Schepisi, C | 1 |
| Borsini, F; De Carolis, L; Nencini, P; Serlupi-Crescenzi, O; Stasi, MA | 1 |
| Bisnaire, L; Dvorkin, A; Foster, J; McMurran, T; Silva, C; Szechtman, H | 1 |
| Burgess, CR; Gillis, L; Peever, JH; Tse, G | 1 |
| Hamann, M; Lange, N; Richter, A; Shashidharan, P | 1 |
| Albelda, N; Joel, D | 1 |
| De Carolis, L; Milella, MS; Nencini, P; Schepisi, C | 1 |
| Eilam, D; Fineberg, N; Hermesh, H; Zor, R | 1 |
| Böttiger, BW; Knapp, J; Popp, E; Russ, N; Schneider, A; Teschendorf, P; Vogel, P | 1 |
| Bachtell, RK; LeTendre, ML; O'Neill, CE | 1 |
| de Haas, R; Kas, MJ; Oppelaar, H; Seddik, A; Westenberg, HG | 1 |
| Amato, D; Badiani, A; Müller, CP | 1 |
| Gewirtz, JC; Radke, AK | 1 |
| Brown, RW; Cope, ZA; Kostrzewa, RM; Maple, AM; Perna, MK; Sheppard, AB | 1 |
| Baufreton, J; Bezard, E; Bioulac, B; Goillandeau, M; Martinez, A; Miguelez, C; Morin, S | 1 |
| Panagis, G; Rea, E; Schmidt, TT; Shababi-Klein, J; Winter, C | 1 |
| Alkhatib, AH; Dvorkin-Gheva, A; Szechtman, H | 1 |
| Amodeo, S; Cheon, P; Dvorkin-Gheva, A; Graham, D; Kirk, A; Peel, J; Szechtman, H; Taji, L; Tucci, MC | 1 |
| Bizup, B; Grace, AA; Sesia, T | 1 |
| Cai, G; Friedman, E; Torres, C; Zhen, X | 1 |
| Ammassari-Teule, M; Bernardi, G; Berretta, N; Geracitano, R; Guatteo, E; Longone, P; Mercuri, NB; Paolucci, E; Prisco, S; Zona, C | 1 |
| Chancellor, MB; De Groat, WC; Kuno, S; Seki, S; Yoshimura, N | 1 |
| Adachi, K; Fujita, S; Koshikawa, N; Nakamura, S; Okutsu, H; Saigusa, T; Yamaguchi, H | 1 |
| Meredith, GE; Napier, TC; Switzer, RC | 1 |
| Angelatou, F; Ekonomou, A; Matsokis, N; Poulou, PD | 1 |
| Bernardi, G; Calabresi, P; Costa, C; Goldberg, MS; Haburcak, M; Kitada, T; Martella, G; Martins, A; Pisani, A; Pothos, EN; Roth, BL; Shen, J; Tong, Y; Tscherter, A; Vortherms, TA | 1 |
| Eilam, D; Szechtman, H | 1 |
| Bibbiani, F; Chase, TN; Collins, MA; Kielaite, A; Oh, JD; Smith, C | 1 |
| Dvorkin, A; Perreault, ML; Szechtman, H | 1 |
| Anders, S; Gonzales, RA; Job, MO; Low, MJ; Ramachandra, V | 1 |
| Agnati, L; Antonelli, T; Ferraro, L; Fuxe, K; Mazzoni, E; Tanganelli, S; Tomasini, MC | 1 |
| Eilam, D; Ronen, S; Zadicario, P | 1 |
| Harvey, BH; Korff, S; Stein, DJ | 1 |
| Harnack, D; Jalali, R; Joel, D; Juckel, G; Kupsch, A; Morgenstern, R; Mundt, A; Winter, C | 1 |
| Covasa, M; Hajnal, A; Margas, WM | 1 |
| Duvoisin, RC; Gershanik, O; Heikkila, RE | 1 |
| Bentlage, C; Björklund, A; Nikkhah, G; Olsson, M | 1 |
| Drukarch, B; Goosen, C; Sahadat, MC; Stoof, JC; Vermeulen, RJ; Wolters, EC | 1 |
| LeDuc, PA; Mittleman, G; Whishaw, IQ | 1 |
| Gerlach, J; Peacock, L | 1 |
| Misu, Y; Okumura, F; Sato, K; Ueda, H | 1 |
| Fadda, P; Fratta, W; Gessa, GL; Pani, L | 1 |
| Mignot, E; Nishino, S; Reid, MS; Sampathkumaran, R; Siegel, JM; Tafti, M | 1 |
| Brotchie, JM; Fox, SH; Moser, B | 1 |
| Sachdev, PS; Saharov, T | 1 |
| Eilam, D; Sulis, W; Szechtman, H | 1 |
| Ahmad, B; Darmani, NA; Zhao, W | 1 |
| Adachi, K; Cools, AR; Hasegawa, M; Hirose, N; Ikeda, H; Koshikawa, N; Sato, M | 1 |
| Jackson, MJ; Jenner, P; Kanda, T; Kase, H; Kuwana, Y; Nakamura, J; Pearce, RK; Smith, LA | 1 |
| de Villiers, AS; Lamm, MC; Russell, VA; Sagvolden, T; Taljaard, JJ | 1 |
| Ferré, S; Fuxe, K; Müller, CE; Popoli, P; Strömberg, I | 1 |
| Caron, MG; Gainetdinov, RR; Hen, R; Jones, SR; Miller, GW; Oosting, RS; Zhuang, X | 1 |
| Boersma, JT; Bonura, CA; Culver, KE; Eckert, MJ; Eilam, D; McClelland, JZ; Szechtman, H; Tse, WS | 1 |
| Okuyama, S; Takamori, K; Yoshida, S | 1 |
| Avisar, A; Doljansky, J; Joel, D | 1 |
| Glavan, G; Sket, D; Zivin, M | 1 |
| Culver, KE; Louis, VA; Szechtman, H; Taylor, CT; Tizabi, Y; Waxman, D | 1 |
| Belmaker, RH; Einat, H; Shaldubina, A; Shimon, H; Szechtman, H | 1 |
| Muscat, R; Papp, M; Willner, P | 1 |
| Braff, DL; Geyer, MA; Mansbach, RS; Peng, RY | 1 |
| Egawa, M; Friedhoff, AJ; Rosengarten, H; Schweitzer, JW | 1 |
| Jenner, P; Marsden, CD | 1 |
6 review(s) available for quinpirole and Disease Models, Animal
| Article | Year |
|---|---|
From an animal model to human patients: An example of a translational study on obsessive compulsive disorder (OCD).
Topics: Animals; Disease Models, Animal; Humans; Obsessive-Compulsive Disorder; Quinpirole; Translational Research, Biomedical | 2017 |
Animal models of obsessive-compulsive disorder: exploring pharmacology and neural substrates.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Deep Brain Stimulation; Disease Models, Animal; Dopamine Agonists; Exploratory Behavior; Hormones; Humans; Mice; Obsessive-Compulsive Disorder; Quinpirole; Reproducibility of Results | 2012 |
Animal behavior as a conceptual framework for the study of obsessive-compulsive disorder (OCD).
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Humans; Mental Disorders; Obsessive-Compulsive Disorder; Quinpirole; Rats; Telemetry; Terminology as Topic; Video Recording | 2012 |
Schizophrenia and substance abuse comorbidity: nicotine addiction and the neonatal quinpirole model.
Topics: Animals; Behavior, Addictive; Disease Models, Animal; Nicotine; Quinpirole; Schizophrenia; Tobacco Use Disorder | 2012 |
Psychostimulant-induced behavior as an animal model of obsessive-compulsive disorder: an ethological approach to the form of compulsive rituals.
Topics: Animals; Brain; Central Nervous System Stimulants; Ceremonial Behavior; Disease Models, Animal; Dopamine; Dopamine Agonists; Ethology; Humans; Obsessive-Compulsive Disorder; Quinpirole; Rats; Stereotyped Behavior | 2005 |
The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Callithrix; Corpus Striatum; Disease Models, Animal; Dopamine; Ergolines; Humans; Levodopa; Macaca mulatta; Neural Pathways; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Quinpirole; Rats; Saimiri; Selegiline; Species Specificity; Substantia Nigra | 1986 |
104 other study(ies) available for quinpirole and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
2-Phenylcyclopropylmethylamine Derivatives as Dopamine D
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Dopamine Agonists; Drug Design; Drug Evaluation, Preclinical; Half-Life; Humans; Mice; Mice, Inbred ICR; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship | 2021 |
Neuroprotective effects of dopamine D2 receptor agonist on neuroinflammatory injury in olfactory bulb neurons in vitro and in vivo in a mouse model of allergic rhinitis.
Topics: Animals; Blotting, Western; Coculture Techniques; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroinflammatory Diseases; Neurons; Neuroprotective Agents; Olfactory Bulb; Quinpirole; Receptors, AMPA; Receptors, Dopamine D2; Rhinitis, Allergic; Smell | 2021 |
Synergistic effect between quinpirole and L-NAME as well as sulpiride and L-arginine on the modulation of anxiety and memory processes in the 6-OHDA mouse model of Parkinson's disease: An isobologram analysis.
Topics: Adrenergic Agents; Animals; Anxiety; Arginine; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Therapy, Combination; Enzyme Inhibitors; Male; Memory; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Parkinson Disease; Quinpirole; Receptors, Dopamine D2; Sulpiride | 2021 |
Decreased Choroidal Blood Perfusion Induces Myopia in Guinea Pigs.
Topics: Actins; Animals; Axial Length, Eye; Blood Flow Velocity; Blotting, Western; Choroid; Ciliary Arteries; Computed Tomography Angiography; Disease Models, Animal; Dopamine Agonists; Electroretinography; Guinea Pigs; Hypoxia; Muscle, Smooth; Myopia; Phenylephrine; Quinpirole; Receptors, Dopamine D2; Refraction, Ocular; Regional Blood Flow; Sclera; Tomography, Optical Coherence | 2021 |
Memantine treatment does not affect compulsive behavior or frontostriatal connectivity in an adolescent rat model for quinpirole-induced compulsive checking behavior.
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Dopamine Agonists; Memantine; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Rats, Sprague-Dawley | 2022 |
The Effect of Lactobacillus casei Consumption in Improvement of Obsessive-Compulsive Disorder: an Animal Study.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopamine Agonists; Fluoxetine; Gene Expression Regulation; Lacticaseibacillus casei; Male; Obsessive-Compulsive Disorder; Prefrontal Cortex; Probiotics; Quinpirole; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin Plasma Membrane Transport Proteins | 2020 |
The Role of the Dopamine D2 Receptor in Form-Deprivation Myopia in Mice: Studies With Full and Partial D2 Receptor Agonists and Knockouts.
Topics: Animals; Disease Models, Animal; Dopamine Agonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myopia; Quinpirole; Receptors, Dopamine D2; Signal Transduction | 2020 |
The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Animals, Newborn; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Male; Motor Activity; Nucleus Accumbens; Phenethylamines; Prepulse Inhibition; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Schizophrenia; Sensory Gating | 2020 |
Feeding status alters exploratory and anxiety-like behaviors in zebrafish larvae exposed to quinpirole.
Topics: Animals; Anxiety; Disease Models, Animal; Dopamine Agonists; Eating; Exploratory Behavior; Female; Larva; Male; Quinpirole; Zebrafish | 2021 |
Effects of intrastriatal injection of the dopamine receptor agonist SKF38393 and quinpirole on locomotor behavior in hemiparkinsonism rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Locomotion; Male; Motor Activity; Parkinson Disease; Parkinsonian Disorders; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2021 |
The effects of the dopamine D2/3 agonist quinpirole on incentive value and palatability-based choice in a rodent model of attention-deficit/hyperactivity disorder.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Dopamine; Dopamine Agonists; Motivation; Quinpirole; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rodentia | 2021 |
A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
Topics: Abnormalities, Multiple; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Chromosome Deletion; Chromosomes, Human, Pair 1; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; Megalencephaly; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Phencyclidine; Phenotype; Prepulse Inhibition; Quinpirole; Receptors, Dopamine; Schizophrenia; Ventral Tegmental Area | 2017 |
Changes in gut microbiota during development of compulsive checking and locomotor sensitization induced by chronic treatment with the dopamine agonist quinpirole.
Topics: Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dopamine Agonists; Gastrointestinal Microbiome; Locomotion; Male; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine; RNA, Ribosomal, 16S; Stereotyped Behavior | 2018 |
Effects of Environmental Enrichment on Nicotine Sensitization in Rats Neonatally Treated with Quinpirole: Analyses of Glial Cell Line-Derived Neurotrophic Factor and Implications towards Schizophrenia.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Dopamine Agonists; Female; Glial Cell Line-Derived Neurotrophic Factor; Housing, Animal; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Quinpirole; Rats; Schizophrenia; Substance-Related Disorders | 2018 |
Effects on brain-derived neurotrophic factor signalling of chronic mild stress, chronic risperidone and acute intracranial dopamine receptor challenges.
Topics: Animals; Antipsychotic Agents; Benzazepines; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopamine Agents; Electroencephalography; Male; Prefrontal Cortex; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Risperidone; RNA, Messenger; Signal Transduction; Stress, Psychological | 2018 |
Altered dopaminergic regulation of the dorsal striatum is able to induce tic-like movements in juvenile rats.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Down-Regulation; Haloperidol; Male; Motor Activity; Oxidopamine; Phenotype; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Tourette Syndrome | 2018 |
α-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering β-arrestin2-TAB1 interaction in astrocytes.
Topics: Adaptor Proteins, Signal Transducing; alpha-Synuclein; Animals; Animals, Newborn; Astrocytes; beta-Arrestin 2; Cells, Cultured; Disease Models, Animal; Dopamine Agonists; Embryo, Mammalian; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; MPTP Poisoning; Mutation; Neurons; Protein Binding; Quinpirole; Receptors, Dopamine D2; Signal Transduction; Tyrosine 3-Monooxygenase | 2018 |
Social interaction modulates the intensity of compulsive checking in a rat model of obsessive-compulsive disorder (OCD).
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Male; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats, Sprague-Dawley; Severity of Illness Index; Social Behavior | 2019 |
No effect of riluzole and memantine on learning deficit following quinpirole sensitization - An animal model of obsessive-compulsive disorder.
Topics: Animals; Behavior, Animal; Cognition; Disease Models, Animal; Dopamine Agonists; Excitatory Amino Acid Antagonists; Learning; Male; Memantine; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Riluzole | 2019 |
Neuroreceptor kinetics in rats repeatedly exposed to quinpirole as a model for OCD.
Topics: Animals; Disease Models, Animal; Dopamine Agonists; Gene Expression Regulation; Glutamate Plasma Membrane Transport Proteins; Kinetics; Male; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D2 | 2019 |
Adolescents are more vulnerable to cocaine addiction: behavioral and electrophysiological evidence.
Topics: Action Potentials; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Quinpirole; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Self Administration; Time Factors; Ventral Tegmental Area | 2013 |
Nitric oxide synthase inhibitors prevent the growth-inhibiting effects of quinpirole.
Topics: Animals; Animals, Newborn; Arginine; Chickens; Disease Models, Animal; Dopamine Agonists; Drug Combinations; Eye; Injections, Intraocular; Myopia; Nitric Oxide Synthase; Ornithine; Quinpirole; Refraction, Ocular; Sensory Deprivation; Ultrasonography | 2013 |
D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Electrocardiography; Electroencephalography; Electromyography; Female; Levodopa; Macaca fascicularis; Macaca mulatta; Parkinsonian Disorders; Quinpirole; Sleep; Sleep Disorders, Circadian Rhythm; Telemetry; Time Factors; Wakefulness | 2014 |
The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD.
Topics: Animals; Anxiety; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Male; Maze Learning; Observation; Psychomotor Performance; Quinpirole; Rats; Reinforcement Schedule; Reinforcement, Psychology; Statistics, Nonparametric; Sulpiride | 2014 |
Separate mechanisms for development and performance of compulsive checking in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD).
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Male; Obsessive-Compulsive Disorder; Piperazines; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Serotonin Receptor Agonists | 2014 |
Juvenile antioxidant treatment prevents adult deficits in a developmental model of schizophrenia.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; Hippocampus; Ibotenic Acid; In Vitro Techniques; Neurons; Pregnancy; Quinpirole; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia | 2014 |
Synaptic upregulation and superadditive interaction of dopamine D2- and μ-opioid receptors after peripheral nerve injury.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Dopamine Agonists; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Evoked Potentials; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Nerve Fibers, Unmyelinated; Peripheral Nerve Injuries; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; Somatostatin; Synapses; Synaptophysin; Up-Regulation | 2014 |
Nucleus accumbens core and pathogenesis of compulsive checking.
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Hyperkinesis; Male; Nucleus Accumbens; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Dopamine D3 | 2015 |
5-HT2A/C receptors do not mediate the attenuation of compulsive checking by mCPP in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD).
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Male; Obsessive-Compulsive Disorder; Piperazines; Quinpirole; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Ritanserin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists | 2015 |
Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease.
Topics: Animals; Biopsy, Needle; Blotting, Western; Cabergoline; Capillary Permeability; Colitis, Ulcerative; Disease Models, Animal; Dopamine; Ergolines; Female; Humans; Immunohistochemistry; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-10; Iodoacetamide; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinpirole; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Statistics, Nonparametric | 2015 |
Stress induced risk-aversion is reverted by D2/D3 agonist in the rat.
Topics: Animals; Chronic Disease; Decision Making; Disease Models, Animal; Dopamine; Dopamine Agonists; Male; Prefrontal Cortex; Pyramidal Cells; Quinpirole; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Risk-Taking; RNA, Messenger; Stress, Psychological; Uncertainty | 2015 |
Perinatal Treatments with the Dopamine D₂-Receptor Agonist Quinpirole Produces Permanent D₂-Receptor Supersensitization: a Model of Schizophrenia.
Topics: Amphetamines; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Exocytosis; Female; GTP-Binding Proteins; Humans; Locomotion; Male; Quinpirole; Rats; Receptors, Dopamine D2; Schizophrenia; Sex Factors | 2016 |
Effects of L-dopa priming on cortical high beta and high gamma oscillatory activity in a rodent model of Parkinson's disease.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Gamma Rhythm; Levodopa; Male; Motor Activity; Motor Cortex; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 2016 |
Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Extinction, Psychological; Learning; Male; Motivation; Prefrontal Cortex; Quinpirole; Random Allocation; Rats, Sprague-Dawley; Receptors, Dopamine D2; Self Administration | 2016 |
Early alterations of mitochondrial morphology in dopaminergic neurons from Parkinson's disease-like pathology and time-dependent neuroprotection with D2 receptor activation.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Mitochondria; Neuroprotection; Parkinson Disease; Quinpirole; Receptors, Dopamine D2 | 2016 |
Detrimental effect of clomipramine on hippocampus-dependent learning in an animal model of obsessive-compulsive disorder induced by sensitization with d2/d3 agonist quinpirole.
Topics: Analysis of Variance; Animals; Avoidance Learning; Clomipramine; Disease Models, Animal; Dopamine Agonists; Electroshock; Escape Reaction; Hippocampus; Locomotion; Male; Maze Learning; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 2017 |
Lack of GSK3β activation and modulation of synaptic plasticity by dopamine in 5-HT1A-receptor KO mice.
Topics: Animals; Anxiety; Disease Models, Animal; Dopamine Agonists; Excitatory Postsynaptic Potentials; Glycogen Synthase Kinase 3 beta; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Mice, Knockout; Neuronal Plasticity; Prefrontal Cortex; Pyramidal Cells; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 2017 |
The effects of nicotine in the neonatal quinpirole rodent model of psychosis: Neural plasticity mechanisms and nicotinic receptor changes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Disease Models, Animal; Female; Male; Motor Activity; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Psychotic Disorders; Quinpirole; Rats, Sprague-Dawley; Receptors, Nicotinic | 2017 |
Haloperidol both prevents and reverses quinpirole-induced nonregulatory water intake, a putative animal model of psychogenic polydipsia.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Benzodiazepines; Clomipramine; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Haloperidol; Male; Olanzapine; Piperazines; Pyrroles; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Thiazepines | 2008 |
Effects of hypophysectomy on compulsive checking and cortical dendrites in an animal model of obsessive-compulsive disorder.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Compulsive Behavior; Dendrites; Disease Models, Animal; Hypophysectomy; Injections, Subcutaneous; Male; Motor Activity; Neuronal Plasticity; Obsessive-Compulsive Disorder; Pituitary Hormones; Quinpirole; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Dopamine D3 | 2008 |
Dopaminergic and serotonergic modulation of persistent behaviour in the reinforced spatial alternation model of obsessive-compulsive disorder.
Topics: Animals; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Fluoxetine; Male; Maze Learning; Obsessive-Compulsive Disorder; Piperazines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Time Factors | 2008 |
High-frequency stimulation of the nucleus accumbens core and shell reduces quinpirole-induced compulsive checking in rats.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Electric Stimulation Therapy; Male; Neural Pathways; Nucleus Accumbens; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Wistar; Synaptic Transmission | 2009 |
D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2009 |
An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction.
Topics: Animals; Behavior, Addictive; Conditioning, Classical; Cues; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Genetics, Behavioral; Impulsive Behavior; Male; Phenotype; Psychomotor Performance; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reward; RNA, Messenger | 2010 |
Altered open field behavior in rats induced by acute administration of 3-nitropropionic acid: possible glutamatergic and dopaminergic involvement.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Agents; Huntington Disease; Male; Motor Activity; N-Methylaspartate; Nitro Compounds; Propionates; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Glutamate; Sulpiride | 2009 |
Opposite roles of dopamine and orexin in quinpirole-induced excessive drinking: a rat model of psychotic polydipsia.
Topics: Animals; Benzoxazoles; Cerebral Cortex; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drinking; Drug Synergism; Haloperidol; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexins; Psychotic Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Urea | 2010 |
The effects of clozapine on quinpirole-induced non-regulatory drinking and prepulse inhibition disruption in rats.
Topics: Animals; Antipsychotic Agents; Brain; Brain-Derived Neurotrophic Factor; Clozapine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drinking; Gene Expression Regulation; Haloperidol; Male; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Schizophrenia | 2010 |
Features of compulsive checking behavior mediated by nucleus accumbens and orbital frontal cortex.
Topics: Amygdala; Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Frontal Lobe; Motor Activity; Neuropsychological Tests; Nucleus Accumbens; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans | 2010 |
Dopaminergic regulation of sleep and cataplexy in a murine model of narcolepsy.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Cataplexy; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Electromyography; Male; Mice; Mice, Knockout; Narcolepsy; Quinpirole; Receptors, Dopamine; Salicylamides; Sleep; Videotape Recording | 2010 |
Behavioural and pharmacological examinations in a transgenic mouse model of early-onset torsion dystonia.
Topics: Amphetamines; Animals; Anxiety; Behavior, Animal; Carbidopa; Chromans; Disease Models, Animal; Dystonia; Levodopa; Locomotion; Mice; Mice, Transgenic; Quinpirole; Raclopride | 2011 |
Clomipramine, but not haloperidol or aripiprazole, inhibits quinpirole-induced water contrafreeloading, a putative animal model of compulsive behavior.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aripiprazole; Clomipramine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drinking Behavior; Haloperidol; Male; Piperazines; Quinolones; Quinpirole; Rats; Rats, Sprague-Dawley | 2011 |
Facilitation of hypothermia by quinpirole and 8-OH-DPAT in a rat model of cardiac arrest.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Cardiopulmonary Resuscitation; Disease Models, Animal; Dopamine Agonists; Heart Arrest; Hypothermia, Induced; Male; Quinpirole; Rats; Rats, Wistar; Recovery of Function; Serotonin Receptor Agonists; Treatment Outcome; Ventricular Fibrillation | 2012 |
Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Locomotion; Male; Nucleus Accumbens; Phenethylamines; Purinergic P2X Receptor Antagonists; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reinforcement, Psychology; Self Administration; Sucrose; Sweetening Agents; Xanthines | 2012 |
Marked inbred mouse strain difference in the expression of quinpirole induced compulsive like behavior based on behavioral pattern analysis.
Topics: Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Species Specificity | 2012 |
Increased drinking after intra-striatal injection of the dopamine D2/D3 receptor agonist quinpirole in the rat.
Topics: Animals; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Drinking; Male; Microinjections; Polydipsia, Psychogenic; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Time Factors | 2012 |
Increased dopamine receptor activity in the nucleus accumbens shell ameliorates anxiety during drug withdrawal.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Apomorphine; Benzazepines; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Morphine; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reflex, Startle; Substance Withdrawal Syndrome | 2012 |
Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson's disease.
Topics: Animals; Calcium; Disease Models, Animal; Dopamine; Dopamine Agonists; GABAergic Neurons; Globus Pallidus; Inhibitory Postsynaptic Potentials; Miniature Postsynaptic Potentials; Optogenetics; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Strontium | 2012 |
Enhanced reward-facilitating effects of d-amphetamine in rats in the quinpirole model of obsessive-compulsive disorder.
Topics: Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Disease Models, Animal; Dopamine Antagonists; Electric Stimulation; Haloperidol; Male; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Wistar; Reward; Self Administration | 2013 |
Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Compulsive Behavior; Disease Models, Animal; Dopaminergic Neurons; Drug Interactions; Male; Nerve Tissue Proteins; Neurons; Obsessive-Compulsive Disorder; Quinpirole; Random Allocation; Rats; Rats, Long-Evans; Serotonergic Neurons; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Receptor Agonists; Spatial Behavior | 2013 |
Effects of the serotonergic agonist mCPP on male rats in the quinpirole sensitization model of obsessive-compulsive disorder (OCD).
Topics: Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Obsessive-Compulsive Disorder; Piperazines; Quinpirole; Rats; Rats, Long-Evans; Serotonin Receptor Agonists; Time Factors | 2013 |
Evaluation of animal models of obsessive-compulsive disorder: correlation with phasic dopamine neuron activity.
Topics: Action Potentials; Animals; Animals, Newborn; Clomipramine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Extinction, Psychological; Male; Maze Learning; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Ventral Tegmental Area | 2013 |
Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Oxidopamine; Parkinson Disease; PC12 Cells; Phosphorylation; Protein Tyrosine Phosphatases; Quinpirole; Rats; Receptors, Dopamine D2; Sympatholytics; Tyrosine; Vanadates | 2002 |
Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY(93)-->ALA) mutation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Alanine; Animals; Avoidance Learning; Calcium; Cell Membrane; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Electric Stimulation; Genotype; Glycine; Gyrus Cinguli; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity; Mutation; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinpirole; Superoxide Dismutase; Valine | 2003 |
Dopaminergic mechanisms underlying bladder hyperactivity in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzopyrans; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Intraventricular; Male; Microinjections; Oxazines; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Substantia Nigra; Urinary Bladder; Urination | 2003 |
Altered pre- and postsynaptic dopamine receptor functions in spontaneously hypertensive rat: an animal model of attention-deficit hyperactivity disorder.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Locomotion; Male; Mandible; Motor Activity; Movement; Nucleus Accumbens; Quinpirole; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine; Receptors, Presynaptic; Synapses | 2003 |
Short-term, D2 receptor blockade induces synaptic degeneration, reduces levels of tyrosine hydroxylase and brain-derived neurotrophic factor, and enhances D2-mediated firing in the ventral pallidum.
Topics: Animals; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cell Survival; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Administration Schedule; Dyskinesia, Drug-Induced; Haloperidol; Immunohistochemistry; Male; Microscopy, Electron; Nerve Degeneration; Presynaptic Terminals; Prosencephalon; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Salicylamides; Synaptic Transmission; Tyrosine 3-Monooxygenase | 2004 |
Stimulation of adenosine A2A receptors elicits zif/268 and NMDA epsilon2 subunit mRNA expression in cortex and striatum of the "weaver" mutant mouse, a genetic model of nigrostriatal dopamine deficiency.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Autoradiography; Binding Sites; Cell Count; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Dopamine; Dopamine Agonists; Dopamine Antagonists; Early Growth Response Protein 1; Gene Expression; Immediate-Early Proteins; In Situ Hybridization; Mice; Mice, Neurologic Mutants; Phenethylamines; Protein Subunits; Quinpirole; Raclopride; Receptor, Adenosine A2B; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Staining and Labeling; Transcription Factors | 2004 |
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Age Factors; Animals; Behavior, Animal; Blotting, Southern; Blotting, Western; Cell Count; Cerebral Cortex; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; Electrochemistry; Excitatory Postsynaptic Potentials; Germ-Line Mutation; Humans; Hypokinesia; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Oncogene Proteins; Parkinsonian Disorders; Protein Deglycase DJ-1; Quinpirole; Radioligand Assay; Receptors, Dopamine D2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD.
Topics: Amantadine; Animals; Antiparkinson Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Haplorhini; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Time Factors | 2005 |
Development and temporal organization of compulsive checking induced by repeated injections of the dopamine agonist quinpirole in an animal model of obsessive-compulsive disorder.
Topics: Analysis of Variance; Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Male; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Spatial Behavior; Stereotyped Behavior | 2006 |
Reduced basal and ethanol stimulation of striatal extracellular dopamine concentrations in dopamine D2 receptor knockout mice.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Basal Ganglia; Calcium; Calcium Signaling; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Down-Regulation; Ethanol; Extracellular Fluid; Mice; Mice, Knockout; Neural Pathways; Nucleus Accumbens; Quinpirole; Receptors, Dopamine D2; Ventral Tegmental Area | 2006 |
Experimental studies and theoretical aspects on A2A/D2 receptor interactions in a model of Parkinson's disease. Relevance for L-dopa induced dyskinesias.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adrenergic Agents; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Models, Biological; Oxidopamine; Parkinson Disease; Phenethylamines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2 | 2006 |
Modulation of quinpirole-induced compulsive-like behavior in rats by environmental changes: implications for OCD rituals and for exploration and navigation.
Topics: Adaptation, Physiological; Adaptation, Psychological; Animals; Cues; Disease Models, Animal; Dopamine Agonists; Environment; Exploratory Behavior; Obsessive Behavior; Obsessive-Compulsive Disorder; Orientation; Quinpirole; Rats | 2007 |
Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Desipramine; Disease Models, Animal; Dopamine Agonists; Drug Evaluation, Preclinical; Female; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Peromyscus; Piperazines; Quinpirole; Receptors, Dopamine D2; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Species Specificity; Stereotyped Behavior | 2008 |
High frequency stimulation and temporary inactivation of the subthalamic nucleus reduce quinpirole-induced compulsive checking behavior in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Administration Routes; Electric Stimulation; Exploratory Behavior; GABA Agonists; Locomotion; Male; Muscimol; Quinpirole; Rats; Rats, Wistar; Subthalamic Nucleus | 2008 |
Altered dopamine D2 receptor function and binding in obese OLETF rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Glucose Tolerance Test; Iodine Radioisotopes; Male; Motor Activity; Obesity; Protein Binding; Quinpirole; Rats; Rats, Inbred OLETF; Receptors, Dopamine D2; Sucrose; Sulpiride | 2008 |
Behavioral correlations of dopamine receptor activation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, Animal; Ergolines; Female; Locomotion; Mice; Mice, Inbred Strains; Parkinson Disease; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine | 1983 |
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Carbidopa; Dextroamphetamine; Disease Models, Animal; Dopamine; Dopamine Agonists; Ergolines; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Levodopa; Motor Activity; Movement Disorders; Norepinephrine; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Transplantation, Heterotopic | 1995 |
The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys.
Topics: Analysis of Variance; Animals; Benzazepines; Disease Models, Animal; Dopamine Agents; Ergolines; Macaca mulatta; Male; Motor Activity; MPTP Poisoning; Parkinson Disease; Quinpirole; Remoxipride | 1993 |
The role of D1 and D2 receptors in the heightened locomotion induced by direct and indirect dopamine agonists in rats with hippocampal damage: an animal analogue of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Arousal; Brain Mapping; Dextroamphetamine; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Ergolines; Hippocampus; Male; Motor Activity; Quinpirole; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Stereotyped Behavior | 1993 |
Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol.
Topics: Administration, Oral; Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Benzothiazoles; Cebus; Disease Models, Animal; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dyskinesia, Drug-Induced; Dystonia; Ergolines; Female; Haloperidol; Lisuride; Male; Piperidines; Pramipexole; Quinpirole; Raclopride; Salicylamides; Thiazoles | 1993 |
L-DOPA inhibits spontaneous acetylcholine release from the striatum of experimental Parkinson's model rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Drug Synergism; Ergolines; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes | 1995 |
Sleep deprivation in the rat: an animal model of mania.
Topics: Animals; Bipolar Disorder; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Ergolines; Lithium; Narcotics; Quinpirole; Rats; Sleep Deprivation | 1995 |
Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine.
Topics: Amygdala; Animals; Azepines; Cataplexy; Disease Models, Animal; Dogs; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Electromyography; Electrooculography; Female; Globus Pallidus; Male; Microdialysis; Pons; Putamen; Quinpirole; Raclopride; Reticular Formation; Salicylamides; Sleep, REM; Tetrahydronaphthalenes; Ventral Tegmental Area | 1996 |
Behavioral effects of 5-HT2C receptor antagonism in the substantia nigra zona reticulata of the 6-hydroxydopamine-lesioned rat model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Excitatory Amino Acid Antagonists; Indoles; Kynurenic Acid; Locomotion; Male; Microinjections; Oxidopamine; Parkinson Disease, Secondary; Pyridines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Substantia Nigra; Sympatholytics; Urea | 1998 |
Effects of specific dopamine D1 and D2 receptor antagonists and agonists and neuroleptic drugs on emotional defecation in a rat model of akathisia.
Topics: Akathisia, Drug-Induced; Animals; Antipsychotic Agents; Arousal; Benzazepines; Brain; Defecation; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Emotions; Humans; Male; Quinpirole; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 1998 |
Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD).
Topics: Animals; Clomipramine; Disease Models, Animal; Dopamine Agonists; Male; Obsessive-Compulsive Disorder; Orientation; Quinpirole; Rats; Rats, Long-Evans; Selective Serotonin Reuptake Inhibitors; Stereotyped Behavior | 1998 |
The role of D2 and D3 dopamine receptors in the mediation of emesis in Cryptotis parva (the least shrew).
Topics: Analysis of Variance; Animals; Apomorphine; Benzopyrans; Brain Chemistry; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Indans; Male; Oxazines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Shrews; Species Specificity; Sulpiride; Tetrahydronaphthalenes; Vomiting | 1999 |
Effects of chronic haloperidol and clozapine on vacuous chewing and dopamine-mediated jaw movements in rats: evaluation of a revised animal model of tardive dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Clozapine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dyskinesia, Drug-Induced; Haloperidol; Jaw; Male; Mastication; Quinpirole; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Serotonin Antagonists | 1999 |
Combined use of the adenosine A(2A) antagonist KW-6002 with L-DOPA or with selective D1 or D2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Animals; Callithrix; Carbidopa; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Injections, Intraperitoneal; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Purinergic P1 Receptor Antagonists; Purines; Quinpirole; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2000 |
Methylphenidate affects striatal dopamine differently in an animal model for attention-deficit/hyperactivity disorder--the spontaneously hypertensive rat.
Topics: Acetylcholine; Animals; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Electric Stimulation; Male; Methylphenidate; Neostriatum; Neurons; Quinpirole; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine D2; Sulpiride; Synapses | 2000 |
Electrophysiological and behavioural evidence for an antagonistic modulatory role of adenosine A2A receptors in dopamine D2 receptor regulation in the rat dopamine-denervated striatum.
Topics: Adenosine; Animals; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; Functional Laterality; Humans; Male; Oxidopamine; Parkinson Disease; Phenethylamines; Purinergic P1 Receptor Antagonists; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, Purinergic P1; Reference Values | 2000 |
Hyperactivity and impaired response habituation in hyperdopaminergic mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Apomorphine; Attention Deficit Disorder with Hyperactivity; Benzazepines; Carrier Proteins; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Female; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Nerve Tissue Proteins; Psychomotor Agitation; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2001 |
Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Exploratory Behavior; Male; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Spatial Behavior; Time Factors | 2001 |
Repeated treatment with imipramine, fluvoxamine and tranylcypromine decreases the number of escape failures by activating dopaminergic systems in a rat learned helplessness test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Escape Reaction; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Tranylcypromine | 2001 |
Enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the D1 antagonist SCH 23390 or the D2 agonist quinpirole, but not the D1 agonist SKF 38393 or the D2 antagonist haloperidol.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Feedback, Physiological; Male; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Signal Transduction; Stereotyped Behavior | 2001 |
Modulation of neuroleptic activity of 9,10-didehydro-N-methyl-(2-propynyl)-6-methyl-8-aminomethylergoline bimaleinate (LEK-8829) by D1 intrinsic activity in hemi-parkinsonian rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Corpus Striatum; Disease Models, Animal; Drug Interactions; Female; Gene Expression; Lysergic Acid; Neurotensin; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; RNA, Messenger; Tyrosine 3-Monooxygenase | 2002 |
Effect of nicotine on quinpirole-induced checking behavior in rats: implications for obsessive-compulsive disorder.
Topics: Animals; Brain; Disease Models, Animal; Humans; Injections, Subcutaneous; Male; Motor Activity; Nicotine; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Receptors, Nicotinic; Stereotyped Behavior | 2002 |
Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder.
Topics: Administration, Oral; Animals; Anticonvulsants; Bipolar Disorder; Brain; Carbamazepine; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Fructose; Hyperkinesis; Motor Activity; Neurons; Phenytoin; Quinpirole; Rats; Receptors, Dopamine; Topiramate; Valproic Acid | 2002 |
Antidepressant-like effects of dopamine agonists in an animal model of depression.
Topics: Animals; Arousal; Brain; Bromocriptine; Depressive Disorder; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Drinking; Ergolines; Helplessness, Learned; Male; Motivation; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Taste | 1992 |
A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acoustic Stimulation; Animals; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Ergolines; Humans; Male; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Reflex, Startle; Schizophrenia; Schizophrenic Psychology | 1990 |
Diminished D2 dopamine receptor function and the emergence of repetitive jaw movements.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, Animal; Dopamine Antagonists; Dyskinesia, Drug-Induced; Ergolines; Fluphenazine; Male; Quinolines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior | 1988 |