quinoxalines has been researched along with Cancer of Colon in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.50) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 15 (46.88) | 29.6817 |
| 2010's | 8 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bulusu, G; Bung, N; Ghosh, A; Haldar, D; Nakhi, A; Pal, M; Seerapu, GPK; Sengupta, A; Shivaji Ramarao, EVV | 1 |
| Cross, AJ; Harper, G; Hartman, TJ; Laio, J; Lazarus, P; Lesko, SM; Miller, PE; Muscat, JE; Sinha, R; Zhu, J | 1 |
| Debnath, B; Garofalo, A; Grande, F; Imada, T; Masuda, M; Neamati, N; Oshima, T; Xu, S | 1 |
| Helmus, DS; Li, L; Thompson, CL; Tucker, TC; Zelenskiy, S | 1 |
| Futakuchi, M; Hirose, M; Kawabe, M; Shirai, T; Tamano, S | 1 |
| Bendaly, J; Hein, DW; Metry, KJ; Neale, JR; Pierce, WM; Smith, NB | 1 |
| Inoue, T; Ishii, Y; Kodama, Y; Mitsumori, K; Nishikawa, A; Nohmi, T; Okamura, T; Suzuki, Y; Tasaki, M; Umemura, T | 1 |
| El-Khatib, M; Gali-Muhtasib, H; Geara, F; Haddadin, MJ | 1 |
| Bode, AM; Cho, YY; Dong, Z; Kim, DJ; Kim, JE; Kim, MO; Lee, MH; Lee, SY; Li, Y; Reddy, K | 1 |
| Dong, MS; Gong, YD; Lee, SB; Park, YI | 1 |
| Kohno, H; Sugie, S; Suzuki, R; Takahashi, M; Tanaka, T; Wakabayashi, K | 1 |
| Diab-Assaf, M; Gali-Muhtasib, HU; Haddadin, MJ | 1 |
| Fukushima, S; Ichihara, T; Morimura, K; Nakae, D; Totsuka, Y; Wanibuchi, H; Wei, M | 1 |
| Hirose, M; Imazawa, T; Ishii, Y; Kanki, K; Kitamura, Y; Kuroiwa, Y; Nishikawa, A; Umemura, T | 1 |
| Bieberschulte, W; Gille, L; Jurek, D; Marian, B; Nohl, H; Rohr-Udilova, N; Schulte-Hermann, R | 1 |
| Gali-Muhtasib, H; Geara, F; Haddadin, M; Haykal, J; Itani, W | 1 |
| Bisagni, E; Bissery, MC; Fan, E; Lavelle, F; Nguyen, CH; Riou, JF; Vrignaud, P | 1 |
| Inoue, R; Kakiuchi, H; Makino, H; Nagao, M; Sugimura, T; Ushijima, T | 1 |
| Dingley, KH; Frantz, CE; Garner, RC; Mauthe, RJ; Shen, N; Turteltaub, KW; Vogel, JS | 1 |
| Dunn, DM; Landers, M; Miller, MF; Pence, BC; Shen, CL | 1 |
| Degawa, M; Konno, Y; Moore, MA; Nakashita, K; Sekine, K; Takasuka, N; Tsuda, H; Uehara, N | 1 |
| Archer, CL; Haas, GP; Jones, RF; Morse, P; Shirai, T; Wang, CY | 1 |
| Futakuchi, M; Hirose, M; Kimoto, N; Kono, T; Lin, C; Nishibe, S; Shirai, T; Yamaguchi, T | 1 |
| Furukawa, F; Mori, H; Mori, I; Nishikawa, A; Takahashi, M; Tanakamaru, Z | 1 |
| Chen, BD; Lin, H; Liu, XY; Nakeff, A; Subramanian, B; Valeriote, F | 1 |
| Nakeff, A; Pisano, M; Sahay, N; Subramanian, B | 1 |
| Furukawa, F; Hirose, M; Koide, A; Miyauchi, M; Mori, Y; Nishikawa, A; Okazaki, K; Son, HY | 1 |
| Assaad, C; Diab-Assef, M; Gali-Muhtasib, HU; Haddadin, MJ; Yared, P | 1 |
| Ana'nev, VS; Malakhova, VA; Ponomareva, TR | 1 |
| Bylund, DB; Ray-Prenger, C; Turner, JT | 1 |
| Bylund, DB; Jones, SB; Toews, ML; Turner, JT | 1 |
| Denis, C; Murat, JC; Paris, H | 1 |
32 other study(ies) available for quinoxalines and Cancer of Colon
| Article | Year |
|---|---|
A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; HCT116 Cells; Humans; Molecular Structure; Quinoxalines; Sirtuin 1; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2017 |
Meat-related compounds and colorectal cancer risk by anatomical subsite.
Topics: Aged; Animals; Benzo(a)pyrene; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Cooking; Feeding Behavior; Female; Humans; Imidazoles; Logistic Models; Male; Meat; Meat Products; Middle Aged; Nitrates; Nitrites; Pennsylvania; Poultry; Quinoxalines; Rectal Neoplasms; Risk Factors; Surveys and Questionnaires | 2013 |
Stabilization of MDA-7/IL-24 for colon cancer therapy.
Topics: Aged; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Down-Regulation; fas Receptor; Female; G1 Phase Cell Cycle Checkpoints; Humans; Hydrazines; Interleukins; Male; Molecular Docking Simulation; Prognosis; Quinoxalines; Recombinant Proteins; Survival; Tumor Suppressor Protein p53; Up-Regulation | 2013 |
Red meat-derived heterocyclic amines increase risk of colon cancer: a population-based case-control study.
Topics: Aged; Amines; Case-Control Studies; Colonic Neoplasms; Confidence Intervals; Cooking; Female; Humans; Logistic Models; Male; Meat; Middle Aged; Mutagens; Nutrition Assessment; Odds Ratio; Polycyclic Aromatic Hydrocarbons; Quinoxalines; Risk Factors; Surveys and Questionnaires | 2013 |
Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesi
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Chitin; Chitosan; Colonic Neoplasms; Diethylnitrosamine; Female; Glutathione Peroxidase; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Animal; Organ Size; Quinoxalines; Rats; Rats, Inbred F344 | 2008 |
Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
Topics: Acetylation; Animals; Animals, Congenic; Arylamine N-Acetyltransferase; Carcinogens; Colonic Neoplasms; Deoxyguanosine; DNA Adducts; Female; Gene Targeting; Genetic Predisposition to Disease; Imidazoles; Liver Neoplasms; Mutagens; Polymorphism, Genetic; Quinoxalines; Rats; Rats, Inbred F344; Rats, Inbred WKY; Time Factors | 2009 |
Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice.
Topics: Animals; Cocarcinogenesis; Colonic Neoplasms; Dextran Sulfate; Escherichia coli Proteins; Male; Mice; Mice, Transgenic; Mutagens; Pentosyltransferases; Quinoxalines; Tumor Suppressor Protein p53 | 2010 |
Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21.
Topics: Antineoplastic Agents; Carcinoma; Cell Death; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Drug Evaluation, Preclinical; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Oxygen; Quinoxalines; Tumor Suppressor Protein p53 | 2010 |
Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 7; Cell Proliferation; Colonic Neoplasms; Gene Knockdown Techniques; Humans; Indolizines; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Quinoxalines; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2012 |
2,3,6-Trisubstituted quinoxaline derivative, a small molecule inhibitor of the Wnt/beta-catenin signaling pathway, suppresses cell proliferation and enhances radiosensitivity in A549/Wnt2 cells.
Topics: Antineoplastic Agents; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Humans; Lung Neoplasms; Quinoxalines; Radiation Tolerance; Radiation-Sensitizing Agents; Respiratory Mucosa; Wnt Proteins; Wnt Signaling Pathway | 2013 |
Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cycloox
Topics: Adenocarcinoma; Animals; Anticoagulants; Base Sequence; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclooxygenase 2; Cytoskeletal Proteins; Dextran Sulfate; Disease Models, Animal; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Restriction Mapping; Trans-Activators | 2005 |
Quinoxaline 1,4-dioxides induce G2/M cell cycle arrest and apoptosis in human colon cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Division; Cells, Cultured; Colonic Neoplasms; Cyclin B; Extracellular Signal-Regulated MAP Kinases; Humans; Proto-Oncogene Proteins c-bcl-2; Quinoxalines; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3,8-dimethylimidazo [4,5-f ]quinoxaline (MeIQx) in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cell Proliferation; Colon; Colonic Neoplasms; Deoxyguanosine; Diet; DNA Adducts; Female; Glutathione Transferase; Humans; Lactation; Liver; Liver Neoplasms, Experimental; Male; Milk, Human; Placenta; Precancerous Conditions; Pregnancy; Quinoxalines; Rats; Rats, Inbred F344 | 2004 |
Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diet; Drug Therapy, Combination; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Quinolines; Quinoxalines | 2005 |
Ubiquinol and the papaverine derivative caroverine prevent the expression of tumour- promoting factors in adenoma and carcinoma colon cancer cells induced by dietary fat.
Topics: Adenoma; Carcinoma; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dietary Fats; Gene Expression Regulation, Neoplastic; Humans; Linoleic Acids; Lipid Peroxides; Organic Chemicals; Pyrazoles; Quinoxalines; Sulfonamides; Tumor Cells, Cultured; Ubiquinone; Vascular Endothelial Growth Factor A | 2005 |
Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Comet Assay; DNA Damage; Flow Cytometry; Humans; Hypoxia; In Situ Nick-End Labeling; Intestines; Oxygen; Quinoxalines; Radiation Oncology; Radiation-Sensitizing Agents | 2007 |
Synthesis and biological evaluation of amino-substituted benzo[f]pyrido[4,3-b] and pyrido[3,4-b]quinoxalines: a new class of antineoplastic agents.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Colonic Neoplasms; Drug Screening Assays, Antitumor; Leukemia P388; Mice; Mice, Inbred C57BL; Quinoxalines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1995 |
Genetic alterations in HCA-induced tumors.
Topics: Animals; Carcinogens; Colonic Neoplasms; Diet; Female; Food; Genes, p53; Genes, ras; Humans; Imidazoles; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mutagenesis; Mutagens; Neoplasms, Experimental; Point Mutation; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Stomach Neoplasms | 1995 |
MeIQx-DNA adduct formation in rodent and human tissues at low doses.
Topics: Animals; Colonic Neoplasms; DNA Adducts; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Humans; Liver; Quinoxalines; Rats; Rats, Inbred F344; Tissue Distribution | 1997 |
Feeding of a well-cooked beef diet containing a high heterocyclic amine content enhances colon and stomach carcinogenesis in 1,2-dimethylhydrazine-treated rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cattle; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cooking; Male; Meat Products; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Stomach Neoplasms | 1998 |
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Experimental; Male; Phosphodiesterase Inhibitors; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1999 |
Carcinogenicity of the N-hydroxy derivative of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 2-amino-3, 8-dimethyl-imidazo[4,5-f]quinoxaline and 3, 2'-dimethyl-4-aminobiphenyl in the rat.
Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Body Weight; Carcinogens; Carcinoma, Transitional Cell; Colonic Neoplasms; Hyperplasia; Imidazoles; Male; Mutagens; Prostatic Neoplasms; Pyridines; Quinoxalines; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms | 2000 |
Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats.
Topics: Animals; Biological Assay; Body Weight; Carcinogens; Carcinoma; Colonic Neoplasms; Diet; Drugs, Chinese Herbal; Female; Fibroadenoma; Furans; Glucosides; Glutathione Transferase; Imidazoles; Liver; Male; Mammary Neoplasms, Experimental; Pancreatic Neoplasms; Quinoxalines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Time Factors | 2000 |
Essential similarities between spontaneous and MeIQx-promoted aberrant crypt foci in the F344 rat colon.
Topics: Animals; Carcinogens; Colonic Neoplasms; Genes, ras; Male; Mutagens; Mutation; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Quinoxalines; Rats; Rats, Inbred F344; Tumor Suppressor Protein p53 | 2001 |
Mitotic arrest induced by XK469, a novel antitumor agent, is correlated with the inhibition of cyclin B1 ubiquitination.
Topics: Amsacrine; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Division; Colonic Neoplasms; Cyclin B; Cyclin B1; Flow Cytometry; Humans; Immunoblotting; Mitosis; Peptide Hydrolases; Quinoxalines; Spindle Apparatus; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitin | 2002 |
Painting with a molecular brush: genomic/proteomic interfacing to define the drug action profile of novel solid-tumor selective anticancer agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Gene Expression Profiling; Humans; MAP Kinase Signaling System; Multigene Family; Neoplasm Proteins; Proteome; Quinoxalines | 2002 |
Enhancement by cigarette smoke exposure of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis in close association with elevation of hepatic CYP1A2.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Immunoblotting; Liver; Liver Neoplasms, Experimental; Male; Mutagens; Organ Size; Quinoxalines; Rats; Rats, Inbred F344; Smoking | 2002 |
Quinoxaline 1,4-dioxides: hypoxia-selective therapeutic agents.
Topics: Aerobiosis; Antineoplastic Agents; Cell Hypoxia; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Kinetics; Quinoxalines; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
[Pharmacokinetics of dioxidine in oncological patients in the postoperative period].
Topics: Anti-Infective Agents; Colonic Neoplasms; Drug Administration Schedule; Escherichia coli Infections; Humans; Infusions, Intravenous; Postoperative Care; Quinoxalines; Surgical Wound Infection; Time Factors | 1989 |
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Line; Clonidine; Colforsin; Colonic Neoplasms; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1985 |
Alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production.
Topics: Adenine; Adenocarcinoma; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Humans; Kinetics; Norepinephrine; Quinoxalines; Receptors, Adrenergic, alpha | 1987 |
Hormonal control of fructose 2,6-bisphosphate concentration in the HT29 human colon adenocarcinoma cell line. Alpha 2-adrenergic agonists counteract effect of vasoactive intestinal peptide.
Topics: Adenocarcinoma; Brimonidine Tartrate; Cell Line; Clonidine; Colonic Neoplasms; Cyclic AMP; Epinephrine; Fructosediphosphates; Hexosediphosphates; Humans; Quinoxalines; Vasoactive Intestinal Peptide; Yohimbine | 1986 |