Compounds > quinoxalines
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quinoxalines and Precancerous Conditions

quinoxalines has been researched along with Precancerous Conditions in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's5 (31.25)18.2507
2000's8 (50.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lubet, RA; Miller, MS; Pan, J; Szabo, E; Wang, Y; Xiong, D; You, M; Zhang, Q1
Fukushima, S; Furukawa, F; Hirose, M; Imaida, K; Konishi, Y; Morimura, K; Nakae, D; Shirai, T; Tatematsu, M; Totsuka, Y; Tsuda, H; Tsukamoto, T; Uehara, N; Wakabayashi, K; Wanibuchi, H; Wei, M1
Fukushima, S; Furukawa, F; Hirose, M; Imaida, K; Konishi, Y; Morimura, K; Nakae, D; Shirai, T; Takasuka, N; Tatematsu, M; Tsuda, H; Tsukamoto, T; Wanibuchi, H; Wei, M1
Fukushima, S; Nakae, D; Nishkawa, T; Ogawa, M; Otani, S; Totsuka, Y; Wakabayashi, K; Wanibuchi, H; Yano, Y1
Fukushima, S; Ichihara, T; Morimura, K; Nakae, D; Totsuka, Y; Wanibuchi, H; Wei, M1
Fukushima, S; Hori, TA; Ichihara, T; Kang, JS; Morimura, K; Puatanachokchai, R; Wanibuchi, H; Wei, M1
Fukushima, S; Kang, JS; Mori, S; Morimura, K; Murai, T; Totsuka, Y; Wanibuchi, H1
Cui, L; Hasegawa, R; Hirose, M; Ito, N; Kato, T; Kobayashi, Y; Konishi, Y; Nakae, D; Shirai, T; Yaono, M1
Sugimura, T1
Fukushima, S1
Bergman, J; Möller, L; Rozell, BL; Skarin, T; Toftgård, R1
Hirose, M; Kawabe, M; Kimoto, N; Lin, C; Sano, M; Shirai, T1
Furukawa, F; Mori, H; Mori, I; Nishikawa, A; Takahashi, M; Tanakamaru, Z1
Tucker, MJ1
Kushida, H; Nagao, M; Sone, H; Sugimura, T; Wakabayashi, K1
Brunnemann, KD; Hornby, AP; Stich, HF1

Other Studies

16 other study(ies) available for quinoxalines and Precancerous Conditions

ArticleYear
Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents.
    Oncotarget, 2017, Mar-21, Volume: 8, Issue:12

    Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinoma, Squamous Cell; Chemokines, CXC; Chemoprevention; Disease Models, Animal; Gene Expression Profiling; Lung Neoplasms; Mice; Pioglitazone; Precancerous Conditions; Quinoxalines; Sulfonamides; Thiazolidinediones; Transcriptome

2017
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:10

    Topics: Animals; Carcinogens; Diethylnitrosamine; DNA Adducts; Dose-Response Relationship, Drug; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2002
Lack of initiation activity in rat liver of low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
    Cancer letters, 2003, Feb-28, Volume: 191, Issue:1

    Topics: Animals; Biomarkers; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Synergism; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2003
Post-initiation inhibition of MeIQx hepatocarcinogenesis in rats by cysteine.
    Osaka city medical journal, 2003, Volume: 49, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cysteine; Deoxyguanosine; DNA; Genes, p53; Insulin-Like Growth Factor I; Liver Neoplasms, Experimental; Male; Nucleolus Organizer Region; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2003
Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3,8-dimethylimidazo [4,5-f ]quinoxaline (MeIQx) in rats.
    Cancer science, 2004, Volume: 95, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cell Proliferation; Colon; Colonic Neoplasms; Deoxyguanosine; Diet; DNA Adducts; Female; Glutathione Transferase; Humans; Lactation; Liver; Liver Neoplasms, Experimental; Male; Milk, Human; Placenta; Precancerous Conditions; Pregnancy; Quinoxalines; Rats; Rats, Inbred F344

2004
Existence of no-observed effect levels for 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline on hepatic preneoplastic lesion development in BN rats.
    Cancer letters, 2006, Jan-18, Volume: 231, Issue:2

    Topics: Animals; Carcinogens; Glutathione S-Transferase pi; Liver; Liver Neoplasms, Experimental; Male; No-Observed-Adverse-Effect Level; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred BN; Rats, Inbred F344

2006
Evidence of a threshold-effect for 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline liver carcinogenicity in F344/DuCrj rats.
    Toxicologic pathology, 2008, Volume: 36, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenoma, Liver Cell; Administration, Oral; Animal Feed; Animals; Carcinogens; Carcinoma, Hepatocellular; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Glutathione Transferase; Liver; Liver Neoplasms; Longevity; Male; No-Observed-Adverse-Effect Level; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2008
Dose-dependent induction of 8-hydroxyguanine and preneoplastic foci in rat liver by a food-derived carcinogen, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, at low dose levels.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:2

    Topics: Animals; Body Weight; Carcinogens; Diet; Glutathione Transferase; Guanine; Liver; Liver Neoplasms; Male; Organ Size; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

1996
An overview of cancer prevention.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1996, Volume: 5 Suppl 2

    Topics: beta Carotene; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Environmental Exposure; Humans; Imidazoles; Mutagens; Neoplasms; Neoplasms, Unknown Primary; Precancerous Conditions; Primary Prevention; Quinoxalines; Risk Factors

1996
Low-dose carcinogenicity of a heterocyclic amine, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline: relevance to risk assessment.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Animals; Carcinogens; Diet; Food Contamination; Glutathione Transferase; Humans; Liver; Male; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

1999
Protection against 12-O-tetradecanoylphorbol-13-acetate induced skin-hyperplasia and tumor promotion, in a two-stage carcinogenesis mouse model, by the 2,3-dimethyl-6(2-dimethylaminoethyl)-6H-indolo-[2,3-b]quinoxaline analogue of ellipticine.
    Chemico-biological interactions, 1999, Sep-30, Volume: 122, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Female; Hyperplasia; Indoles; Mice; Mice, Inbred SENCAR; Precancerous Conditions; Quinoxalines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1999
Modifying effects of propolis on MeIQx promotion of rat hepatocarcinogenesis and in a female rat two-stage carcinogenesis model after multiple carcinogen initiation.
    Nutrition and cancer, 2000, Volume: 37, Issue:2

    Topics: Alkylating Agents; Animals; Carcinogens; Diethylnitrosamine; Disease Models, Animal; Ethanol; Female; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Organ Size; Precancerous Conditions; Propolis; Quinoxalines; Random Allocation; Rats; Rats, Inbred F344; Water

2000
Essential similarities between spontaneous and MeIQx-promoted aberrant crypt foci in the F344 rat colon.
    Cancer letters, 2001, Oct-30, Volume: 172, Issue:2

    Topics: Animals; Carcinogens; Colonic Neoplasms; Genes, ras; Male; Mutagens; Mutation; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Quinoxalines; Rats; Rats, Inbred F344; Tumor Suppressor Protein p53

2001
Carcinogenic action of quinoxaline 1,4-dioxide in rats.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:1

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Fibrosarcoma; Hyperplasia; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Neuroectodermal Tumors, Primitive, Peripheral; Nose Neoplasms; Precancerous Conditions; Quinoxalines; Rats; Sex Factors

1975
Induction of preneoplastic lesions by a low dose of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in the livers of rats treated with carbon tetrachloride.
    Carcinogenesis, 1992, Volume: 13, Issue:5

    Topics: Animals; Carbon Tetrachloride; DNA; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

1992
Tobacco-specific nitrosamines in the saliva of Inuit snuff dippers in the Northwest Territories of Canada.
    Cancer letters, 1987, Volume: 37, Issue:1

    Topics: Canada; Cell Nucleus; Cotinine; Humans; Inuit; Male; Mouth Mucosa; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Precancerous Conditions; Quinoxalines; Saliva; Tobacco Use Disorder; Tobacco, Smokeless

1987