Page last updated: 2024-08-17

quinoxalines and Nerve Degeneration

quinoxalines has been researched along with Nerve Degeneration in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	23 (51.11)	18.2507
2000's	16 (35.56)	29.6817
2010's	6 (13.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bartlett, CA; Fitzgerald, M; Gavriel, N; Gopalasingam, G; Majimbi, M; McGonigle, T; Rodger, J; Toomey, LM	1
Bartlett, CA; Chiha, W; Fitzgerald, M; Giacci, MK; Harvey, AR; Hodgetts, SI; O'Hare Doig, RL; Smith, NM; Yates, NJ	1
Fehily, B; Fitzgerald, M; Gavriel, N; Giacci, MK; Gough, AH; Gray, CGG; Milbourn, HR; Toomey, LM	1
Agim, ZS; Cannon, JR; Cruz-Hernandez, A; McCabe, GP; Montenegro, PC; Rochet, JC	1
Bartlett, CA; Fitzgerald, M; Gopalasingam, G; Majimbi, M; Rodger, J; Toomey, LM	1
Antilla, JC; Bickford, PC; Engberg, ME; Hudson, CE; Kang, CW; Lambert, CS; Philpot, RM; Rowell, PP; Wecker, L; Zesiewicz, TA	1
Hashimoto, K; Nakamura, R; Suzuki, Y; Takagi, Y; Umemura, K	1
Ayala, GX; Tapia, R	1
Chung, EH; Egashira, N; Egawa, T; Fujiwara, M; Hatip-Al-Khatib, I; Irie, K; Iwasaki, K; Mishima, K	1
Avilés-Trigueros, M; García-Avilés, A; Lafuente, MP; Mayor-Torroglosa, S; Miralles de Imperial, J; Rodríguez, ME; Vidal-Sanz, M; Villegas-Pérez, MP	1
Aronica, E; Caraci, F; Caricasole, A; Caruso, A; Copani, A; Gaviraghi, G; Nicoletti, F; Rozemuller, AJ; Storto, M; Terstappen, GC	1
Camins, A; Canudas, AM; Folch, J; Jiménez, A; Jordà, EG; Pallàs, M; Rimbau, V; Verdaguer, E	1
Boriboun, C; Marks, JD; Wang, J	1
Barkoczy, J; Gigler, G; Gressens, P; Harsing, LG; Kapus, G; Kertesz, S; Levay, G; Medja, F; Spedding, M; Szenasi, G; Villa, P; Williamson, T	1
Avilés-Trigueros, M; de Imperial, JM; De la Villa, P; García-Avilés, A; López-Herrera, MP; Mayor-Torroglosa, S; Rodríguez, ME; Vidal-Sanz, M; Villegas-Pérez, MP	1
Fishbein, I; Segal, M	1
Hallböök, F; Lafuente, M; Lindqvist, N; Lönngren, U; Mayor, S; Näpänkangas, U; Vidal-Sanz, M	1
Montero, M; Møller, A; Nielsen, M; Noraberg, J; Rønn, LC; Zimmer, J	1
Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL	1
Massieu, L; Tapia, R	1
Brasko, J; Patrikios, P; Ross, DT	1
Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH	1
Massieu, L; Morales-Villagrán, A; Tapia, R	1
Choi, DW; Gwag, BJ; Koh, JY; Lobner, D	1
Hagberg, H; Lehmann, A; Orwar, O; Sandberg, M	1
Holmberg, L; Seiger, A; Sundström, E; von Euler, M	1
Couratier, P; Dumas, M; Hugon, J; Sindou, P; Vallat, JM	1
Bagetta, G; Dolly, JO; Nair, S; Nistico, G	1
Bernert, H; Turski, L	1
Deupree, DL; Dickman, E; Kirch, RD; Schloss, JV; Tang, XW; Wu, JY; Yarom, M	1
Collins, MA; Corso, TD; Mostafa, HM; Neafsey, EJ	1
Covey, DF; He, YY; Hsu, CY; Hu, R; Hu, Y; Yamada, KA	1
Bittigau, P; Bosch, F; Dikranian, K; Ikonomidou, C; Miksa, M; Olney, JW; Stefovska, V; Tenkova, TI; Turski, L; Vöckler, J	1
Schwartz, M; Wheeler, LA; Yoles, E	1
DeGiorgio, LA; DeGiorgio, N; Volpe, BT	1
Cagnotto, A; Carvelli, L; Comoletti, D; Manzoni, C; Mennini, T; Muzio, V; Rizzi, M; Vezzani, A	1
Arimura, K; Eto, K; Fukuyama, N; Miyamoto, K; Moriguchi, S; Murao, K; Nakanishi, H; Osame, M; Wakamiya, J	1
Abraham, KE; Brewer, KL; McGinty, JF	1
Chao, HM; Osborne, NN	1
Ahmed, FA; Chaudhary, P; Hegazy, K; Sharma, SC	1
Diemer, NH; Honoré, T; Johansen, FF; Jørgensen, MB; Sheardown, M	1
Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR	1
Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C	1
Miyamoto, T; Okada, Y; Sakurai, T	1
Facci, L; Leon, A; Skaper, SD	1

Reviews

1 review(s) available for quinoxalines and Nerve Degeneration

Article	Year
Limiting oxidative stress following neurotrauma with a combination of ion channel inhibitors. Discovery medicine, 2017, Volume: 23, Issue:129 Topics: Animals; Calcium; Central Nervous System; Humans; Imidazoles; Myelin Sheath; Nerve Degeneration; Oxidative Stress; Piperazines; Quinoxalines; Reactive Oxygen Species	2017

Other Studies

44 other study(ies) available for quinoxalines and Nerve Degeneration

Article	Year
Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection. Scientific reports, 2019, 10-25, Volume: 9, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Drug Therapy, Combination; Female; Imidazoles; Myelin Sheath; Nerve Degeneration; Optic Nerve; Optic Nerve Injuries; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Purinergic P2X7; Rosaniline Dyes	2019
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. BMC neuroscience, 2017, 08-14, Volume: 18, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Disease Models, Animal; Female; Imidazoles; Macrophages; Microglia; Nerve Degeneration; Nystagmus, Optokinetic; Optic Nerve Injuries; Oxidative Stress; Piperazines; Purinergic P2X Receptor Antagonists; Quinoxalines; Random Allocation; Ranvier's Nodes; Rats; Receptors, AMPA; Receptors, Purinergic P2X7	2017
Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons. Neurotoxicology, 2018, Volume: 65 Topics: Amines; Animals; Carbolines; Dopaminergic Neurons; Dose-Response Relationship, Drug; Harmine; Heterocyclic Compounds, 3-Ring; Mesencephalon; Molecular Structure; Nerve Degeneration; Neurites; Neurons; Primary Cell Culture; Quinolines; Quinoxalines; Rats	2018
Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection. Experimental brain research, 2019, Volume: 237, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Ectodysplasins; Female; Imidazoles; Ion Channels; Macrophages; Microfilament Proteins; Microglia; Nerve Degeneration; Nystagmus, Optokinetic; Oligodendrocyte Transcription Factor 2; Optic Nerve Injuries; Piperazines; Quinoxalines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Rosaniline Dyes; Tubulin	2019
Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia. Neuropharmacology, 2013, Volume: 73 Topics: Animals; Ataxia; Benzazepines; Cerebellum; Dose-Response Relationship, Drug; Gait; Male; Mecamylamine; Motor Activity; Nerve Degeneration; Neural Pathways; Niacinamide; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Olivary Nucleus; Postural Balance; Pyridines; Quinoxalines; Rats; Rotarod Performance Test; Varenicline	2013
Ability of NMDA and non-NMDA receptor antagonists to inhibit cerebral ischemic damage in aged rats. Brain research, 2003, Feb-21, Volume: 964, Issue:1 Topics: Aging; Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Telencephalon	2003
Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo. Neuropharmacology, 2003, Volume: 45, Issue:5 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Cell Count; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Drug Interactions; Electroencephalography; Epilepsy; Extracellular Space; Functional Laterality; Gene Expression; Glutamic Acid; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Piperazines; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stress, Physiological; Time Factors	2003
Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats. Brain research, 2004, Jan-02, Volume: 995, Issue:1 Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Reperfusion Injury	2004
Transient ischemia of the retina results in massive degeneration of the retinotectal projection: long-term neuroprotection with brimonidine. Experimental neurology, 2003, Volume: 184, Issue:2 Topics: Afferent Pathways; Animals; Axonal Transport; Brain Stem; Brimonidine Tartrate; Cholera Toxin; Eye; Female; Functional Laterality; Image Processing, Computer-Assisted; Immunohistochemistry; Ischemia; Mesencephalon; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Staining and Labeling	2003
Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jun-30, Volume: 24, Issue:26 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Dizocilpine Maleate; Gene Expression Regulation; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neurofibrillary Tangles; Neurons; Oligodeoxyribonucleotides; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Rats; RNA, Messenger; Signal Transduction; tau Proteins; Tumor Suppressor Protein p53; Wnt Proteins	2004
p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells. Brain research, 2004, Dec-31, Volume: 1030, Issue:2 Topics: Animals; Apoptosis; Benzodiazepines; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cerebellum; Cyclin-Dependent Kinase Inhibitor p21; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Neurons; Quinoxalines; Receptors, AMPA	2004
Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jul-13, Volume: 25, Issue:28 Topics: Animals; Animals, Newborn; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Hippocampus; Indazoles; Ion Transport; Mitochondria; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxadiazoles; Oxygen; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ruthenium Compounds; Thiazepines	2005
The effects of AMPA receptor antagonists in models of stroke and neurodegeneration. European journal of pharmacology, 2005, Sep-05, Volume: 519, Issue:1-2 Topics: Animals; Animals, Newborn; Anticonvulsants; Benzodiazepines; Brain; Brain Ischemia; Cell Survival; Chickens; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred Strains; Motor Neurons; Nerve Degeneration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Retina; Seizures; Stroke	2005
Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidine. Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:10 Topics: Animals; Brimonidine Tartrate; Electroretinography; Female; Ischemia; Ligation; Nerve Degeneration; Neuroprotective Agents; Ophthalmic Artery; Quinoxalines; Rats; Rats, Sprague-Dawley; Retina; Retinal Degeneration; Retinal Ganglion Cells; Retinal Vessels; Superior Colliculi; Time Factors; Visual Pathways	2005
Miniature synaptic currents become neurotoxic to chronically silenced neurons. Cerebral cortex (New York, N.Y. : 1991), 2007, Volume: 17, Issue:6 Topics: Action Potentials; Anesthetics, Local; Animals; Apoptosis; Calcium; Cells, Cultured; Dendritic Spines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synaptic Transmission; Tetrodotoxin	2007
The growth factor response in ischemic rat retina and superior colliculus after brimonidine pre-treatment. Brain research bulletin, 2006, Dec-11, Volume: 71, Issue:1-3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Axons; Brain Ischemia; Brimonidine Tartrate; Cytoprotection; Disease Models, Animal; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Growth Factor; Retinal Ganglion Cells; RNA, Messenger; Superior Colliculi; Up-Regulation	2006
Neuroprotective effects of the AMPA antagonist PNQX in oxygen-glucose deprivation in mouse hippocampal slice cultures and global cerebral ischemia in gerbils. Brain research, 2007, Oct-26, Volume: 1177 Topics: Animals; Body Temperature; Cell Death; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fluoresceins; Gerbillinae; Glucose; Hippocampus; Hypoxia, Brain; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Nerve Degeneration; Neuroprotective Agents; Organ Culture Techniques; Organic Chemicals; Quinoxalines; Receptors, AMPA; Tolonium Chloride	2007
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline. Brain research, 1993, Nov-05, Volume: 627, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar	1993
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo. Neuroscience, 1994, Volume: 59, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate	1994
The AMPA antagonist NBQX protects thalamic reticular neurons from degeneration following cardiac arrest in rats. Brain research, 1995, Jun-12, Volume: 683, Issue:1 Topics: Animals; Excitatory Amino Acid Antagonists; Heart Arrest; Male; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, AMPA; Reticular Formation; Thalamus	1995
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate	1993
Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study. Journal of neurochemistry, 1995, Volume: 64, Issue:5 Topics: Animals; Cell Death; Choline; Choline O-Acetyltransferase; Corpus Striatum; Dicarboxylic Acids; Dizocilpine Maleate; Extracellular Space; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar	1995
Potentiated necrosis of cultured cortical neurons by neurotrophins. Science (New York, N.Y.), 1995, Apr-28, Volume: 268, Issue:5210 Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Mice; N-Methylaspartate; Necrosis; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neurotrophin 3; Quinoxalines; Receptors, AMPA	1995
Cysteine sulphinate and cysteate: mediators of cysteine toxicity in the neonatal rat brain? The European journal of neuroscience, 1993, Oct-01, Volume: 5, Issue:10 Topics: Amino Acids; Animals; Animals, Newborn; Brain; Cerebral Cortex; Cysteic Acid; Cysteine; Dizocilpine Maleate; Female; Male; Nerve Degeneration; Neurons; Neurotoxins; Neurotransmitter Agents; Organ Specificity; Quinoxalines; Rats; Rats, Sprague-Dawley	1993
NBQX, a competitive non-NMDA receptor antagonist, reduces degeneration due to focal spinal cord ischemia. Experimental neurology, 1994, Volume: 129, Issue:1 Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Ischemia; Lasers; Nerve Degeneration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reference Values; Spinal Cord; Time Factors	1994
Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors. Lancet (London, England), 1993, Jan-30, Volume: 341, Issue:8840 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Humans; Middle Aged; Motor Neurons; Nerve Degeneration; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid	1993
Hippocampal damage produced in rats by alpha-dendrotoxin--a selective K+ channel blocker--involves non-NMDA receptor activation. Neurochemistry international, 1994, Volume: 24, Issue:1 Topics: Animals; Elapid Venoms; Electroencephalography; Hippocampus; Male; Nerve Degeneration; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Seizures	1994
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11 Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Time Factors; Wounds, Nonpenetrating	1996
Studies of NMDA- and non-NMDA-mediated neurotoxicity in cultured neurons. Neurochemistry international, 1996, Volume: 29, Issue:3 Topics: Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Kainic Acid; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	1996
Brain neuronal degeneration caused by episodic alcohol intoxication in rats: effects of nimodipine, 6,7-dinitro-quinoxaline-2,3-dione, and MK-801. Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:1 Topics: Alcoholic Intoxication; Animals; Brain; Calcium Channel Blockers; Dentate Gyrus; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Nimodipine; Quinoxalines; Rats; Rats, Sprague-Dawley	1998
The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury. Annals of neurology, 1998, Volume: 43, Issue:5 Topics: Animals; Benzothiadiazines; Brain Ischemia; Cells, Cultured; Diazoxide; Diuretics; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Nerve Degeneration; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Sodium Chloride Symporter Inhibitors	1998
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science (New York, N.Y.), 1999, Jan-01, Volume: 283, Issue:5398 Topics: Animals; Apoptosis; Brain; Calcium Channel Blockers; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Haloperidol; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron; Muscarinic Antagonists; Nerve Degeneration; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Scopolamine	1999
Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration. Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:1 Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Axons; Brimonidine Tartrate; Cell Count; Cell Survival; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Retinal Ganglion Cells; Timolol; Yohimbine	1999
Dizocilpine maleate, MK-801, but not 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline, NBQX, prevents transneuronal degeneration of nigral neurons after neurotoxic striatal-pallidal lesion. Neuroscience, 1999, Volume: 90, Issue:1 Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Globus Pallidus; Ibotenic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Substantia Nigra	1999
Biochemical and pharmacological evidence of a functional role of AMPA receptors in motor neuron dysfunction in mnd mice. The European journal of neuroscience, 1999, Volume: 11, Issue:5 Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Antibodies; Autoradiography; Blotting, Western; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Mutant Strains; Motor Neurons; Nerve Degeneration; Neurotoxins; Quinoxalines; Receptors, AMPA; Spinal Cord; Tritium	1999
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity. Brain research, 2001, May-18, Volume: 901, Issue:1-2 Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Glycoproteins; Mercury Poisoning, Nervous System; Methylmercury Compounds; Nerve Degeneration; Neurons; Nitrates; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine	2001
The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury. Neuroscience, 2001, Volume: 104, Issue:3 Topics: Animals; Behavior, Animal; Dynorphins; Enkephalins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Grooming; Indans; Male; Nerve Degeneration; Neurons; Neurotoxins; Opioid Peptides; Pain; Pain Measurement; Protein Precursors; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; RNA, Messenger; Spinal Cord; Spinal Cord Injuries	2001
Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors. Brain research, 2001, Jun-15, Volume: 904, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds; Brimonidine Tartrate; Calbindin 2; Cell Death; Choline O-Acetyltransferase; Clonidine; Electroretinography; Heptanes; Imidazoline Receptors; Immunohistochemistry; Membrane Potentials; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Reperfusion Injury; Retina; Retinal Ganglion Cells; S100 Calcium Binding Protein G; Yohimbine	2001
Neuroprotective effect of alpha(2) agonist (brimonidine) on adult rat retinal ganglion cells after increased intraocular pressure. Brain research, 2001, Sep-21, Volume: 913, Issue:2 Topics: Adrenergic alpha-Antagonists; Age Factors; Animals; Brimonidine Tartrate; Cell Count; Cell Survival; Disease Models, Animal; Female; Glaucoma; Intraocular Pressure; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Retinal Ganglion Cells; Time Factors	2001
Protection against ischemic hippocampal CA1 damage in the rat with a new non-NMDA antagonist, NBQX. Acta neurologica Scandinavica, 1992, Volume: 86, Issue:1 Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Cell Count; Hippocampus; Male; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1992
Excitotoxicity in the embryonic chick spinal cord. Annals of neurology, 1991, Volume: 30, Issue:6 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord	1991
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains	1991
Masking effect of NMDA receptor antagonists on the formation of long-term potentiation (LTP) in superior colliculus slices from the guinea pig. Brain research, 1990, Jun-04, Volume: 518, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Denervation; Dibenzocycloheptenes; Dipeptides; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; Magnesium; Mice; Nerve Degeneration; Optic Nerve; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Visual Cortex	1990
Hypoglycemic neurotoxicity in vitro: involvement of excitatory amino acid receptors and attenuation by monosialoganglioside GM1. Neuroscience, 1990, Volume: 37, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebellum; G(M1) Ganglioside; Gangliosides; Hypoglycemia; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate	1990