Page last updated: 2024-08-17

quinoxalines and Leukemia, Myeloid, Acute

quinoxalines has been researched along with Leukemia, Myeloid, Acute in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bonnet, PA; Deleuze-Masquefa, C; El Hajj, H; El Hajj, R; El Sabban, M; Hamie, M; Hleihel, R; Jishi, B; Skayneh, H1
Chen, X; Chen, Y; Fan, Y; Li, D; Luo, Y; Wang, T; Wu, L; Xu, J; Zhang, L; Zhuang, Y1
Bosman, MC; Quax, WJ; Schuringa, JJ; Vellenga, E1
Bensinger, D; Göring, S; Naumann, EC; Schmidt, B1
Bastie, JN; Delva, L; Nguyen, CH; Quéré, R; Saint-Paul, L1
Berthier, CP; Bonnet, PA; Deleuze-Masquefa, C; El Hajj, HA; Hamie, MH; Hleihel, RS; Karam, MM; Nabbouh, AI; Saliba, JL; Tawil, NM; Wu, HJM1
Bruserud, Ø; Ersvaer, E; Hatfield, KJ; Kittang, AO; Lassalle, P; Reikvam, H1
Cool, RH; Knapper, S; Natoni, A; O'Dwyer, M; O'Reilly, A; Quax, WJ; Reeve, J; Reis, CR; Samali, A; Serrano, L; Szegezdi, E; van der Sloot, AM1

Other Studies

8 other study(ies) available for quinoxalines and Leukemia, Myeloid, Acute

ArticleYear
EAPB0503, an Imidazoquinoxaline Derivative Modulates SENP3/ARF Mediated SUMOylation, and Induces NPM1c Degradation in NPM1 Mutant AML.
    International journal of molecular sciences, 2022, Mar-22, Volume: 23, Issue:7

    Topics: Animals; Cysteine Endopeptidases; Humans; Leukemia, Myeloid, Acute; Mice; Mutation; Nuclear Proteins; Nucleophosmin; Quinoxalines; Sumoylation

2022
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
    Molecular cancer research : MCR, 2019, Volume: 17, Issue:3

    Topics: Animals; DNA Damage; DNA Repair; Feedback, Physiological; Gene Knockdown Techniques; Heterografts; Humans; Imidazoles; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Promoter Regions, Genetic; Quinoxalines; Transcription Factor RelA

2019
Bortezomib sensitivity of acute myeloid leukemia CD34(+) cells can be enhanced by targeting the persisting activity of NF-κB and the accumulation of MCL-1.
    Experimental hematology, 2013, Volume: 41, Issue:6

    Topics: Antigens, CD34; Boronic Acids; Bortezomib; Coculture Techniques; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Humans; I-kappa B Kinase; Imidazoles; Leukemia, Myeloid, Acute; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Primary Cell Culture; Protease Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Quinoxalines; Recombinant Proteins; RNA, Small Interfering; Stromal Cells; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2013
Computer-guided design, synthesis, and biological evaluation of quinoxalinebisarylureas as FLT3 inhibitors.
    ChemMedChem, 2015, Volume: 10, Issue:3

    Topics: Animals; Drug Design; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Molecular Docking Simulation; Protein Kinase Inhibitors; Quinoxalines; Zebrafish

2015
[CD45 phosphatase, a relevant target for the treatment of acute myeloid leukemia].
    Medecine sciences : M/S, 2016, Volume: 32, Issue:12

    Topics: Antineoplastic Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Molecular Targeted Therapy; Quinoxalines; Signal Transduction

2016
Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
    Cancer, 2017, 05-01, Volume: 123, Issue:9

    Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleolus; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; Flow Cytometry; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Mice; Microscopy, Confocal; Mutant Proteins; Mutation; Nuclear Proteins; Nucleophosmin; Phosphorylation; Poly(ADP-ribose) Polymerases; Quinoxalines; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2017
Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells: studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release.
    Expert opinion on investigational drugs, 2010, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiopoietin-1; Angiopoietin-2; Antibodies; Boronic Acids; Bortezomib; Cell Proliferation; Cells, Cultured; Coculture Techniques; Endothelial Cells; Female; Fibroblasts; Hepatocyte Growth Factor; Humans; Imidazoles; Interleukin-8; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Osteoblasts; Proteoglycans; Pyrazines; Quinoxalines; Receptor Cross-Talk; Receptor, TIE-2; Signal Transduction

2010
Targeting AML through DR4 with a novel variant of rhTRAIL.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Cell Line, Tumor; Epidermal Cells; Female; Humans; Imidazoles; Keratinocytes; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Membrane Potentials; Middle Aged; Quinoxalines; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand

2011