Page last updated: 2024-08-17

quinoxalines and Disease Models, Animal

quinoxalines has been researched along with Disease Models, Animal in 285 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (285)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (0.70)	18.7374
1990's	32 (11.23)	18.2507
2000's	102 (35.79)	29.6817
2010's	132 (46.32)	24.3611
2020's	17 (5.96)	2.80

Authors

Authors	Studies
Balitza, AE; Barnett, SF; Bilodeau, MT; Defeo-Jones, D; Hartman, GD; Haskell, K; Hoffman, JM; Huber, HE; Jones, RE; Leander, K; Manley, PJ; Robinson, RG; Smith, AM	1
Chen, X; Chen, Z; Dai, G; Gan, Y; He, Y; Li, B; Ru, F; Xia, W; Zhang, B	1
Basta, MD; Paulson, H; Walker, JL	1
Xia, H; You, F; Zhang, Z	1
Gao, D; Liu, D; Ma, X; Sun, M; Xu, D; Yu, H	1
Edwards, CM; Edwards, JR; Gooding, S; Javaid, MK; Leung, SK; Lwin, ST; Nador, G; Olechnowicz, SWZ; Ramasamy, K; Rao, SR; Weivoda, MM	1
Chen, J; Hua, Y; Keep, RF; Tan, X; Xi, G	1
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; Wang, YL; Wang, YN; Wáng, YXJ; Wang, Z; Wang, ZF; Wang, ZY; Waning, B; Warner, JM; Washington, SL; Watson, AK; Wei, B; Wei, C; Wei, F; Wei, X; Wei, Y; Wemhoff, AP; Wen, Z; Weng, TT; Wesdemiotis, C; Wheeler, DA; Wildner, M; Wilson, BK; Wirth, LJ; Wissler, M; Wu, F; Wu, G; Wu, J; Wu, KH; Wu, MC; Wu, P; Wu, PK; Wu, S; Wu, W; Wu, X; Wu, XP; Wu, Y; Wyatt, E; Wyllie, S; Xia, Y; Xiao, BH; Xiao, SZ; Xiao, W; Xiao, X; Xiao, Z; Xie, D; Xie, K; Xie, X; Xie, Y; Xie, YF; Xin, S; Xin, Z; Xing, Q; Xing, WQ; Xiong, D; Xiong, X; Xu, C; Xu, D; Xu, F; Xu, G; Xu, H; Xu, J; Xu, JY; Xu, L; Xu, N; Xu, W; Xu, X; Xu, Y; Xu, YM; Xue, H; Xue, J; Xue, Z; Yan, R; Yan, SQ; Yan, W; Yan, X; Yan, Z; Yang, C; Yang, D; Yang, F; Yang, FC; Yang, G; Yang, J; Yang, M; Yang, P; Yang, Q; Yang, R; Yang, S; Yang, SJ; Yang, TWW; Yang, X; Yang, Y; Yang, Z; Yao, C; Yao, L; Yao, LP; Yao, M; Yao, T; Yao, W; Yao, Y; Yaseen, T; Yazdani, V; Ye, J; Ye, S; Yerys, BE; Yi, HWL; Yi, JL; Yin, F; Yin, J; Yin, Y; Yin, Z; Yong, ZP; Yongli, S; Yoo, JS; Yoshikawa, N; You, Q; Yu, B; Yu, CQ; Yu, H; Yu, HG; Yu, J; Yu, L; Yu, Q; Yu, X; Yu, Y; Yu, YK; Yu, Z; Yuan, Q; Yuan, R; Yuan, W; Yuan, X; Yuan, Y; Zager, RA; Zagozdzon, A; Zaller, N; Zang, YP; Zappi, ME; Zelikoff, JT; Zeman, T; Zhai, X; Zhan, P; Zhang, B; Zhang, C; Zhang, G; Zhang, H; Zhang, HB; Zhang, J; Zhang, JS; Zhang, L; Zhang, M; Zhang, Q; Zhang, RX; Zhang, S; Zhang, T; Zhang, W; Zhang, WH; Zhang, X; Zhang, XX; Zhang, Y; Zhang, YQ; Zhang, YW; Zhang, Z; Zhang, ZH; Zhao, D; Zhao, FL; Zhao, K; Zhao, L; Zhao, M; Zhao, R; Zhao, S; Zhao, W; Zhao, WG; Zhao, X; Zhao, Y; Zheng, G; Zheng, J; Zheng, S; Zheng, W; Zheng, Y; Zheng, YG; Zhong, Z; Zhou, C; Zhou, D; Zhou, H; Zhou, HY; Zhou, L; Zhou, Q; Zhou, X; Zhou, Y; Zhou, YL; Zhou, Z; Zhu, J; Zhu, L; Zhu, N; Zhu, X; Zhu, XF; Zhu, Y; Zhu, Z	1
Andres, AM; Germano, JF; Gottlieb, RA; Huang, C; Mentzer, RM; Piplani, H; Saadaeijahromi, H; Sin, J; Song, Y; Stotland, A; Taylor, DJR; Tucker, KC	1
Fujita, Y; Hashimoto, K; Iwata, M; Muneoka, K; Oda, Y; Shirayama, Y	1
Chen, L; Cheng, S; Li, B; Lin, Z; Wang, M; Wang, W; Yao, M; Yin, Q; Zhang, Y	1
Heath, BR; Hong, L; Lei, YL; Ljungman, M; Lu, T; Neamati, N; Shrestha, B; Tang, J	1
Aliev, OI; Anfinogenova, YJ; Atochin, DN; Chernysheva, GA; Khlebnikov, AI; Osipenko, AN; Plotnikov, MB; Schepetkin, IA; Sherstoboev, EY; Smolyakova, VI; Trofimova, ES	1
Jin, R; Li, G; Liu, S; Wang, M; Zhong, W	1
Bauer, MR; Boehm, SL; Garcy, DP	1
Funahashi, H; Haruta-Tsukamoto, A; Ishida, Y; Miyahara, Y; Nishimori, T	1
Cho, SS; Ki, SH; Kim, KM	1
Bai, L; Dai, E; Han, L; Kang, R; Liu, J; Tang, D; Xie, Y; Zeh, HJ	1
Hu, MH; Lin, JH	1
Chen, Z; Guo, Y; Hou, Z; Li, F; Liu, H; Wang, N; Wang, Y; Xue, X; Zhou, Y	1
Aceves, A; Andres, AM; Aniag, M; de Freitas Germano, J; Gottlieb, RA; Huang, C; Mentzer, RM; Piplani, H; Sharma, A; Stastna, M; Van Eyk, JE	1
Jacobs, KM; Jin, X; Povlishock, JT; Vascak, M	1
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Ardissone, V; Camps, M; Chabert, C; Cirillo, R; Ferrandi, C; Françon, B; Gillieron, C; Gretener, D; Hirsch, E; Ji, H; Leroy, D; Martin, T; Perrin, D; Rintelen, F; Rommel, C; Rückle, T; Schwarz, MK; Shaw, J; Vitte, PA; Wymann, MP	1
Ben-Ari, Y; Crépel, V; Epsztein, J; Jorquera, I; Represa, A	1
An, TH; Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH	1
Dong, RG; Flavahan, NA; Flavahan, S; Krajnak, K; Welcome, D	1
Hara, H; Kodama, M; Kuroda, S; Matsumoto, Y; Wake, Y; Yamada, N	1
Barrett, JE; Dunlop, J; Harrison, BL; Mazandarani, H; Rosenzweig-Lipson, S; Sabalski, J; Sabb, A; Stack, G; Welmaker, G; Zhang, J	1
Carta, M; Mameli, M; Valenzuela, CF	1
Amato, A; Feo, S; Mulè, F; Serio, R; Zizzo, MG	1
Aloni, E; Bakalash, S; Ben Simon, GJ; Rosner, M	1
Kamata, K; Kobayashi, T; Matsumoto, T	1
Alcala, SR; Danylkova, NO; McLoon, LK; Pomeranz, HD	1
Hallböök, F; Lafuente, M; Lindqvist, N; Lönngren, U; Mayor, S; Näpänkangas, U; Vidal-Sanz, M	1
Grossman, Y; Mor, A	1
Ali, C; Clemente, D; Correa, F; Docagne, F; Guaza, C; Hernangómez, M; Loría, F; Mestre, L; Muñetón, V; Vivien, D	1
Arnolda, LF; Holobotovskyy, VV; Malik, V; McKitrick, DJ; Phillips, JK	1
Richter, A; Sander, SE	1
Albani, M; Gougoulias, N; Kouvelas, D	1
Hassam, R; Jones, S; Kung, VW; Morton, AJ	1
Aktaş, Z; Akyürek, N; Gürelik, G; Hasanreisoğlu, B; Onol, M	1
Malakul, W; Suvitayavat, W; Thirawarapan, S; Woodman, OL	1
Cuvelier, C; Demetter, P; Lefebvre, RA; Timmermans, JP; Van Crombruggen, K; Van Nassauw, L	1
Brito, GA; Gadelha, GG; Garcia, JA; Lima, SJ; Medeiros, JV; Ribeiro, RA; Santos, AA; Soares, PM; Souza, MH	1
Chen, G; Dow, ER; Du, J; Gould, TD; Manji, HK; O'Donnell, KC	1
Avni, I; Barak, A; Ben-Shoshan, J; George, J; Levkovitch-Verbin, H; Luboshits, G; Rosner, M; Schwartz, S; Ziv, H	1
Akil, O; Clause, A; Edwards, RH; Glowatzki, E; Grant, L; Kandler, K; Lustig, LR; Noebels, JL; Seal, RP; Weber, CM; Yi, E; Yoo, J	1
Cao, Z; Chen, S; Fan, J; Li, Y; Owyang, C; Wu, X; Zhang, R	1
Fukushima, M; Kano, T; Katayama, Y; Koshinaga, M; Suma, T	1
Arnal, JF; Breton-Douillon, M; Fougerat, A; Gayral, S; Gourdy, P; Hirsch, E; Laffargue, M; Perret, B; Rommel, C; Rückle, T; Salles, JP; Schambourg, A; Schwarz, MK; Wymann, MP	1
Brock, SC; Tonussi, CR	1
Harris, HE; Klareskog, L; Thi Ngoc, DD; Westman, E	1
Gerardy-Schahn, R; Pekcec, A; Potschka, H; Weinhold, B	1
Björklund, U; Holmdahl, R; Hultqvist, M; Nandakumar, KS	1
Hernández, M; Urcola, JH; Vecino, E	1
Awatramani, GB; Balya, D; Busskamp, V; Cepko, CL; Kim, DS; Lagali, PS; Münch, TA; Roska, B	1
Auberson, YP; Fantin, M; Morari, M	1
Catarzi, D; Ciampi, O; Colotta, V; Filacchioni, G; Lenzi, O; Martini, C; Morizzo, E; Moro, S; Pedata, F; Pugliese, AM; Traini, C; Trincavelli, L; Varano, F	1
Ilijic, E; Surmeier, DJ; Taverna, S	1
Kutchak, SN; Padeĭskaia, EN; Shipilova, LD	1
Akimova, AIa; Buianov, VM; Egiev, VN; Gritskova, IV	1
Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E	1
de Villiers, AS; Jaffer, A; Russell, VA; Sagvolden, T; Searson, A; Taljaard, JJ	1
Donevan, SD; Rogawski, MA; Yamaguchi, S	1
Gaspary, HL; Graham, SH; Simon, RP	1
Andiné, P; Diemer, NH; Gilland, E; Hagberg, H	1
Sluka, KA; Westlund, KN	1
Greenamyre, JT	1
al-Zubaidy, ZA; Chapman, AG; Meldrum, BS; Smith, SE	1
Bernert, H; Turski, L	1
Marshall, JF; Schuller, JJ	1
Bullock, R; Di, X	1
Hicks, C; O'Neill, MJ; Ward, M	1
Jensen, FE; Wang, C	1
Umemura, K	1
Kristiansen, E; Meyer, O; Thorup, I	1
Marriott, R; Teng, YD; Wrathall, JR	1
Brennan, TJ; Umali, E; Zahn, PK	1
Ichiki, C; Kawasaki-Yatsugi, S; Minematsu, K; Shimizu-Sasamata, M; Takahashi, M; Toya, T; Yamaguchi, T; Yatsugi, S	1
Heinemann, U; Müller, W; Schuchmann, S	1
Nakamichi, T	1
Behl, B; Hofmann, HP; Löscher, W; Potschka, H; Szabo, L; Treiber, HJ; Wlaź, P	1
Ikeda, Y; Kondo, K; Takamatsu, H; Umemura, K	1
Schwartz, M; Wheeler, LA; Yoles, E	1
Acklin, P; Auberson, YP; Bischoff, S; Moretti, R; Ofner, S; Schmutz, M; Veenstra, SJ	1
Edward, DP; Lark, KK; Pasha, AS; Yan, X	1
Bigge, CF; Boxer, PA; Iadecola, C; Kupina, NC; Schielke, GP; Welty, DF	1
Chen, J; Li, H; Li, Z; Luo, C; Zheng, J	1
Groom, A; Smith, T; Turski, L; Zhu, B	1
Pitt, D; Raine, CS; Werner, P	2
Folbergrová, J; Haugvicová, R; Mares, P	1
Bennett, AD; Everhart, AW; Hulsebosch, CE	1
Kawabe, A; Maruoka, Y; Nakamura, M; Ohtani, K; Tanaka, H; Yasuda, H	1
Burton, FH; Campbell, KM; McGrath, MJ; Parks, CR	1
Bertram, EH; Mangan, PS; Scott, CA; Williamson, JM	1
Allie, S; Russell, V; Wiggins, T	1
Hirose, M; Kawabe, M; Kimoto, N; Lin, C; Sano, M; Shirai, T	1
Didion, SP; Faraci, FM; Heistad, DD	1
Lagrèze, WA	1
Brenner, M; Kubiak, R; Palluk, R; Weckesser, G; Weiser, T; Wienrich, M	1
Ahmed, FA; Chaudhary, P; Hegazy, K; Sharma, SC	1
Grehn, F	1
Cunha, FQ; Prado, WA; Schiavon, VF	1
Benozzi, J; Campanelli, JL; Nahum, LP; Rosenstein, RE	1
Baba, AI; Suteu, E; Toader, S	1
Cao, Z; Clark, S; Hosford, DA; Huin, A; Lin, FH; Morrisett, RA; Wilson, WA	1
Ammendola, D; De Sarro, A; De Sarro, G; Trimarchi, GR	1
Gill, R; Lodge, D; Nordholm, L	1
Honoré, T; Jähnig, P; Jenner, P; Kunow, M; Lange, KW; Löschmann, PA; Marsden, CD; Rettig, KJ; Turski, L; Wachtel, H	1

Reviews

8 review(s) available for quinoxalines and Disease Models, Animal

Article	Year
The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1 Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus	2016
Emerging roles of ferroptosis in liver pathophysiology. Archives of pharmacal research, 2020, Volume: 43, Issue:10 Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexylamines; Deferoxamine; Disease Models, Animal; Disease Progression; Fatty Acids, Unsaturated; Ferroptosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Spiro Compounds	2020
T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics. Cell death & disease, 2018, 10-24, Volume: 9, Issue:11 Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Drug Discovery; Humans; Indolizines; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Targeted Therapy; Neoplasms; Quinolones; Quinoxalines; Thiophenes; Treatment Outcome	2018
Comparative pathophysiology, toxicology, and human cancer risk assessment of pharmaceutical-induced hibernoma. Toxicology and applied pharmacology, 2013, Dec-15, Volume: 273, Issue:3 Topics: Animals; Benzazepines; Carcinogenicity Tests; Disease Models, Animal; Humans; Hydromorphone; Lipoma; Mutagenicity Tests; Neoplasms; Phentolamine; Piperidines; Pyrimidines; Pyrroles; Quinoxalines; Rats; Risk Assessment; Varenicline	2013
YM872: a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist. CNS drug reviews, 2002,Winter, Volume: 8, Issue:4 Topics: Animals; Brain Ischemia; Cats; Clinical Trials, Phase I as Topic; Disease Models, Animal; Excitatory Amino Acid Antagonists; Humans; Imidazoles; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Quinoxalines; Rats; Receptors, AMPA; Solubility; Stroke	2002
Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson's disease. Journal of neural transmission. General section, 1993, Volume: 91, Issue:2-3 Topics: Animals; Antiparkinson Agents; Basal Ganglia; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haplorhini; Humans; Mice; MPTP Poisoning; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Quinoxalines; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1993
Hypoxia-induced hyperexcitability in vivo and in vitro in the immature hippocampus. Epilepsy research, 1996, Volume: 26, Issue:1 Topics: Age Factors; Animals; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Electrophysiology; Epilepsy, Temporal Lobe; Hippocampus; Hypoxia; In Vitro Techniques; Lorazepam; Quinoxalines; Rats	1996
[A novel photochemical model of the middle cerebral artery for thrombosis research and evaluation of anti-thrombotic agents]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 109, Issue:4 Topics: Animals; Disease Models, Animal; Drug Evaluation; Fibrinolytic Agents; Fluorescent Dyes; Glutamic Acid; Intracranial Embolism and Thrombosis; Light; Magnetic Resonance Imaging; Nicotinic Acids; Photochemistry; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Rose Bengal	1997

Trials

1 trial(s) available for quinoxalines and Disease Models, Animal

Article

Year

The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

2016

Other Studies

277 other study(ies) available for quinoxalines and Disease Models, Animal

Article	Year
Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. Bioorganic & medicinal chemistry letters, 2008, Jun-01, Volume: 18, Issue:11 Topics: Animals; Antineoplastic Agents; Combinatorial Chemistry Techniques; Disease Models, Animal; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Naphthyridines; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship	2008
Liproxstatin-1 attenuates unilateral ureteral obstruction-induced renal fibrosis by inhibiting renal tubular epithelial cells ferroptosis. Cell death & disease, 2021, 09-11, Volume: 12, Issue:9 Topics: Animals; Carbolines; Cell Death; Cell Line; Cell Proliferation; Cell Shape; Collagen; Disease Models, Animal; Epithelial Cells; Ferroptosis; Fibrosis; Humans; Iron; Kidney Tubules; Lipid Peroxidation; Male; Mice, Inbred C57BL; Myofibroblasts; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Spiro Compounds; Ureteral Obstruction	2021
The local wound environment is a key determinant of the outcome of TGFβ signaling on the fibrotic response of CD44 Experimental eye research, 2021, Volume: 213 Topics: Actins; Animals; Blotting, Western; Capsule Opacification; Cataract Extraction; Cell Proliferation; Chick Embryo; Collagen Type I; Disease Models, Animal; Fibronectins; Fibrosis; Hyaluronan Receptors; Imidazoles; Integrin alphaVbeta3; Microscopy, Fluorescence; Myofibroblasts; Posterior Capsule of the Lens; Postoperative Complications; Pyrazoles; Pyrroles; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Transforming Growth Factor beta; Wound Healing	2021
Inhibiting ACSL1-Related Ferroptosis Restrains Murine Coronavirus Infection. Viruses, 2021, 11-28, Volume: 13, Issue:12 Topics: Animals; Coenzyme A Ligases; Coronavirus Infections; Cytokines; Disease Models, Animal; Ferroptosis; Genes, Viral; Lung Injury; Macrophages; Mice; Mice, Inbred C57BL; Murine hepatitis virus; Quinoxalines; RAW 264.7 Cells; Spiro Compounds; Toll-Like Receptor 4; Virus Replication	2021
Inhibition of TRPA1 and IL-6 signal alleviates neuropathic pain following chemotherapeutic bortezomib. Physiological research, 2019, 10-25, Volume: 68, Issue:5 Topics: Acetanilides; Analgesics; Animals; Bortezomib; Disease Models, Animal; Ganglia, Spinal; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Male; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Threshold; Phosphorylation; Proteasome Inhibitors; Purines; Pyrazines; Quinoxalines; Rats, Sprague-Dawley; Receptors, Interleukin-6; Sensory Receptor Cells; Signal Transduction; TRPA1 Cation Channel	2019
Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment. Scientific reports, 2019, 10-02, Volume: 9, Issue:1 Topics: Adiponectin; Animals; Bone Marrow; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mice; Multiple Myeloma; Nerve Growth Factor; Neuroglia; NF-kappa B; Osteoblasts; Pain; Peptides; Piperidines; Quinoxalines; Stromal Cells; Tumor Microenvironment; Tumor Necrosis Factor-alpha	2019
Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage. Stroke, 2020, Volume: 51, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Cerebral Intraventricular Hemorrhage; Choroid Plexus; Disease Models, Animal; Ependyma; Female; Hydrocephalus; Hylobatidae; Inflammation; Injections, Intraventricular; Macrophage Activation; Macrophages; Male; Minocycline; Neutrophils; Peroxiredoxins; Quinoxalines; Rats; Rats, Sprague-Dawley	2020
Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover. Scientific reports, 2020, 05-19, Volume: 10, Issue:1 Topics: Animals; Biomarkers; Cell Line; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Heart Function Tests; Male; Mice; Mice, Knockout; Mitochondria, Heart; Mitophagy; Myocardial Infarction; Myocytes, Cardiac; Quinoxalines; Rats; Ubiquitin-Protein Ligases; Ventricular Remodeling	2020
Allopregnanolone induces antidepressant-like effects through BDNF-TrkB signaling independent from AMPA receptor activation in a rat learned helplessness model of depression. Behavioural brain research, 2020, 07-15, Volume: 390 Topics: Animals; Antidepressive Agents; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Helplessness, Learned; Male; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; Signal Transduction	2020
Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma. Molecular medicine reports, 2020, Volume: 22, Issue:2 Topics: Animals; Apoptosis; Benzamides; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glycine; HSP90 Heat-Shock Proteins; Humans; Imidazoles; Indazoles; Microwaves; Osteosarcoma; Quinoxalines; Rabbits; Radiofrequency Ablation; Transforming Growth Factor beta1; Tumor Burden	2020
Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer. Theranostics, 2020, Volume: 10, Issue:15 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrazines; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Quinoxalines; RNA, Antisense; Up-Regulation	2020
Neuroprotective Effects of a Novel Inhibitor of c-Jun N-Terminal Kinase in the Rat Model of Transient Focal Cerebral Ischemia. Cells, 2020, 08-08, Volume: 9, Issue:8 Topics: Animals; Brain Ischemia; Disease Models, Animal; Hippocampus; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Neuroprotective Agents; Oximes; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Reperfusion Injury	2020
Inhibition of PI3Kγ by AS605240 plus low-dose tissue plasminogen activator (tPA) combination improves thrombolytic therapy in a rat model of embolic stroke. Neuroscience letters, 2020, 11-01, Volume: 738 Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Embolic Stroke; Fibrinolytic Agents; Male; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome	2020
Systemic Administration of the AMPA Receptor Antagonist, NBQX, Reduces Alcohol Drinking in Male C57BL/6J, But Not Female C57BL/6J or High-Alcohol-Preferring, Mice. Alcoholism, clinical and experimental research, 2020, Volume: 44, Issue:11 Topics: Alcohol Drinking; Animals; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Motor Activity; Quinoxalines; Receptors, AMPA; Sex Factors	2020
Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice. Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4 Topics: Animals; Behavior, Animal; Chloroquine; Cyclopropanes; Disease Models, Animal; Histamine; Hypodermoclysis; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Nitriles; Pruritus; Pyridones; Quinoxalines; Receptors, AMPA	2020
Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway. Nature communications, 2020, 12-11, Volume: 11, Issue:1 Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Pancreatic Ductal; Cell Death; Cell Transformation, Neoplastic; Diet; Disease Models, Animal; DNA; Female; Ferroptosis; Humans; Iron; Macrophages; Male; Membrane Proteins; Mice; Mice, Knockout; Pancreas; Pancreatitis; Phospholipid Hydroperoxide Glutathione Peroxidase; Proto-Oncogene Proteins p21(ras); Quinoxalines; Spiro Compounds; Tumor Microenvironment	2020
New Dibenzoquinoxalines Inhibit Triple-Negative Breast Cancer Growth by Dual Targeting of Topoisomerase 1 and the Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; DNA Damage; DNA Topoisomerases, Type I; Down-Regulation; Drug Design; Female; G-Quadruplexes; Humans; Ligands; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-myc; Quinoxalines; Transplantation, Heterologous; Triple Negative Breast Neoplasms	2021
A quinoxaline-based compound ameliorates bone loss in ovariectomized mice. Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:23 Topics: Animals; Bone Density; Bone Resorption; Disease Models, Animal; Female; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Menopause; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteoporosis; Quinoxalines	2021
Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy. International journal of molecular sciences, 2021, Aug-13, Volume: 22, Issue:16 Topics: Animals; Computational Biology; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Glycolysis; Heart Ventricles; Male; Mice; Mitochondria, Heart; Oxidative Phosphorylation; Protein Interaction Maps; Proteomics; Quinoxalines; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Remodeling	2021
Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury. Cerebral cortex (New York, N.Y. : 1991), 2018, 05-01, Volume: 28, Issue:5 Topics: Action Potentials; Animals; Brain Injuries, Traumatic; Diffuse Axonal Injury; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neocortex; Nerve Tissue Proteins; Neural Inhibition; Neural Pathways; Parvalbumins; Quinoxalines; Valine; Vesicular Inhibitory Amino Acid Transport Proteins	2018
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor. Molecular cancer therapeutics, 2017, Volume: 16, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Humans; Lysosomes; Male; Mice; Molecular Targeted Therapy; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptors, Fibroblast Growth Factor; Signal Transduction; Xenograft Model Antitumor Assays	2017
Deconstructing behavioral neuropharmacology with cellular specificity. Science (New York, N.Y.), 2017, 04-07, Volume: 356, Issue:6333 Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Drug Design; Excitatory Amino Acid Antagonists; Long-Term Potentiation; Mice; Muscarinic Antagonists; Neurons; Optogenetics; Parkinson Disease; Quinoxalines; Receptors, Glutamate	2017
Downregulation of PI3K-γ in a mouse model of sepsis-induced myocardial dysfunction. Cytokine, 2017, Volume: 96 Topics: Animals; Cardiomyopathies; Chromones; Class II Phosphatidylinositol 3-Kinases; Cytokines; Disease Models, Animal; Down-Regulation; Interleukin-6; Lipopolysaccharides; Mice; Morpholines; Myocardium; Quinoxalines; Sepsis; Signal Transduction; Thiazolidinediones; Tumor Necrosis Factor-alpha	2017
In vitro and in vivo assessment of newer quinoxaline-oxadiazole hybrids as antimicrobial and antiprotozoal agents. International journal of antimicrobial agents, 2017, Volume: 50, Issue:3 Topics: Animals; Anti-Infective Agents; Bacteria; Chagas Disease; Disease Models, Animal; Fungi; Male; Mice; Molecular Structure; Oxadiazoles; Quinoxalines; Trypanosoma cruzi	2017
Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain. Journal of neuroscience research, 2018, Volume: 96, Issue:2 Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalidomide; Valine	2018
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma. BMC neuroscience, 2017, 08-14, Volume: 18, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Disease Models, Animal; Female; Imidazoles; Macrophages; Microglia; Nerve Degeneration; Nystagmus, Optokinetic; Optic Nerve Injuries; Oxidative Stress; Piperazines; Purinergic P2X Receptor Antagonists; Quinoxalines; Random Allocation; Ranvier's Nodes; Rats; Receptors, AMPA; Receptors, Purinergic P2X7	2017
A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy. Scientific reports, 2017, 09-22, Volume: 7, Issue:1 Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Kainic Acid; Male; Mice; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors; Treatment Outcome	2017
Soluble guanylyl cyclase is a critical regulator of migraine-associated pain. Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:8 Topics: Adrenergic beta-Antagonists; Allosteric Regulation; Animals; Anticonvulsants; Calcitonin Gene-Related Peptide; Disease Models, Animal; Enzyme Inhibitors; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Migraine Disorders; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxadiazoles; Propranolol; Proto-Oncogene Proteins c-fos; Quinoxalines; Serotonin 5-HT1 Receptor Agonists; Soluble Guanylyl Cyclase; Sumatriptan; Topiramate	2018
Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth. Circulation, 2018, 08-14, Volume: 138, Issue:7 Topics: Animals; Antibiotics, Antineoplastic; Autophagy; Autophagy-Related Proteins; Breast Neoplasms; Cardiotoxicity; Class Ib Phosphatidylinositol 3-Kinase; Cytoprotection; Disease Models, Animal; Doxorubicin; Female; Genes, erbB-2; Heart Diseases; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Myocytes, Cardiac; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinoxalines; Thiazolidinediones; Toll-Like Receptor 9; Tumor Burden	2018
Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes. Brain : a journal of neurology, 2018, 06-01, Volume: 141, Issue:6 Topics: Age Factors; Animals; Benzamides; Corpus Striatum; Cyclic AMP; Disease Models, Animal; Drosophila; Drosophila Proteins; Exploratory Behavior; Gait; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Induced Pluripotent Stem Cells; Mice; Mice, Transgenic; Mutation; Neurons; Phenotype; Quinoxalines; Receptors, G-Protein-Coupled; Thiophenes; Walking	2018
Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nature communications, 2018, 04-17, Volume: 9, Issue:1 Topics: Adult; Animals; Biopsy; Cell Line; Chagas Cardiomyopathy; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Female; Heart; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myeloid Cells; Myocardium; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Signal Transduction; Thiazolidinediones; Trypanosoma cruzi; Up-Regulation	2018
Kcnj6(GIRK2) trisomy is not sufficient for conferring the susceptibility to infantile spasms seen in the Ts65Dn mouse model of down syndrome. Epilepsy research, 2018, Volume: 145 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Down Syndrome; Electroencephalography; Embryo, Mammalian; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genotype; Hippocampus; Humans; In Vitro Techniques; Infant; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Peptide Hydrolases; Quinoxalines; Sodium Oxybate; Spasms, Infantile; Trisomy	2018
A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Scientific reports, 2018, Jul-20, Volume: 8, Issue:1 Topics: Angiotensin II; Animals; Cell Proliferation; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Kidney; Mice; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinoxalines; Renal Insufficiency, Chronic; Thiazolidinediones	2018
Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nature neuroscience, 2018, Volume: 21, Issue:10 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cells, Cultured; Cerebral Cortex; Cuprizone; Disease Models, Animal; Egtazic Acid; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Freund's Adjuvant; Hyperkinesis; Membrane Potentials; Mice; Mice, Transgenic; Microglia; Myelin Proteolipid Protein; Peptide Fragments; Proto-Oncogene Proteins c-fos; Quinoxalines; Recovery of Function; Sodium Channel Blockers; Tetrodotoxin	2018
Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection. Experimental brain research, 2019, Volume: 237, Issue:1 Topics: Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Ectodysplasins; Female; Imidazoles; Ion Channels; Macrophages; Microfilament Proteins; Microglia; Nerve Degeneration; Nystagmus, Optokinetic; Oligodendrocyte Transcription Factor 2; Optic Nerve Injuries; Piperazines; Quinoxalines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Rosaniline Dyes; Tubulin	2019
Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis. Scientific reports, 2018, 11-07, Volume: 8, Issue:1 Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Biopsy; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Enzyme Inhibitors; Imidazoles; Immunohistochemistry; Injections, Intra-Articular; Mice; NF-kappa B; Osteoarthritis, Knee; Quinoxalines; Signal Transduction; Treatment Outcome	2018
Precision-cut lung slices from bleomycin treated animals as a model for testing potential therapies for idiopathic pulmonary fibrosis. Pulmonary pharmacology & therapeutics, 2019, Volume: 55 Topics: Animals; Bleomycin; Disease Models, Animal; Idiopathic Pulmonary Fibrosis; Imidazoles; Indoles; Lung; Male; Mice; Mice, Inbred C57BL; Quinoxalines	2019
Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids. Neoplasia (New York, N.Y.), 2019, Volume: 21, Issue:6 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Humans; Mice; Optical Imaging; Organoids; Quinoxalines; Single-Cell Analysis; Sulfonamides; Tumor Microenvironment	2019
Inhibition of PI3Kγ by AS605240 Protects tMCAO Mice by Attenuating Pro-Inflammatory Signaling and Cytokine Release in Reactive Astrocytes. Neuroscience, 2019, 09-01, Volume: 415 Topics: Animals; Astrocytes; Brain Ischemia; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Mice, Inbred C57BL; NF-kappaB-Inducing Kinase; Protective Agents; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Stroke; Thiazolidinediones	2019
Targeting cholecystokinin-2 receptor for pancreatic cancer chemoprevention. Molecular carcinogenesis, 2019, Volume: 58, Issue:10 Topics: Adenocarcinoma; Animals; Benzodiazepinones; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Chemoprevention; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Proteins; Pancreatic Neoplasms; Phenylurea Compounds; Proto-Oncogene Proteins p21(ras); Quinoxalines; Receptor, Cholecystokinin B; Signal Transduction; Sulfonamides	2019
(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism. The international journal of neuropsychopharmacology, 2019, 10-01, Volume: 22, Issue:10 Topics: Animals; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Ketamine; Lipopolysaccharides; Male; Mice; Microdialysis; Microinjections; Norepinephrine; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Serotonin; Stereoisomerism	2019
Heteromeric nicotinic receptors are involved in the sensitization and addictive properties of MDMA in mice. Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jul-01, Volume: 44 Topics: Analysis of Variance; Animals; Benzazepines; Brain; Cholinergic Agents; Conditioning, Operant; Dihydro-beta-Erythroidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hallucinogens; Hyperkinesis; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Protein Binding; Quinoxalines; Radionuclide Imaging; Receptors, Nicotinic; Substance-Related Disorders; Tritium; Varenicline	2013
Ex vivo micro-computed tomography analysis of bleomycin-induced lung fibrosis for preclinical drug evaluation. The European respiratory journal, 2013, Volume: 42, Issue:6 Topics: Animals; Bleomycin; Chromatography, High Pressure Liquid; Collagen; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Fibrosis; Humans; Imidazoles; Lung; Male; Mice; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Treatment Outcome; X-Ray Microtomography	2013
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β. Nature neuroscience, 2013, Volume: 16, Issue:5 Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Channelrhodopsins; Corpus Striatum; Corticosterone; Disease Models, Animal; DNA Breaks, Double-Stranded; Excitatory Amino Acid Antagonists; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Histones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Photic Stimulation; Quinoxalines; Reactive Oxygen Species; Stress, Physiological; tau Proteins; Valine	2013
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease. PloS one, 2013, Volume: 8, Issue:4 Topics: Airway Remodeling; Animals; Antibiotics, Antineoplastic; Bleomycin; Cluster Analysis; Disease Models, Animal; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Humans; Idiopathic Pulmonary Fibrosis; Imidazoles; Inflammation; Lung; Male; Mice; Mitosis; Protein Serine-Threonine Kinases; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction	2013
EPAC inhibition of SUR1 receptor increases glutamate release and seizure vulnerability. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-15, Volume: 33, Issue:20 Topics: Animals; Bicuculline; Biophysics; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; Guanine Nucleotide Exchange Factors; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Kainic Acid; KATP Channels; Male; Membrane Potentials; Mice; Mice, Knockout; Patch-Clamp Techniques; Probability; Protein Binding; Quinoxalines; Synaptosomes; Transduction, Genetic	2013
Brimonidine protects against loss of Thy-1 promoter activation following optic nerve crush. BMC ophthalmology, 2013, Jun-27, Volume: 13, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Analysis of Variance; Animals; Brimonidine Tartrate; Cell Count; Disease Models, Animal; Female; Longitudinal Studies; Male; Mice; Microscopy, Fluorescence; Nerve Crush; Optic Nerve Injuries; Promoter Regions, Genetic; Protective Agents; Quinoxalines; Retinal Ganglion Cells; Thy-1 Antigens	2013
Anxiolytic-like effect of N-n-butyl-3-methoxyquinoxaline-2-carboxamide (60) in experimental mouse models of anxiety. Indian journal of experimental biology, 2013, Volume: 51, Issue:7 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Molecular Structure; Quinoxalines; Receptors, Serotonin, 5-HT3	2013
Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. Neuropharmacology, 2013, Volume: 75 Topics: Animals; Anxiety; Apomorphine; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA-A Receptor Antagonists; Male; Maze Learning; Nitric Oxide Synthase; Oxadiazoles; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1	2013
CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors. PloS one, 2013, Volume: 8, Issue:8 Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzofurans; Binding Sites; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Models, Molecular; Phosphorylation; Prostatic Neoplasms; Protein Binding; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Quinoxalines; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Xenograft Model Antitumor Assays	2013
Synthesis, radiofluorination, and in vivo evaluation of novel fluorinated and iodinated radiotracers for PET imaging and targeted radionuclide therapy of melanoma. Journal of medicinal chemistry, 2013, Nov-14, Volume: 56, Issue:21 Topics: Animals; Disease Models, Animal; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Structure; Positron-Emission Tomography; Quinoxalines; Radioactive Tracers; Tissue Distribution; Tumor Cells, Cultured	2013
Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis. PloS one, 2013, Volume: 8, Issue:9 Topics: Animals; Biomarkers; Cell Proliferation; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hypoxia; Neurogenesis; Neurons; Oligodendroglia; Organ Specificity; Quinoxalines; Rats; Seizures; Time Factors; TOR Serine-Threonine Kinases; Wnt Signaling Pathway	2013
AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures. Epilepsia, 2013, Volume: 54, Issue:11 Topics: Aging; Animals; Animals, Newborn; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Hippocampus; Male; Neurons; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Seizures	2013
MicroRNA-214 antagonism protects against renal fibrosis. Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:1 Topics: Animals; Disease Models, Animal; Fibrosis; Gene Deletion; Gene Expression; Humans; Imidazoles; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Quinoxalines; Renal Insufficiency, Chronic; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Ureteral Obstruction	2014
Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage. Annals of neurology, 2014, Volume: 75, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Calcium; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Glycogen; Hydrogen-Ion Concentration; Hypoglycemia; Kynurenic Acid; Lactic Acid; Leukoencephalopathies; Mice; Mice, Inbred C57BL; Optic Nerve Injuries; Quinoxalines; Receptors, N-Methyl-D-Aspartate	2014
Differential regulation of peripheral IL-1β-induced mechanical allodynia and thermal hyperalgesia in rats. Pain, 2014, Volume: 155, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Interleukin-1beta; Male; Nerve Tissue Proteins; Pain Threshold; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion	2014
Orally active antischistosomal early leads identified from the open access malaria box. PLoS neglected tropical diseases, 2014, Volume: 8, Issue:1 Topics: Administration, Oral; Animals; Anthelmintics; Disease Models, Animal; Female; Inhibitory Concentration 50; Mice; Parasite Load; Parasitic Sensitivity Tests; Quinoxalines; Schistosoma mansoni; Schistosomiasis mansoni; Urea	2014
Postsynaptic FMRP promotes the pruning of cell-to-cell connections among pyramidal neurons in the L5A neocortical network. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Feb-26, Volume: 34, Issue:9 Topics: Animals; Animals, Newborn; Cell Communication; Disease Models, Animal; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycine; Glycine Agents; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Transgenic; Neocortex; Nerve Net; Pyramidal Cells; Quinoxalines; Synapses	2014
Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway. Molecular cancer therapeutics, 2014, Volume: 13, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Humans; Inhibitory Concentration 50; Mice; Neoplasms; Neovascularization, Pathologic; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinoxalines; Ribosomal Protein S6 Kinases; Signal Transduction; Sulfonamides; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays	2014
Effect of (4a) a novel 5-HT3 receptor antagonist on chronic unpredictable mild stress induced depressive-like behavior in mice: an approach using behavioral tests battery. Journal of basic and clinical physiology and pharmacology, 2015, Volume: 26, Issue:1 Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Mice; Piperazines; Quinoxalines; Serotonin 5-HT3 Receptor Antagonists; Stress, Psychological; Sucrose	2015
Vasoconstriction and anti-inflammatory properties of the selective α-adrenergic receptor agonist brimonidine. Journal of dermatological science, 2014, Volume: 75, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Anti-Inflammatory Agents; Biopsy; Brimonidine Tartrate; Disease Models, Animal; Female; Humans; Inflammation; Mice, Inbred BALB C; Quinoxalines; Receptors, Adrenergic, alpha-2; Skin; Tissue Culture Techniques; Vasoconstrictor Agents; Vasodilation	2014
The role of GluN2A and GluN2B subunits on the effects of NMDA receptor antagonists in modeling schizophrenia and treating refractory depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:11 Topics: Animals; Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Phenols; Piperidines; Prefrontal Cortex; Quinoxalines; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin; Stereotyped Behavior	2014
Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats. Behavioural brain research, 2014, Sep-01, Volume: 271 Topics: Adaptation, Psychological; Amino Acids; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Ketamine; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stress, Psychological; Swimming; Time Factors; Xanthenes	2014
Recovery of vascular function after exposure to a single bout of segmental vibration. Journal of toxicology and environmental health. Part A, 2014, Volume: 77, Issue:17 Topics: Acetylcholine; Animals; Arteries; Brimonidine Tartrate; Disease Models, Animal; Endothelium, Vascular; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Vibration	2014
Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia. Experimental neurology, 2014, Volume: 261 Topics: Animals; Animals, Newborn; Carrier Proteins; Corpus Striatum; Cricetinae; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Dystonin; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Magnesium; Male; Mutation; Nerve Tissue Proteins; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors; Valine	2014
Neuropharmacological effect of novel 5-HT3 receptor antagonist, N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n) on chronic unpredictable mild stress-induced molecular and cellular response: Behavioural and biochemical evidences. Pharmacological reports : PR, 2014, Volume: 66, Issue:5 Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Catalase; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Glutathione; Lipid Peroxidation; Male; Mice; Motor Activity; Quinoxalines; Serotonin 5-HT3 Receptor Antagonists; Superoxide Dismutase; Swimming	2014
Antidepressant-like effects of a novel 5-HT3 receptor antagonist 6z in acute and chronic murine models of depression. Acta pharmacologica Sinica, 2014, Volume: 35, Issue:12 Topics: Acute Disease; Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Benzothiazoles; Biomarkers; Brain; Chronic Disease; Corticosterone; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Feeding Behavior; Female; Fluoxetine; Guinea Pigs; Hypothalamo-Hypophyseal System; Ileum; Lipid Peroxidation; Male; Mice; Motor Activity; Oxidative Stress; Pituitary-Adrenal System; Quinoxalines; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists	2014
Varenicline aggravates plaque formation through α7 nicotinic acetylcholine receptors in ApoE KO mice. Biochemical and biophysical research communications, 2014, Dec-12, Volume: 455, Issue:3-4 Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apolipoproteins E; Benzazepines; Body Weight; Cardiovascular Diseases; Cholesterol; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Agonists; Plaque, Atherosclerotic; Quinoxalines; Varenicline	2014
A novel in vivo model of focal light emitting diode-induced cone-photoreceptor phototoxicity: neuroprotection afforded by brimonidine, BDNF, PEDF or bFGF. PloS one, 2014, Volume: 9, Issue:12 Topics: Animals; Brain-Derived Neurotrophic Factor; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Electronics; Eye Proteins; Female; Fibroblast Growth Factor 2; Light; Nerve Growth Factors; Neuroprotective Agents; Quinoxalines; Rats, Sprague-Dawley; Retinal Cone Photoreceptor Cells; Serpins; Time Factors; Tomography, Optical Coherence	2014
Traumatic brain injury induces rapid enhancement of cortical excitability in juvenile rats. CNS neuroscience & therapeutics, 2015, Volume: 21, Issue:2 Topics: Animals; Animals, Newborn; Biophysics; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine	2015
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs. European journal of pharmacology, 2015, Feb-15, Volume: 749 Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol	2015
The effects of varenicline on sensory gating and exploratory behavior with pretreatment with nicotinic or 5-HT3A receptor antagonists. Behavioural pharmacology, 2015, Volume: 26, Issue:1-2 Topics: Animals; Benzazepines; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Nicotinic Agonists; Quinoxalines; Receptors, Serotonin, 5-HT3; Reflex, Startle; Schizophrenia; Sensory Gating; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Varenicline	2015
Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:7 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Dexamethasone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Humans; Memory Disorders; Memory, Episodic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mutation; Neuronal Plasticity; Quinoxalines; Receptors, Glucocorticoid; Recognition, Psychology; Valine	2015
The Selective PI3K Inhibitor XL147 (SAR245408) Inhibits Tumor Growth and Survival and Potentiates the Activity of Chemotherapeutic Agents in Preclinical Tumor Models. Molecular cancer therapeutics, 2015, Volume: 14, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinoxalines; Ribosomal Protein S6 Kinases; Signal Transduction; Sulfonamides; Xenograft Model Antitumor Assays	2015
Synchronous inhibitory potentials precede seizure-like events in acute models of focal limbic seizures. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Feb-18, Volume: 35, Issue:7 Topics: 4-Aminopyridine; Action Potentials; Animals; Bicuculline; Computer Simulation; Convulsants; Disease Models, Animal; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Guinea Pigs; In Vitro Techniques; Models, Biological; Neural Inhibition; Potassium Channel Blockers; Quinoxalines; Seizures	2015
PI3Kγ deficiency enhances seizures severity and associated outcomes in a mouse model of convulsions induced by intrahippocampal injection of pilocarpine. Experimental neurology, 2015, Volume: 267 Topics: Animals; Calcium; Calcium-Binding Proteins; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Doublecortin Domain Proteins; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Microtubule-Associated Proteins; Muscarinic Agonists; Neuropeptides; Pilocarpine; Prefrontal Cortex; Quinoxalines; Reaction Time; Seizures; Synaptosomes; Thiazolidinediones; Time Factors	2015
Seizure-related regulation of GABAA receptors in spontaneously epileptic rats. Neurobiology of disease, 2015, Volume: 77 Topics: Animals; Biotinylation; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Muscarinic Agonists; Neurons; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Valine	2015
Phosphatidylinositol 3-Kinase γ is required for the development of experimental cerebral malaria. PloS one, 2015, Volume: 10, Issue:3 Topics: Animals; Brain; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Extracellular Matrix; Female; Humans; Lung; Malaria, Cerebral; Mice; Phosphoinositide-3 Kinase Inhibitors; Plasmodium berghei; Quinoxalines; Survival Analysis; Thiazolidinediones	2015
The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy. Neuropharmacology, 2015, Volume: 95 Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Mice; Nitriles; Phenytoin; Pyridones; Quinoxalines; Receptors, AMPA; Seizures; Status Epilepticus	2015
Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Apr-08, Volume: 35, Issue:14 Topics: 4-Aminopyridine; Acetazolamide; Animals; Benzeneacetamides; Calcium Channels, N-Type; Cerebral Cortex; Channelopathies; Cortical Synchronization; Disease Models, Animal; Enzyme Inhibitors; Female; Male; Mice; Mice, Transgenic; Mutation; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Potassium Channel Blockers; Pyridines; Quinoxalines; Vibrissae	2015
Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways. BMC cancer, 2015, Mar-21, Volume: 15 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytosol; Disease Models, Animal; Gene Expression; Gene Silencing; Humans; Liver Neoplasms; Male; Metabolic Networks and Pathways; Mice; Neoplasms; Quinoxalines; Thymidine; Thymidine Kinase; Thymidine Phosphorylase; Tumor Burden; Xenograft Model Antitumor Assays	2015
Anti-inflammatory treatment of traumatic brain injury with Rabeximod reduces cerebral antigen presentation in mice. Journal of neuroscience research, 2015, Volume: 93, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Antigen Presentation; Body Weight; Brain Injuries; Cerebral Cortex; Cyclophosphamide; Cytokines; Dendritic Cells; Disease Models, Animal; Gene Expression Regulation; Indoles; Male; Mice; Mice, Inbred C57BL; Quinoxalines; RNA, Messenger; Time Factors	2015
Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo. Molecular cancer, 2015, Jun-17, Volume: 14 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Knockdown Techniques; Glioblastoma; Humans; Indolizines; Mice; Mitogen-Activated Protein Kinase Kinases; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Quinoxalines; RNA, Small Interfering; Signal Transduction; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2015
Neuroprotective Effects of Human Serum Albumin Nanoparticles Loaded With Brimonidine on Retinal Ganglion Cells in Optic Nerve Crush Model. Investigative ophthalmology & visual science, 2015, Volume: 56, Issue:9 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Drug Carriers; Humans; Immunohistochemistry; Intravitreal Injections; Male; Nanoparticles; Nerve Crush; Optic Nerve; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Serum Albumin	2015
Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice. Neuron, 2015, Sep-02, Volume: 87, Issue:5 Topics: Adrenergic Agents; Animals; Bacterial Proteins; Channelrhodopsins; Corpus Striatum; Disease Models, Animal; Dopamine; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Oxidopamine; Parkinsonian Disorders; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinoxalines; Substantia Nigra	2015
Inflammatory Pain Promotes Increased Opioid Self-Administration: Role of Dysregulated Ventral Tegmental Area μ Opioid Receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Sep-02, Volume: 35, Issue:35 Topics: Action Potentials; Analgesics, Opioid; Animals; Conditioning, Operant; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glycine Agents; Heroin; Hyperalgesia; Inflammation; Inhibitory Postsynaptic Potentials; Male; Neurons; Pain; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Strychnine; Sucrose; Ventral Tegmental Area	2015
GRPR/PI3Kγ: Partners in Central Transmission of Itch. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Dec-09, Volume: 35, Issue:49 Topics: Action Potentials; Animals; Anticarcinogenic Agents; Bombesin; Capsaicin; Central Nervous System; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Spinal; Gastrin-Releasing Peptide; Indoles; Male; Mice; Neurons; p-Methoxy-N-methylphenethylamine; Pain Threshold; Peptide Fragments; Phosphatidylinositol 3-Kinase; Pruritus; Quinoxalines; Reaction Time; Receptors, Bombesin; Synaptic Transmission; Thiazolidinediones	2015
Interneurons spark seizure-like activity in the entorhinal cortex. Neurobiology of disease, 2016, Volume: 87 Topics: 4-Aminopyridine; Action Potentials; Animals; Disease Models, Animal; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Interneurons; Male; Piperazines; Quinoxalines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Tissue Culture Techniques	2016
A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing. Neuron, 2016, Mar-16, Volume: 89, Issue:6 Topics: Action Potentials; Animals; Cholecystokinin; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Inflammation; Neural Pathways; Neuralgia; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; Receptors, Oxytocin; Spinal Cord; Supraoptic Nucleus; Transduction, Genetic; Vasopressins; Vesicular Glutamate Transport Protein 2	2016
AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-16, Volume: 36, Issue:11 Topics: Animals; Animals, Newborn; Apoptosis; Brain; Calcium Signaling; Cerebral Ventricles; Cytokines; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Glycerol; Hemorrhage; Humans; Leukoencephalopathies; Male; Nervous System Diseases; Nitriles; Pregnancy; Pyridones; Quinoxalines; Rabbits; Receptors, AMPA; Recovery of Function	2016
Anti-inflammatory Effects of Novel Polysaccharide Sacran Extracted from Cyanobacterium Aphanothece sacrum in Various Inflammatory Animal Models. Biological & pharmaceutical bulletin, 2016, Jul-01, Volume: 39, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line; Cyanobacteria; Cyclooxygenase 2; Cytokines; Dextrans; Disease Models, Animal; Edema; Female; Humans; Kaolin; Male; Mice, Inbred BALB C; Polysaccharides; Quinoxalines; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate	2016
New 6-Aminoquinoxaline Derivatives with Neuroprotective Effect on Dopaminergic Neurons in Cellular and Animal Parkinson Disease Models. Journal of medicinal chemistry, 2016, 07-14, Volume: 59, Issue:13 Topics: Animals; Cells, Cultured; Disease Models, Animal; Dopaminergic Neurons; Female; Male; Mice, Inbred C57BL; Neuroprotective Agents; Parkinson Disease; Quinoxalines; Rats, Sprague-Dawley; Structure-Activity Relationship	2016
Effects of NMDA-Receptor Antagonist on the Expressions of Bcl-2 and Bax in the Subventricular Zone of Neonatal Rats with Hypoxia-Ischemia Brain Damage. Cell biochemistry and biophysics, 2015, Volume: 73, Issue:2 Topics: Animals; bcl-2-Associated X Protein; Disease Models, Animal; Dizocilpine Maleate; Hypoxia-Ischemia, Brain; Immunohistochemistry; Lateral Ventricles; Neuroprotective Agents; Phenols; Piperidines; Protein Subunits; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2015
AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets. PloS one, 2016, Volume: 11, Issue:11 Topics: Aggrecans; Animals; Anticonvulsants; Behavior, Animal; Chondroitin ABC Lyase; Disease Models, Animal; Down-Regulation; Epilepsy; Immunohistochemistry; Male; Neurocan; Pentylenetetrazole; Peripheral Nerves; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tenascin	2016
Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT Molecular brain, 2016, 12-08, Volume: 9, Issue:1 Topics: Alternative Splicing; Animals; Anorexia; Appetite; Arcuate Nucleus of Hypothalamus; Base Sequence; Disease Models, Animal; Feeding Behavior; Mice; Mutant Proteins; Neurons; Prader-Willi Syndrome; Pro-Opiomelanocortin; Proto-Oncogene Proteins c-fos; Pyrazines; Quinoxalines; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists	2016
Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. Oncotarget, 2017, Mar-21, Volume: 8, Issue:12 Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinoma, Squamous Cell; Chemokines, CXC; Chemoprevention; Disease Models, Animal; Gene Expression Profiling; Lung Neoplasms; Mice; Pioglitazone; Precancerous Conditions; Quinoxalines; Sulfonamides; Thiazolidinediones; Transcriptome	2017
PI3Kγ Deficient NOD-Mice Are Protected from Diabetes by Restoring the Balance of Regulatory to Effector-T-Cells. PloS one, 2017, Volume: 12, Issue:1 Topics: Animals; CD4-Positive T-Lymphocytes; Cell Proliferation; Cell Survival; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Pancreas; Peptides; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; T-Lymphocytes, Regulatory; Thiazolidinediones	2017
Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 03-01, Volume: 37, Issue:9 Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sciatica; Subcellular Fractions; Synaptic Transmission; Valine	2017
Antidepressant & anxiolytic activities of N-(pyridin-3-yl) quinoxalin-2-carboxamide: A novel serotonin type 3 receptor antagonist in behavioural animal models. The Indian journal of medical research, 2016, Volume: 144, Issue:4 Topics: Animals; Antidepressive Agents; Anxiety; Depression; Depressive Disorder; Disease Models, Animal; Feeding and Eating Disorders; Male; Mice; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Rats; Rats, Wistar; Receptors, Serotonin; Schizophrenia; Serotonin; Serotonin 5-HT3 Receptor Antagonists	2016
Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity. Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:10 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Signaling; Disease Models, Animal; Excitatory Amino Acid Agonists; Glaucoma; Male; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Rabbits; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Rolipram	2008
Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Animals; Antitubercular Agents; Cyclic N-Oxides; Disease Models, Animal; Drug Resistance, Bacterial; Female; Humans; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Quinoxalines; Specific Pathogen-Free Organisms; Spleen; Structure-Activity Relationship; Treatment Outcome; Tuberculosis, Pulmonary	2008
Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice. Behavioral neuroscience, 2008, Volume: 122, Issue:5 Topics: Animals; Behavior, Animal; Benzazepines; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Fear; Freezing Reaction, Cataleptic; Learning Disabilities; Male; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Quinoxalines; Tobacco Use Disorder; Varenicline	2008
Effect of brimonidine on retinal ganglion cell survival in an optic nerve crush model. American journal of ophthalmology, 2009, Volume: 147, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Count; Cell Survival; Disease Models, Animal; Injections, Intraperitoneal; Nerve Crush; Neuroprotective Agents; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells	2009
Development of a high-performance liquid chromatographic method for the determination of a new potent radioiodinated melanoma imaging and therapeutic agent. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Nov-15, Volume: 875, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Stability; Iodine Radioisotopes; Linear Models; Male; Melanoma, Experimental; Mice; Neoplasm Transplantation; Quinoxalines; Radionuclide Imaging; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2008
Effect of exogenous nitric oxide on murine immune response induced by Aggregatibacter actinomycetemcomitans lipopolysaccharide. Journal of periodontal research, 2009, Volume: 44, Issue:4 Topics: Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Animals; Antibodies, Bacterial; Benzoates; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Guanylate Cyclase; Imidazoles; Immunity, Cellular; Immunization; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lipopolysaccharides; Lysine; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Oxadiazoles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Skin Diseases, Bacterial; Spleen; Th1 Cells	2009
[Hixozide, a novel combined antituberculosis preparation]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2008, Volume: 53, Issue:5-6 Topics: Animals; Antitubercular Agents; Cells, Cultured; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Isoniazid; Mice; Microbial Sensitivity Tests; Mycobacterium fortuitum; Mycobacterium tuberculosis; Quinoxalines; Tuberculosis, Pulmonary	2008
Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3 Topics: Animals; Aorta, Thoracic; Blood Pressure; Cecum; Cyclic GMP; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Female; Guanylate Cyclase; Methylene Blue; Mortality; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Vasoconstriction	2009
Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrot The American journal of pathology, 2009, Volume: 174, Issue:2 Topics: Animals; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Cell Proliferation; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Image Processing, Computer-Assisted; Imidazoles; Immunohistochemistry; Monocrotaline; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pulmonary Artery; Quinoxalines; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Smad3 Protein; Transforming Growth Factor beta1	2009
Abnormal network activity in a targeted genetic model of human double cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-14, Volume: 29, Issue:2 Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine	2009
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase. Neuroscience, 2009, Mar-17, Volume: 159, Issue:2 Topics: Animals; Convulsants; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Quinoxalines; Seizures	2009
Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect. European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3 Topics: Animals; Antidepressive Agents; Benzazepines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nicotinic Agonists; Quinoxalines; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Sertraline; Swimming; Varenicline	2009
Effects of chronic hypoxia on soluble guanylate cyclase activity in fetal and adult ovine cerebral arteries. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:1 Topics: Altitude Sickness; Animals; Cerebral Arteries; Chronic Disease; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Female; Fetus; Guanylate Cyclase; Hypoxia; Muscle, Smooth, Vascular; Nitric Oxide; Oxadiazoles; Pregnancy; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sheep; Soluble Guanylyl Cyclase; Vasodilation	2009
IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease. The journal of sexual medicine, 2009, Volume: 6, Issue:5 Topics: Animals; Disease Models, Animal; Fibrosis; Humans; Imidazoles; Male; Penile Induration; Penis; Protein Kinase Inhibitors; Quinoxalines; Rats	2009
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis. Annals of neurology, 2009, Volume: 66, Issue:1 Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amlodipine; Amyloid beta-Protein Precursor; Animals; Autoimmune Diseases; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cytokines; Disease Models, Animal; Drug Interactions; Ectodysplasins; Egtazic Acid; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Magnetic Resonance Imaging; Manganese; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neoplasm Proteins; omega-Conotoxin GVIA; Optic Nerve; Optic Neuritis; Quinoxalines; Rats; RNA-Binding Proteins	2009
Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Cell Line; Cystic Fibrosis Transmembrane Conductance Regulator; Cysts; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Membrane Potentials; Mice; Polycystic Kidney Diseases; Quinoxalines; Rats; Structure-Activity Relationship	2009
Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy. Clinical & experimental ophthalmology, 2009, Volume: 37, Issue:7 Topics: Animals; Brimonidine Tartrate; Disease Models, Animal; Eye Proteins; Fluorescent Antibody Technique, Indirect; Gene Expression; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Heme Oxygenase-1; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Neuroprotective Agents; Nitric Oxide Synthase Type III; Optic Neuropathy, Ischemic; Oxidative Stress; Quinoxalines; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Retinal Ganglion Cells; Retinal Neovascularization; Serpins; Superoxide Dismutase; Superoxide Dismutase-1; Vascular Endothelial Growth Factor A	2009
Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung. The European respiratory journal, 2010, Volume: 35, Issue:5 Topics: Acute Lung Injury; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Cell Movement; Chimera; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Flow Cytometry; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Lipopolysaccharides; Lung; Male; Membrane Proteins; Mice; Neutrophils; Phosphatidylinositol 3-Kinases; Quinoxalines; Thiazolidinediones	2010
Inhibition of phosphoinositide 3-kinase ameliorates dextran sodium sulfate-induced colitis in mice. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:1 Topics: Acute Disease; Animals; Blotting, Western; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chronic Disease; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Organ Size; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Severity of Illness Index; Spleen; Thiazolidinediones	2010
Roles of perirhinal and posterior piriform cortices in control and generation of seizures: a microinfusion study in rats exposed to soman. Neurotoxicology, 2010, Volume: 31, Issue:1 Topics: Animals; Anticonvulsants; Cerebral Cortex; Disease Models, Animal; Electroencephalography; GABA Agonists; Male; Muscarinic Antagonists; Muscimol; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Scopolamine; Seizures; Soman; Statistics, Nonparametric	2010
Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Dec-02, Volume: 29, Issue:48 Topics: Action Potentials; Age Factors; Amyotrophic Lateral Sclerosis; Animals; Biophysics; Chi-Square Distribution; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Interneurons; Mice; Mice, Transgenic; Motor Neurons; Mutation; N-Methylaspartate; Patch-Clamp Techniques; Psychomotor Performance; Quinoxalines; Reaction Time; Reflex; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Synapses	2009
Retinal oxidative stress induced by intraocular hypertension in rats may be ameliorated by brimonidine treatment and N-acetyl cysteine supplementation. Journal of glaucoma, 2009, Volume: 18, Issue:9 Topics: Acetylcysteine; Animals; Brimonidine Tartrate; Catalase; Disease Models, Animal; Drug Therapy, Combination; Glutathione Peroxidase; Hyaluronic Acid; Intraocular Pressure; Male; Malondialdehyde; Nitric Oxide; Ocular Hypertension; Oxidative Stress; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Diseases; Tonometry, Ocular	2009
Involvement of phosphoinositide 3-kinase gamma in angiogenesis and healing of experimental myocardial infarction in mice. Circulation research, 2010, Mar-05, Volume: 106, Issue:4 Topics: Animals; Apoptosis; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inflammation; Leukocytes; Male; Mice; Morpholines; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinoxalines; Recovery of Function; Regeneration; RNA Interference; Signal Transduction; Thiazolidinediones; Time Factors; Transfection; Ventricular Function, Left	2010
Reaction of Müller cells in an experimental rat model of increased intraocular pressure following timolol, latanoprost and brimonidine. Brain research bulletin, 2010, Apr-29, Volume: 82, Issue:1-2 Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Disease Models, Animal; Glaucoma; Glial Fibrillary Acidic Protein; Gliosis; Intraocular Pressure; Latanoprost; Male; Neuroglia; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Retina; Timolol; Tonometry, Ocular	2010
Effects of pharmacological entopeduncular manipulations on idiopathic dystonia in the dt(sz) mutant hamster. Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:6 Topics: Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dystonia; Entopeduncular Nucleus; Excitatory Amino Acid Antagonists; GABA Agents; Microinjections; Muscimol; Nipecotic Acids; Oximes; Pentylenetetrazole; Quinoxalines; Reaction Time; Severity of Illness Index; Time Factors; Valine	2010
Concomitant administration of nitric oxide and glucocorticoids improves protection against bronchoconstriction in a murine model of asthma. Journal of applied physiology (Bethesda, Md. : 1985), 2010, Volume: 109, Issue:2 Topics: Administration, Inhalation; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Cyclic GMP; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Glucocorticoids; Guanylate Cyclase; Hydrazines; Hydrocortisone; Injections, Intraperitoneal; Lipopolysaccharides; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Ovalbumin; Oxadiazoles; Pneumonia; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Respiration, Artificial; Respiratory Mechanics; Soluble Guanylyl Cyclase	2010
Alpha2-adrenergic receptors and their core involvement in the process of axonal growth in retinal explants. Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:12 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Autoradiography; Axons; Brimonidine Tartrate; Clonidine; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique, Indirect; Glaucoma; Glial Fibrillary Acidic Protein; Optic Nerve Injuries; Organ Culture Techniques; Platelet Activating Factor; Protein Disulfide-Isomerases; Proteomics; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Laminin; Retina; Retinal Degeneration; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2010
Effects of PI3Kgamma inhibition using AS-605240 in acute myocardial infarction. Circulation research, 2010, Jul-23, Volume: 107, Issue:2 Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Genotype; Mice; Mice, Knockout; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinoxalines; Thiazolidinediones; Ventricular Function, Left; Ventricular Remodeling	2010
Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jul-28, Volume: 30, Issue:30 Topics: Alanine; Alcohol Drinking; Analysis of Variance; Animals; Benzazepines; Central Nervous System Depressants; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drinking Behavior; Drug Combinations; Ethanol; Gene Expression Regulation; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Quinoxalines; Receptors, Nicotinic; Tyrosine 3-Monooxygenase; Varenicline; Ventral Tegmental Area	2010
The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array. Neuropharmacology, 2011, Volume: 60, Issue:7-8 Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; CA3 Region, Hippocampal; Disease Models, Animal; Electrodes; Epilepsy; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Mice; Mice, Inbred C57BL; Microarray Analysis; Motion Pictures; Piperazines; Potassium Channel Blockers; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Software; Somatosensory Cortex	2011
Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats. Neuropharmacology, 2011, Volume: 60, Issue:6 Topics: Animals; Antiparkinson Agents; Azetidines; Benzazepines; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Levodopa; Male; Nicotinic Agonists; Oxidopamine; Parkinson Disease; Quinoxalines; Rats; Rats, Sprague-Dawley; Varenicline	2011
Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:5 Topics: Abnormalities, Drug-Induced; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Animals, Newborn; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Epididymis; Female; Fetal Development; Male; Maternal Exposure; No-Observed-Adverse-Effect Level; Organ Size; Pregnancy; Quinoxalines; Rats; Rats, Wistar; Reproduction; Teratogens; Testis	2011
Network oscillations in rod-degenerated mouse retinas. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-09, Volume: 31, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Age Factors; Animals; Carbenoxolone; Cyclooxygenase Inhibitors; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Glycine; In Vitro Techniques; Light; Male; Meclofenamic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Neurologic Mutants; Nerve Net; Neural Inhibition; Periodicity; Pyridazines; Quinoxalines; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Sodium Channel Blockers; Statistics as Topic; Tetrodotoxin	2011
Kainate administered to adult zebrafish causes seizures similar to those in rodent models. The European journal of neuroscience, 2011, Volume: 33, Issue:7 Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Quinoxalines; Rats; Receptors, Glutamate; Seizures; Zebrafish	2011
Inner and outer retinal mechanisms engaged by epiretinal stimulation in normal and rd mice. Visual neuroscience, 2011, Volume: 28, Issue:2 Topics: Animals; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glycine Agents; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Confocal; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Retina; Retinal Degeneration; Retinal Ganglion Cells; Sesterterpenes; Strychnine; Visual Pathways	2011
Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats. Investigative ophthalmology & visual science, 2011, Jul-20, Volume: 52, Issue:8 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Choroidal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Fluorescein Angiography; Humans; Immunoblotting; Infant, Newborn; Intravitreal Injections; Laser Coagulation; Male; Mice; Mice, Inbred C57BL; Oxygen; Quinoxalines; Rabbits; Rats; Rats, Inbred BN; Retinal Neovascularization; Retinopathy of Prematurity; Time Factors	2011
An immunohistochemical analysis of the neuroprotective effects of memantine, hyperbaric oxygen therapy, and brimonidine after acute ischemia reperfusion injury. Molecular vision, 2011, Apr-26, Volume: 17 Topics: Animals; Brimonidine Tartrate; Cell Count; Disease Models, Animal; Hyperbaric Oxygenation; Immunohistochemistry; Injections, Intravenous; Memantine; Neuroprotective Agents; Ophthalmic Solutions; Quinoxalines; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Ganglion Cells	2011
Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats. Neurotoxicology, 2011, Volume: 32, Issue:6 Topics: Animals; Anticonvulsants; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Lethal Dose 50; Levetiracetam; Male; Motor Activity; Muscimol; Nicotinic Antagonists; Piracetam; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors	2011
Prevention of retinal ganglion cell swelling by systemic brimonidine in a rat experimental glaucoma model. Clinical & experimental ophthalmology, 2011, Volume: 39, Issue:8 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glaucoma, Open-Angle; Injections, Intraperitoneal; Intraocular Pressure; Papilledema; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Treatment Outcome	2011
Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression. Behavioural brain research, 2011, Oct-10, Volume: 224, Issue:1 Topics: Analysis of Variance; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Helplessness, Learned; Hindlimb Suspension; Ketamine; Male; Mice; Mice, Inbred ICR; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors	2011
Behavioral and in vivo electrophysiological evidence for presymptomatic alteration of prefrontostriatal processing in the transgenic rat model for huntington disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jun-15, Volume: 31, Issue:24 Topics: Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; Animals, Genetically Modified; Behavior, Animal; Corpus Striatum; Discrimination, Psychological; Disease Models, Animal; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Antagonists; Genotype; Huntingtin Protein; Huntington Disease; Inhibition, Psychological; Longitudinal Studies; Male; Nerve Tissue Proteins; Neural Pathways; Neuropsychological Tests; Nuclear Proteins; Picrotoxin; Prefrontal Cortex; Psychomotor Performance; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex, Startle; Synaptic Membranes; Trinucleotide Repeat Expansion	2011
[Edema in nervous tissue studied on model of hemorrhagic stroke in vitro]. Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Edema; Disease Models, Animal; Excitatory Amino Acid Antagonists; In Vitro Techniques; Intracranial Hemorrhage, Hypertensive; Nerve Tissue; Olfactory Pathways; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, Ionotropic Glutamate; Stroke; Synaptic Potentials; Time Factors	2011
Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain. Bioorganic & medicinal chemistry letters, 2011, Jul-15, Volume: 21, Issue:14 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Brain; Disease Models, Animal; Humans; Iodine Radioisotopes; Mice; Mice, Transgenic; Peptide Fragments; Plaque, Amyloid; Protein Binding; Quinoxalines; Radiography; Radiopharmaceuticals; Tissue Distribution	2011
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test. Behavioural brain research, 2011, Nov-20, Volume: 225, Issue:1 Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones	2011
Axon-glia synapses are highly vulnerable to white matter injury in the developing brain. Journal of neuroscience research, 2012, Volume: 90, Issue:1 Topics: Animals; Animals, Newborn; Antigens; Brain Injuries; Carotid Artery Diseases; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; Glial Fibrillary Acidic Protein; Hypoxia-Ischemia, Brain; Leukoencephalopathies; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Minocycline; Myelin Basic Protein; Nerve Fibers, Myelinated; Neuroglia; Polysaccharides; Proteoglycans; Quinoxalines; Receptors, AMPA; Synapses; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2	2012
Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:5 Topics: Animals; Benzoates; Cells, Cultured; Cyclic GMP; Disease Models, Animal; Female; Fetus; Guanylate Cyclase; Humans; Hydrogen Peroxide; Infant, Newborn; Isoenzymes; Myocytes, Smooth Muscle; Nitric Oxide; Nitroprusside; Oxadiazoles; Persistent Fetal Circulation Syndrome; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Quinoxalines; Receptors, Cytoplasmic and Nuclear; Sheep; Soluble Guanylyl Cyclase; Vascular Resistance; Vasodilation; Vasodilator Agents	2011
Anti-depressant-like activity of a novel serotonin type-3 (5-HT3) receptor antagonist in rodent models of depression. Indian journal of experimental biology, 2011, Volume: 49, Issue:8 Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hindlimb Suspension; Male; Mice; Molecular Structure; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Swimming	2011
Brimonidine tartrate-eudragit long-acting nanoparticles: formulation, optimization, in vitro and in vivo evaluation. AAPS PharmSciTech, 2011, Volume: 12, Issue:4 Topics: Acrylic Resins; Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Glaucoma; Hydrogen-Ion Concentration; Intraocular Pressure; Kinetics; Nanoparticles; Nanotechnology; Quinoxalines; Rabbits; Solubility; Technology, Pharmaceutical	2011
Acute administration of AMPA/Kainate blocker combined with delayed transplantation of neural precursors improves lower urinary tract function in spinal injured rats. Brain research, 2011, Oct-18, Volume: 1418 Topics: Animals; Calcitonin Gene-Related Peptide; Diagnostic Imaging; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Flow Cytometry; Motor Activity; Neural Stem Cells; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Recovery of Function; Serotonin; Spinal Injuries; Urinary Bladder Diseases; Urination; Urodynamics	2011
Biodegradable ocular inserts for sustained delivery of brimonidine tartarate: preparation and in vitro/in vivo evaluation. AAPS PharmSciTech, 2011, Volume: 12, Issue:4 Topics: Absorbable Implants; Acrylic Resins; Administration, Ophthalmic; Adrenergic alpha-2 Receptor Agonists; Alginates; Animals; Brimonidine Tartrate; Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Compounding; Glaucoma; Glucuronic Acid; Hexuronic Acids; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Intraocular Pressure; Kinetics; Methylcellulose; Ophthalmic Solutions; Polymers; Polymethacrylic Acids; Polyvinyls; Povidone; Quinoxalines; Rabbits; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; X-Ray Diffraction	2011
The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain. Psychopharmacology, 2012, Volume: 221, Issue:1 Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Brimonidine Tartrate; Clonidine; Desipramine; Disease Models, Animal; Idazoxan; Locus Coeruleus; Male; MAP Kinase Signaling System; Medulla Oblongata; Neuralgia; Norepinephrine; Prefrontal Cortex; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Signal Transduction; Spinal Cord	2012
System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo. Experimental neurology, 2012, Volume: 233, Issue:1 Topics: Animals; Cystine; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Gene Expression Regulation; Glutamic Acid; Glutathione; Laser Capture Microdissection; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Microglia; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Quinoxalines; Spinal Cord Diseases	2012
Synaptic transmission changes in fear memory circuits underlie key features of an animal model of schizophrenia. Behavioural brain research, 2012, Feb-01, Volume: 227, Issue:1 Topics: Action Potentials; Amygdala; Animals; Area Under Curve; Biophysics; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; Glutamate Decarboxylase; Hippocampus; In Vitro Techniques; Male; Memory Disorders; Neurons; Parvalbumins; Patch-Clamp Techniques; Phencyclidine; Quinoxalines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Schizophrenia; Synaptic Transmission; Time Factors	2012
Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase. Journal of controlled release : official journal of the Controlled Release Society, 2012, Apr-10, Volume: 159, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain Ischemia; CA1 Region, Hippocampal; Diazepam; Disease Models, Animal; Drug Delivery Systems; Gerbillinae; Glutathione Transferase; Intramolecular Oxidoreductases; Lipocalins; Male; Mice; Pyramidal Cells; Quinoxalines; Recombinant Fusion Proteins; Solubility; Water	2012
Investigation of the antidyskinetic site of action of metabotropic and ionotropic glutamate receptor antagonists. Intracerebral infusions in 6-hydroxydopamine-lesioned rats with levodopa-induced dyskinesia. European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3 Topics: Animals; Anti-Dyskinesia Agents; Disease Models, Animal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Infusions, Intraventricular; Levodopa; Male; Oxidopamine; Phenols; Piperidines; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Subthalamic Nucleus; Thiazoles	2012
Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma. Investigative ophthalmology & visual science, 2012, Jun-20, Volume: 53, Issue:7 Topics: Animals; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Feasibility Studies; Intraocular Pressure; Latanoprost; Mice; Mice, Inbred C57BL; Microspheres; Muscarinic Agonists; Ocular Hypertension; Optic Nerve; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Retinal Ganglion Cells; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence	2012
Enhanced NMDA receptor-dependent thalamic excitation and network oscillations in stargazer mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-08, Volume: 32, Issue:32 Topics: Action Potentials; Animals; Biophysical Phenomena; Calcium Channels; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Glutamates; In Vitro Techniques; Indoles; Male; Mice; Mice, Mutant Strains; Nerve Net; Neurons; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synapses; Thalamic Nuclei; Time Factors; Valine; Vesicular Glutamate Transport Protein 1	2012
[MK-801 or DNQX reduces electroconvulsive shock-induced impairment of learning-memory and hyperphosphorylation of Tau in rats]. Sheng li xue bao : [Acta physiologica Sinica], 2012, Aug-25, Volume: 64, Issue:4 Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Electroshock; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Learning; Memory; Memory Disorders; Phosphorylation; Quinoxalines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; tau Proteins	2012
TNF-α triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury. Experimental neurology, 2012, Volume: 238, Issue:2 Topics: Age Factors; Animals; Calcium; Cobalt; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agents; Female; Isoquinolines; Kainic Acid; Motor Neurons; Neurofilament Proteins; Organ Culture Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha	2012
Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Sep-26, Volume: 32, Issue:39 Topics: Anesthetics, Local; Animals; Bacterial Proteins; Carrier Proteins; Channelrhodopsins; Disease Models, Animal; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Forelimb; Hyperalgesia; In Vitro Techniques; Ischemia; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Optogenetics; Physical Stimulation; Quinoxalines; Reperfusion Injury; Tetrodotoxin; Valine	2012
The activity of lowering intraocular pressure of cassiae seed extract in a DBA/2J mouse glaucoma model. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:1 Topics: Acetazolamide; Animals; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Cassia; Chromatography, High Pressure Liquid; Disease Models, Animal; Glaucoma; Glycosides; Intraocular Pressure; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred DBA; Plant Extracts; Polyphenols; Quinoxalines; Seeds	2013
Cannabinoid receptor subtypes 1 and 2 mediate long-lasting neuroprotection and improve motor behavior deficits after transient focal cerebral ischemia. Neuroscience, 2012, Dec-27, Volume: 227 Topics: Animals; Arachidonic Acids; Brain; Brain Infarction; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Ectodysplasins; Endocannabinoids; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Indans; Infarction, Middle Cerebral Artery; Leukocyte Common Antigens; Male; Movement Disorders; Neuroprotective Agents; Polyunsaturated Alkamides; Psychomotor Performance; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonic Acids; Time Factors	2012
Enhanced AMPA receptor activity increases operant alcohol self-administration and cue-induced reinstatement. Addiction biology, 2013, Volume: 18, Issue:1 Topics: Alcohol Drinking; Alcoholism; Analysis of Variance; Animals; Conditioning, Operant; Cues; Disease Models, Animal; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Linear Models; Male; Motor Activity; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Receptors, AMPA; Recurrence; Reinforcement, Psychology; Self Administration; Sucrose	2013
Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis. American journal of physiology. Gastrointestinal and liver physiology, 2013, Mar-15, Volume: 304, Issue:6 Topics: Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Hypoglycemic Agents; Ileitis; Inflammation Mediators; KATP Channels; Lymphatic Vessels; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Potassium Channels, Inwardly Rectifying; Quinoxalines; Receptors, Drug; Sulfonylurea Receptors; Trinitrobenzenesulfonic Acid; Up-Regulation	2013
Enhanced antitumor effect of YM872 and AG1296 combination treatment on human glioblastoma xenograft models. Journal of neurosurgery, 2013, Volume: 118, Issue:4 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Glioblastoma; Humans; Imidazoles; In Vitro Techniques; Mice; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Quinoxalines; Receptors, AMPA; Receptors, Platelet-Derived Growth Factor; Transplantation, Heterologous; Treatment Outcome; Tyrphostins	2013
Biological assay of a novel quinoxalinone with antimalarial efficacy on Plasmodium yoelii yoelii. Parasitology research, 2013, Volume: 112, Issue:4 Topics: Administration, Oral; Animals; Antimalarials; Biological Assay; Disease Models, Animal; Malaria; Male; Mice; Plasmodium yoelii; Quinoxalines; Survival Analysis; Treatment Outcome	2013
Effects of anti-glaucoma medications on ganglion cell survival: the DBA/2J mouse model. Vision research, 2002, Volume: 42, Issue:20 Topics: Aging; Analysis of Variance; Animals; Antihypertensive Agents; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Glaucoma; Memantine; Mice; Mice, Inbred DBA; Quinoxalines; Retinal Ganglion Cells; Timolol	2002
Alpha 2-Adrenergic stimulation is protective against ischemia-reperfusion-induced ventricular arrhythmias in vivo. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:6 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Brimonidine Tartrate; Disease Models, Animal; Electrocardiography; Female; Heart Rate; Kidney; Male; Myocardial Ischemia; Myocardial Reperfusion; Quinoxalines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sympathetic Nervous System; Tachycardia, Ventricular; Ventricular Fibrillation	2002
2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]-propionic acid (XK469) inhibition of topoisomerase IIbeta is not sufficient for therapeutic response in human Waldenstrom's macroglobulinemia xenograft model. Molecular cancer therapeutics, 2002, Volume: 1, Issue:14 Topics: Animals; Blotting, Western; Cell Division; Disease Models, Animal; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Poly(ADP-ribose) Polymerases; Quinoxalines; Time Factors; Topoisomerase II Inhibitors; Waldenstrom Macroglobulinemia	2002
Ability of NMDA and non-NMDA receptor antagonists to inhibit cerebral ischemic damage in aged rats. Brain research, 2003, Feb-21, Volume: 964, Issue:1 Topics: Aging; Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Telencephalon	2003
The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis. Neuroscience letters, 2003, Jun-05, Volume: 343, Issue:2 Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Behavior, Animal; Calcium; Cells, Cultured; Disease Models, Animal; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Forelimb; Glycine; Hand Strength; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Neurons; Psychomotor Performance; Quinoxalines; Receptors, AMPA	2003
Multiple sclerosis and glutamate. Annals of the New York Academy of Sciences, 2003, Volume: 993 Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Receptors, AMPA; Spinal Cord	2003
In vivo neuroprotective effects of ACEA 1021 confirmed by magnetic resonance imaging in ischemic stroke. European journal of pharmacology, 2003, Aug-01, Volume: 474, Issue:1 Topics: Animals; Behavior, Animal; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Subcutaneous; Magnetic Resonance Imaging; Male; Mice; Neuroprotective Agents; Psychomotor Performance; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reperfusion	2003
Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats. Brain research, 2004, Jan-02, Volume: 995, Issue:1 Topics: Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Memory Disorders; Nerve Degeneration; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Reperfusion Injury	2004
A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Cardiomyopathy, Dilated; Cricetinae; Cytoskeletal Proteins; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Enalapril; Endothelium, Vascular; Enzyme Inhibitors; Heart Failure; Hemodynamics; Male; Membrane Glycoproteins; Mesocricetus; Myocardial Contraction; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxadiazoles; Quinoxalines; Rabbits; Sarcoglycans; Ultrasonography; Vasoconstriction; Ventricular Remodeling	2004
An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52, Issue:12 Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Colitis; Dextran Sulfate; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Humans; I-kappa B Kinase; Imidazoles; Intercellular Adhesion Molecule-1; Mice; Protein Serine-Threonine Kinases; Quinoxalines; Sulfasalazine; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2003
Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, May-05, Volume: 24, Issue:18 Topics: Animals; Calcium; Cell Death; Cell Differentiation; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; Gestational Age; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Kainic Acid; Leukomalacia, Periventricular; Movement Disorders; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Topiramate; Treatment Outcome	2004
Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice. Gastroenterology, 2004, Volume: 126, Issue:5 Topics: alpha-Fetoproteins; Animals; beta Catenin; Cell Cycle Proteins; Cytoskeletal Proteins; Disease Models, Animal; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Gene Deletion; Gene Frequency; Genes, myc; Genomic Instability; Liver Neoplasms; Loss of Heterozygosity; Mice; Mice, Transgenic; Mutation; Phenotype; Quinoxalines; Trans-Activators; Transcription Factors; Transforming Growth Factor alpha	2004
NBQX or topiramate treatment after perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury. Epilepsia, 2004, Volume: 45, Issue:6 Topics: Animals; Anticonvulsants; Brain; Cell Death; Disease Models, Animal; DNA Fragmentation; Fructose; Hippocampus; Hypoxia, Brain; In Situ Nick-End Labeling; Kainic Acid; Male; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Seizures; Topiramate	2004
Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord. Experimental neurology, 2004, Volume: 187, Issue:2 Topics: Animals; Cell Count; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Spinal Cord Injuries; Time Factors	2004
Ensemble spontaneous activity in the guinea-pig cochlear nerve. Hearing research, 2004, Volume: 192, Issue:1-2 Topics: Acoustic Stimulation; Adenosine Triphosphate; Animals; Cochlear Nerve; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Furosemide; Guinea Pigs; Humans; Male; Nerve Fibers; Purinergic P2 Receptor Agonists; Quinoxalines; Receptors, Purinergic P2X; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Tinnitus	2004
Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdala neurons in a model of arthritic pain. Pain, 2004, Volume: 110, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Analysis of Variance; Animals; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kaolin; Male; Neural Inhibition; Neurons; Nociceptors; Pain; Pain Measurement; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2004
Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain. Neuropharmacology, 2004, Volume: 47, Issue:3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Male; Morphine; Narcotics; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Kainic Acid; Tetrahydroisoquinolines; Time Factors	2004
Loss of endothelial KATP channel-dependent, NO-mediated dilation of endocardial resistance coronary arteries in pigs with left ventricular hypertrophy. British journal of pharmacology, 2004, Volume: 143, Issue:2 Topics: Adenosine Triphosphate; Animals; Bradykinin; Brimonidine Tartrate; Canada; Charybdotoxin; Coronary Vessels; Disease Models, Animal; Drug Therapy, Combination; Endocardium; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Hemodynamics; Hypertrophy, Left Ventricular; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Potassium Channels; Quinoxalines; Swine; Vascular Resistance; Vasodilation	2004
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37 Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Crosses, Genetic; Dentate Gyrus; Disease Models, Animal; Down Syndrome; Evoked Potentials; Female; GABA-A Receptor Antagonists; Gene Dosage; Glycine; Hippocampus; Long-Term Potentiation; Magnesium; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Species Specificity; Trisomy	2004
Synthesis and AMPA receptor antagonistic activity of a novel 7-imidazolyl-6-trifluoromethyl quinoxalinecarboxylic acid with a substituted phenyl group and improved its good physicochemical properties by introduced CF3 group. Bioorganic & medicinal chemistry letters, 2004, Oct-18, Volume: 14, Issue:20 Topics: Animals; Brain Ischemia; Disease Models, Animal; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Neuroprotective Agents; Quinoxalines; Rats; Receptors, AMPA; Solubility; Structure-Activity Relationship	2004
Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice. Hippocampus, 2005, Volume: 15, Issue:1 Topics: 4-Aminopyridine; Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cortical Synchronization; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; Nerve Net; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Potassium Channel Blockers; Presynaptic Terminals; Quinoxalines; Synaptic Transmission	2005
Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cycloox Carcinogenesis, 2005, Volume: 26, Issue:1 Topics: Adenocarcinoma; Animals; Anticoagulants; Base Sequence; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Restriction Mapping; Trans-Activators	2005
Decreased aortic smooth muscle contraction in a rat model of multibacterial sepsis. Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:6 Topics: Animals; Aorta; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Sepsis; Soluble Guanylyl Cyclase	2004
Characterization of the tetanus toxin model of refractory focal neocortical epilepsy in the rat. Epilepsia, 2005, Volume: 46, Issue:2 Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Diazepam; Disease Models, Animal; Electroencephalography; Electromyography; Epilepsies, Partial; Exploratory Behavior; Male; Motor Activity; Neocortex; Phenytoin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetanus Toxin	2005
Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures. Neuropharmacology, 2005, Volume: 49, Issue:4 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ion Channels; Lignans; Mice; N-Methylaspartate; Neurons; Platelet Aggregation Inhibitors; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Sodium	2005
The effects of AMPA receptor antagonists in models of stroke and neurodegeneration. European journal of pharmacology, 2005, Sep-05, Volume: 519, Issue:1-2 Topics: Animals; Animals, Newborn; Anticonvulsants; Benzodiazepines; Brain; Brain Ischemia; Cell Survival; Chickens; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred Strains; Motor Neurons; Nerve Degeneration; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Retina; Seizures; Stroke	2005
PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus. Nature medicine, 2005, Volume: 11, Issue:9 Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Mice; Mice, Mutant Strains; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Thiazolidinediones	2005
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nature medicine, 2005, Volume: 11, Issue:9 Topics: Animals; Arthritis, Rheumatoid; Binding Sites; Chemotaxis, Leukocyte; Dioxoles; Disease Models, Animal; Enzyme Inhibitors; Isoenzymes; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Mice, Knockout; Molecular Sequence Data; Molecular Structure; Peritonitis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Signal Transduction; Structure-Activity Relationship; Thiazolidinediones	2005
Recurrent mossy fibers establish aberrant kainate receptor-operated synapses on granule cells from epileptic rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-07, Volume: 25, Issue:36 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Mossy Fibers, Hippocampal; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Synapses	2005
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model. Pharmacology, 2005, Volume: 75, Issue:3 Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley	2005
Acute vibration increases alpha2C-adrenergic smooth muscle constriction and alters thermosensitivity of cutaneous arteries. Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 100, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Body Temperature Regulation; Brimonidine Tartrate; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Neuromuscular Diseases; Quinolizines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Skin; Tail; Vasoconstriction; Vibration	2006
Effect of YM872, a selective and highly water-soluble AMPA receptor antagonist, in the rat kindling and rekindling model of epilepsy. European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3 Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Imidazoles; Kindling, Neurologic; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors	2006
Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503. Brain research, 2006, Feb-16, Volume: 1073-1074 Topics: Animals; Anti-Obesity Agents; Arachidonic Acid; Behavior, Animal; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Eating; Humans; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphoric Monoester Hydrolases; Pyrazines; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium	2006
Alcohol potently modulates climbing fiber-->Purkinje neuron synapses: role of metabotropic glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Feb-15, Volume: 26, Issue:7 Topics: Alanine; Animals; Aspartic Acid; Disease Models, Animal; Ethanol; Long-Term Synaptic Depression; Male; Nerve Fibers; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses; Xanthenes	2006
Evidence for a role of inducible nitric oxide synthase in gastric relaxation of mdx mice. Neurogastroenterology and motility, 2006, Volume: 18, Issue:6 Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred mdx; Muscle Relaxation; Muscle, Smooth; Muscular Dystrophy, Duchenne; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Organ Culture Techniques; Oxadiazoles; Quinoxalines; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach; Vasoactive Intestinal Peptide	2006
A rat model for acute rise in intraocular pressure: immune modulation as a therapeutic strategy. American journal of ophthalmology, 2006, Volume: 141, Issue:6 Topics: Acute Disease; Animals; Antihypertensive Agents; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Dizocilpine Maleate; Glatiramer Acetate; Immunization; Injections; Intraocular Pressure; Male; Neuroprotective Agents; Ocular Hypertension; Optic Nerve Diseases; Peptides; Quinoxalines; Rats; Rats, Inbred Lew; Retinal Ganglion Cells; Vaccination	2006
Mechanisms underlying lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat aorta. British journal of pharmacology, 2006, Volume: 149, Issue:7 Topics: Animals; Aorta, Thoracic; Brimonidine Tartrate; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Lysophosphatidylcholines; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Potassium; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Quinoxalines; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Receptors, G-Protein-Coupled; RNA, Messenger; Up-Regulation; Vanadates; Vasoconstriction; Vasoconstrictor Agents	2006
Neuroprotective effects of brimonidine treatment in a rodent model of ischemic optic neuropathy. Experimental eye research, 2007, Volume: 84, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Axons; Benzoxazines; Brimonidine Tartrate; Cell Survival; Coloring Agents; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Neuroprotective Agents; Ophthalmic Solutions; Optic Neuropathy, Ischemic; Oxazines; Quinoxalines; Rats; Rats, Long-Evans; Retinal Ganglion Cells	2007
The growth factor response in ischemic rat retina and superior colliculus after brimonidine pre-treatment. Brain research bulletin, 2006, Dec-11, Volume: 71, Issue:1-3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Axons; Brain Ischemia; Brimonidine Tartrate; Cytoprotection; Disease Models, Animal; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Growth Factor; Retinal Ganglion Cells; RNA, Messenger; Superior Colliculi; Up-Regulation	2006
Modulation of isolated N-methyl-d-aspartate receptor response under hyperbaric conditions. The European journal of neuroscience, 2006, Volume: 24, Issue:12 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Helium; High Pressure Neurological Syndrome; Hippocampus; In Vitro Techniques; Magnesium; Male; Pressure; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine	2006
Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation. Molecular and cellular neurosciences, 2007, Volume: 34, Issue:4 Topics: Animals; Blotting, Western; Cannabinoids; Demyelinating Diseases; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; Mice; Multiple Sclerosis, Chronic Progressive; Neuroprotective Agents; Quinoxalines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Cord	2007
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats. The Journal of physiology, 2007, Jun-01, Volume: 581, Issue:Pt 2 Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemorrhage; Injections, Spinal; Nitric Oxide; Oxadiazoles; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Sympathetic Nervous System	2007
Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant. European journal of pharmacology, 2007, Jun-01, Volume: 563, Issue:1-3 Topics: Animals; Basal Ganglia; Caudate Nucleus; Cricetinae; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Microinjections; Movement; Muscle Contraction; Mutation; Posture; Putamen; Pyrrolidinones; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Valine	2007
Protective effect of PNQX on motor units and muscle property after sciatic nerve crush in neonatal rats. Pharmacological research, 2007, Volume: 55, Issue:5 Topics: Animals; Animals, Newborn; Axotomy; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Male; Motor Neurons; Muscle Contraction; Muscle Fatigue; Muscle Relaxation; Muscle Strength; Muscle, Skeletal; Neuroprotective Agents; Organ Size; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Sciatic Neuropathy; Time Factors	2007
Dopamine-dependent long term potentiation in the dorsal striatum is reduced in the R6/2 mouse model of Huntington's disease. Neuroscience, 2007, Jun-08, Volume: 146, Issue:4 Topics: Animals; Benzazepines; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Huntingtin Protein; Huntington Disease; Long-Term Potentiation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Quinoxalines; Time Factors	2007
Neuroprotective effect of topically applied brimonidine tartrate 0.2% in endothelin-1-induced optic nerve ischaemia model. Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:6 Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Apoptosis; Brimonidine Tartrate; Cell Count; Disease Models, Animal; Endothelin-1; Infusion Pumps, Implantable; Neuroprotective Agents; Optic Neuropathy, Ischemic; Quinoxalines; Rabbits; Retina; Retinal Ganglion Cells	2007
Type 1 diabetes and hypercholesterolaemia reveal the contribution of endothelium-derived hyperpolarizing factor to endothelium-dependent relaxation of the rat aorta. Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:2 Topics: Acetylcholine; Animals; Aorta, Thoracic; Apamin; Biological Factors; Blood Glucose; Body Weight; Charybdotoxin; Cholesterol; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hypercholesterolemia; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Oxidative Stress; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Superoxides; Vasodilation; Vasodilator Agents	2008
Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis. European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3 Topics: Animals; Colitis; Cyclic GMP; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Soluble Guanylyl Cyclase	2008
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats. British journal of pharmacology, 2008, Volume: 153, Issue:4 Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Glyburide; Guanylate Cyclase; Hemoglobins; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones	2008
Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology, 2008, Volume: 54, Issue:3 Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Brain; Depression; Disease Models, Animal; Drug Administration Routes; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hindlimb Suspension; Injections, Intraventricular; Lithium Compounds; Mice; Mice, Inbred C57BL; Protein Transport; Quinoxalines; Receptors, AMPA; Swimming; Time Factors	2008
Drug modification of angiogenesis in a rat cornea model. Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:1 Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Corneal Neovascularization; Corneal Stroma; Disease Models, Animal; Drug Implants; Fibroblast Growth Factor 2; Latanoprost; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Timolol	2008
Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Neuron, 2008, Jan-24, Volume: 57, Issue:2 Topics: Acoustic Stimulation; Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Calcium; Disease Models, Animal; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Hair Cells, Auditory; Hearing Loss, Sensorineural; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Neurons; Quinoxalines; Reflex, Startle; Seizures; Spiral Ganglion	2008
Anterior cingulate cortex modulates visceral pain as measured by visceromotor responses in viscerally hypersensitive rats. Gastroenterology, 2008, Volume: 134, Issue:2 Topics: Albumins; Anaphylaxis; Animals; Colon; Disease Models, Animal; Electric Stimulation; Glutamic Acid; Gyrus Cinguli; Hypersensitivity; Male; Motor Cortex; Neurons; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Viscera	2008
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury. Neurological research, 2008, Volume: 30, Issue:4 Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ion Channels; Kynurenic Acid; Male; Microglia; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Blockers; Time Factors; Treatment Outcome; Up-Regulation; Valine	2008
Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes. Circulation, 2008, Mar-11, Volume: 117, Issue:10 Topics: Animals; Apolipoproteins E; Atherosclerosis; Class Ib Phosphatidylinositol 3-Kinase; Disease Models, Animal; Humans; Inflammation; Intramolecular Oxidoreductases; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoinositide-3 Kinase Inhibitors; Prostaglandin-E Synthases; Quinoxalines; Receptors, LDL; Thiazolidinediones	2008
Intrathecally injected morphine inhibits inflammatory paw edema: the involvement of nitric oxide and cyclic-guanosine monophosphate. Anesthesia and analgesia, 2008, Volume: 106, Issue:3 Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Guanylate Cyclase; Inflammation; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Neutrophil Infiltration; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Peroxidase; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Sildenafil Citrate; Spinal Cord; Sulfones; Time Factors	2008
Suppressive effects of a quinoxaline-analogue (Rob 803) on pathogenic immune mechanisms in collagen-induced arthritis. Clinical and experimental immunology, 2008, Volume: 152, Issue:1 Topics: Administration, Oral; Animals; Antirheumatic Agents; Apoptosis; Arthritis, Experimental; Cell Proliferation; Cells, Cultured; Collagen Type II; Disease Models, Animal; Dose-Response Relationship, Immunologic; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Female; Immunoglobulin G; Immunosuppressive Agents; Injections, Subcutaneous; Lymph Nodes; Lymphocyte Activation; Macrophages; Nitrogen Dioxide; Quinoxalines; Rats; Rats, Inbred Strains; T-Lymphocytes	2008
Deficiency of neural cell adhesion molecule or its polysialylation modulates pharmacological effects of the AMPA receptor antagonist NBQX. Neuroscience, 2008, Apr-09, Volume: 152, Issue:4 Topics: Analysis of Variance; Animals; Ataxia; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Cell Adhesion Molecules; Pentylenetetrazole; Quinoxalines; Seizures; Sialyltransferases	2008
The novel small molecule drug Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders. Annals of the rheumatic diseases, 2009, Volume: 68, Issue:1 Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Collagen; Cytokines; Disease Models, Animal; Immunosuppressive Agents; Indoles; Mice; Mice, Mutant Strains; Multiple Sclerosis; Quinoxalines; Rats; Reactive Oxygen Species; Treatment Outcome	2009
Retinal ganglion cell neuroprotection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments. Experimental eye research, 2008, Volume: 86, Issue:5 Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Neuroprotective Agents; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells	2008
Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nature neuroscience, 2008, Volume: 11, Issue:6 Topics: Animals; Behavior, Animal; Disease Models, Animal; Electroporation; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Patch-Clamp Techniques; Photic Stimulation; Piperazines; Quinoxalines; Retinal Bipolar Cells; Retinal Degeneration; Retinal Ganglion Cells; Rhodopsin; Time Factors; Vision, Ocular; Visual Pathways	2008
Differential effect of NR2A and NR2B subunit selective NMDA receptor antagonists on striato-pallidal neurons: relationship to motor response in the 6-hydroxydopamine model of parkinsonism. Journal of neurochemistry, 2008, Volume: 106, Issue:2 Topics: Adrenergic Agents; Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Antagonists; Globus Pallidus; Male; Microdialysis; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Phenols; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley	2008
Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Adenosine A3 Receptor Antagonists; Animals; Binding, Competitive; Brain Ischemia; Cattle; Cell Membrane; Cerebral Cortex; Disease Models, Animal; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Protein Binding; Quinoxalines; Rats; Receptor, Adenosine A3; Rhodopsin; Structural Homology, Protein; Structure-Activity Relationship; Triazoles; Xanthines	2008
Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, May-21, Volume: 28, Issue:21 Topics: Animals; Animals, Newborn; Corpus Striatum; Dendritic Spines; Disease Models, Animal; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medial Forebrain Bundle; Mice; Mice, Transgenic; Nerve Net; Neurons; Oxidopamine; Parkinson Disease; Patch-Clamp Techniques; Quinoxalines; Receptors, Dopamine D1; Receptors, Dopamine D2; Sympatholytics; Synapses	2008
[Staphylococcal necrotic suppurative encephalomeningitis in mice as a chemotherapeutic model]. Antibiotiki, 1982, Volume: 27, Issue:5 Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Meningoencephalitis; Mice; Necrosis; Quinoxalines; Staphylococcal Infections; Staphylococcus aureus; Time Factors	1982
[The effect of absorbent materials with drugs on wound healing]. Khirurgiia, 1993, Issue:11 Topics: Administration, Topical; Amylases; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Disease Models, Animal; Drug Carriers; Drug Combinations; Escherichia coli Infections; Evaluation Studies as Topic; Guinea Pigs; Peptide Hydrolases; Quinoxalines; Sorption Detoxification; Time Factors; Wound Healing; Wound Infection	1993
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice. European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2 Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission	1994
Alpha 2-adrenoceptor mediated inhibition of [3H]dopamine release from nucleus accumbens slices and monoamine levels in a rat model for attention-deficit hyperactivity disorder. Neurochemical research, 1995, Volume: 20, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antihypertensive Agents; Attention Deficit Disorder with Hyperactivity; Biogenic Monoamines; Brimonidine Tartrate; Disease Models, Animal; Dopamine; Hypertension; In Vitro Techniques; Male; Neurons; Norepinephrine; Nucleus Accumbens; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-2; Tritium	1995
Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models. Epilepsy research, 1993, Volume: 15, Issue:3 Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Kainic Acid; Male; Mice; Pentylenetetrazole; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Seizures	1993
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury	1994
Hypoxia-ischemia in the neonatal rat brain: histopathology after post-treatment with NMDA and non-NMDA receptor antagonists. Biology of the neonate, 1994, Volume: 66, Issue:4 Topics: Animals; Animals, Newborn; Brain Damage, Chronic; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Hypoxia, Brain; Injections, Intraperitoneal; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Severity of Illness Index; Treatment Outcome	1994
Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists. Brain research, 1993, Nov-05, Volume: 627, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Biphenyl Compounds; Disease Models, Animal; Glutamates; Glutamic Acid; Immunohistochemistry; Lidocaine; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord	1993
Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat. Epilepsy research, 1993, Volume: 15, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Epilepsy; Female; Lamotrigine; Male; Motor Activity; Phenytoin; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Triazines	1993
Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11 Topics: Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Piperazines; Quinoxalines; Rats; Rats, Inbred F344; Time Factors; Wounds, Nonpenetrating	1996
Intrastriatal DNQX induces rotation and pallidal Fos in the 6-OHDA model of Parkinson's disease. Neuroreport, 1995, Dec-15, Volume: 6, Issue:18 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Rotation	1995
Effect of the novel high-affinity glycine-site N-methyl-D-aspartate antagonist ACEA-1021 on 125I-MK-801 binding after subdural hematoma in the rat: an in vivo autoradiographic study. Journal of neurosurgery, 1996, Volume: 85, Issue:4 Topics: Animals; Autoradiography; Brain; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hematoma, Subdural; Humans; Male; Quinoxalines; Rats; Rats, Sprague-Dawley	1996
Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia. European journal of pharmacology, 1996, Aug-29, Volume: 310, Issue:2-3 Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Gerbillinae; Indazoles; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Quinoxalines	1996
The ability of two cooked food mutagens to induce aberrant crypt foci in mice. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1997, Volume: 6, Issue:1 Topics: Analysis of Variance; Animals; Azoxymethane; Carcinogens; Colon; Cooking; Deoxyguanosine; Diet; Disease Models, Animal; Female; Food, Fortified; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Mice; Mice, Inbred C57BL; Mutagens; Quinoxalines; Reference Values; Weight Gain	1997
Delayed antagonism of AMPA/kainate receptors reduces long-term functional deficits resulting from spinal cord trauma. Experimental neurology, 1997, Volume: 145, Issue:2 Pt 1 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Immunohistochemistry; Microinjections; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Serotonin; Spinal Cord Injuries; Time Factors	1997
Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain. Pain, 1998, Volume: 74, Issue:2-3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Nociceptors; Pain, Postoperative; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Metabotropic Glutamate; Spinal Cord	1998
A novel AMPA receptor antagonist, YM872, reduces infarct size after middle cerebral artery occlusion in rats. Brain research, 1998, May-18, Volume: 793, Issue:1-2 Topics: Animals; Arterial Occlusive Diseases; Blood Gas Analysis; Body Temperature; Brain; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazoles; Infusions, Intravenous; Kidney; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors	1998
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18 Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E	1998
[Glutamate neurotoxicity during spinal cord ischemia--neuroprotective effects of glutamate receptor antagonists]. The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 1998, Volume: 46, Issue:9 Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Ischemia; Neuroprotective Agents; Quinoxalines; Rabbits; Spinal Cord	1998
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy. British journal of pharmacology, 1998, Volume: 125, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium	1998
Neuroprotective effects depend on the model of focal ischemia following middle cerebral artery occlusion. European journal of pharmacology, 1998, Dec-04, Volume: 362, Issue:2-3 Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Electrocoagulation; Immunosuppressive Agents; Injections, Intraperitoneal; Injections, Intravenous; Intracranial Embolism and Thrombosis; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Tacrolimus	1998
Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration. Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:1 Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Axons; Brimonidine Tartrate; Cell Count; Cell Survival; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Nerve Degeneration; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Optic Nerve Injuries; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Retinal Ganglion Cells; Timolol; Yohimbine	1999
N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists. Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Disease Models, Animal; Electroshock; Hydrobromic Acid; Hydrochloric Acid; Hydroxy Acids; Inhibitory Concentration 50; Mice; N-Methylaspartate; Organophosphonates; Quinoxalines	1999
The effect of latanoprost and brimonidine on rabbit subconjunctival fibroblasts. Journal of glaucoma, 1999, Volume: 8, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cell Count; Cell Division; Conjunctiva; Disease Models, Animal; Fibroblasts; Glaucoma; Intraocular Pressure; Latanoprost; Microfilament Proteins; Ophthalmic Solutions; Proliferating Cell Nuclear Antigen; Prostaglandins F, Synthetic; Quinoxalines; Rabbits	1999
The neuroprotective effect of the novel AMPA receptor antagonist PD152247 (PNQX) in temporary focal ischemia in the rat. Stroke, 1999, Volume: 30, Issue:7 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hypothermia, Induced; Infusions, Intravenous; Ischemic Attack, Transient; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA	1999
Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat. Brain research, 1999, Oct-09, Volume: 844, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bee Venoms; Cats; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; N-Methylaspartate; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	1999
Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nature medicine, 2000, Volume: 6, Issue:1 Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Guinea Pigs; Motor Neurons; Multiple Sclerosis; Muscle Tonus; Myelin Basic Protein; Neurons; Organophosphonates; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; Receptors, Kainic Acid; Recurrence; Spinal Cord; T-Lymphocytes	2000
Glutamate excitotoxicity in a model of multiple sclerosis. Nature medicine, 2000, Volume: 6, Issue:1 Topics: Animals; Axons; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred Strains; Multiple Sclerosis; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; T-Lymphocytes	2000
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists. Experimental neurology, 2000, Volume: 161, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Electroencephalography; Energy Metabolism; Epilepsy; Excitatory Amino Acid Antagonists; Glucose; Homocysteine; Injections, Intraventricular; Male; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures	2000
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury. Brain research, 2000, Mar-17, Volume: 859, Issue:1 Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine	2000
Blocking the glycine-binding site of NMDA receptors prevents the progression of ischemic pathology induced by bilateral carotid artery occlusion in spontaneously hypertensive rats. Brain research, 2000, Jul-21, Volume: 871, Issue:2 Topics: Animals; Binding Sites; Body Temperature; Body Water; Brain Ischemia; Carotid Artery Thrombosis; Disease Models, Animal; Glycine; Male; Motor Activity; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, N-Methyl-D-Aspartate; Survival Rate	2000
Glutamatergic drugs exacerbate symptomatic behavior in a transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder. Brain research, 2000, Sep-15, Volume: 877, Issue:1 Topics: Animals; Cerebral Cortex; Comorbidity; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Limbic System; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Motor Activity; Obsessive-Compulsive Disorder; Quinoxalines; Seizures; Tourette Syndrome	2000
Aberrant neuronal physiology in the basal nucleus of the amygdala in a model of chronic limbic epilepsy. Neuroscience, 2000, Volume: 101, Issue:2 Topics: Action Potentials; Amygdala; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Kindling, Neurologic; Neural Pathways; Neurons; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Valine	2000
Increased noradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder--the spontaneously hypertensive rat. Behavioural brain research, 2000, Dec-20, Volume: 117, Issue:1-2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Brimonidine Tartrate; Disease Models, Animal; Dopamine; Down-Regulation; Hypertension; Idazoxan; In Vitro Techniques; Male; Models, Neurological; Norepinephrine; Prefrontal Cortex; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Long-Evans; Receptors, Adrenergic, alpha-2	2000
Modifying effects of propolis on MeIQx promotion of rat hepatocarcinogenesis and in a female rat two-stage carcinogenesis model after multiple carcinogen initiation. Nutrition and cancer, 2000, Volume: 37, Issue:2 Topics: Alkylating Agents; Animals; Carcinogens; Diethylnitrosamine; Disease Models, Animal; Ethanol; Female; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Organ Size; Precancerous Conditions; Propolis; Quinoxalines; Random Allocation; Rats; Rats, Inbred F344; Water	2000
Glutamate excitotoxicity--a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis? Journal of neural transmission. Supplementum, 2000, Issue:60 Topics: Animals; Axons; Cell Death; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutaminase; Humans; Mice; Mice, Inbred Strains; Multiple Sclerosis; Myelitis; Neuroprotective Agents; Neurotoxins; Oligodendroglia; Quinoxalines; Receptors, AMPA	2000
Mechanisms that produce nitric oxide-mediated relaxation of cerebral arteries during atherosclerosis. Stroke, 2001, Volume: 32, Issue:3 Topics: Animals; Basilar Artery; Cerebral Arteries; Cholesterol; Diet, Atherogenic; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Intracranial Arteriosclerosis; Macaca fascicularis; Male; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Papaverine; Quinoxalines; Vasoconstriction; Vasodilation; Vasodilator Agents	2001
[Neuroprotection. Bases and possibilities of a future clinical use]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Apoptosis; Brimonidine Tartrate; Clinical Trials as Topic; Disease Models, Animal; Dopamine Agents; Eye Diseases; Forecasting; Glaucoma; Humans; Memantine; Neuroprotective Agents; Optic Neuritis; Quinoxalines; Retinal Diseases; Visual Fields	2001
The AMPA receptor/Na(+) channel blocker BIIR 561 CL is protective in a model of global cerebral ischaemia. European journal of pharmacology, 2001, Jun-15, Volume: 421, Issue:3 Topics: Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Male; Neuroprotective Agents; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sodium Channel Blockers; Survival Rate	2001
Neuroprotective effect of alpha(2) agonist (brimonidine) on adult rat retinal ganglion cells after increased intraocular pressure. Brain research, 2001, Sep-21, Volume: 913, Issue:2 Topics: Adrenergic alpha-Antagonists; Age Factors; Animals; Brimonidine Tartrate; Cell Count; Cell Survival; Disease Models, Animal; Female; Glaucoma; Intraocular Pressure; Nerve Degeneration; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Retinal Ganglion Cells; Time Factors	2001
[Prospects for neuroprotective glaucoma therapy]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:10 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Apoptosis; Betaxolol; Brain-Derived Neurotrophic Factor; Brimonidine Tartrate; Calcium Channel Blockers; Disease Models, Animal; Dopamine Agents; Glaucoma; Glaucoma, Open-Angle; Haplorhini; Humans; Memantine; Neuroprotective Agents; Nimodipine; Nitric Oxide Synthase; Quinoxalines; Receptors, N-Methyl-D-Aspartate	2001
Dual effect of local application of nitric oxide donors in a model of incision pain in rats. European journal of pharmacology, 2002, Apr-19, Volume: 441, Issue:1-2 Topics: Animals; Disease Models, Animal; Diuretics, Osmotic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hindlimb; Hyperalgesia; Isosorbide; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Nitrites; Ointments; Oxadiazoles; Pain Threshold; Pain, Postoperative; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Time Factors	2002
Effect of hyaluronic acid on intraocular pressure in rats. Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:7 Topics: Animals; Anterior Chamber; Antihypertensive Agents; Brimonidine Tartrate; Disease Models, Animal; Hyaluronic Acid; Injections; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Timolol; Tonometry, Ocular	2002
[Comparative studies of the therapeutic value of metronidazole and carbadox in flagellata infections of mice]. Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie, 1976, Volume: 131, Issue:8 Topics: Animals; Carbadox; Disease Models, Animal; Drug Evaluation, Preclinical; Giardiasis; Metronidazole; Mice; Quinoxalines; Trichomonas Infections	1976
The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice. Science (New York, N.Y.), 1992, Jul-17, Volume: 257, Issue:5068 Topics: Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Epilepsy, Absence; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Picrotoxin; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate	1992
Repeated treatment with quinolones potentiates the seizures induced by aminophylline in genetically epilepsy-prone rats. General pharmacology, 1992, Volume: 23, Issue:5 Topics: Aminophylline; Animals; Cerebral Cortex; Disease Models, Animal; Drug Synergism; Electroencephalography; Epilepsy; Quinoxalines; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Seizures	1992
The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model. Brain research, 1992, May-15, Volume: 580, Issue:1-2 Topics: Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Infusions, Intravenous; Ischemic Attack, Transient; Male; Quinoxalines; Rats; Rats, Inbred Strains	1992
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease. Journal of neural transmission. Parkinson's disease and dementia section, 1991, Volume: 3, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Callithrix; Disease Models, Animal; Drug Synergism; Ibotenic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra	1991