Page last updated: 2024-08-17

quinoxalines and Bladder Cancer

quinoxalines has been researched along with Bladder Cancer in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.57)29.6817
2010's4 (14.29)24.3611
2020's23 (82.14)2.80

Authors

AuthorsStudies
Claiborne, RT; Tsan, GL1
Avadhani, A; De Porre, P; Dosne, AG; Goeyvaerts, N; Li, LY; O'Hagan, A; Ouellet, D; Perez Ruixo, JJ; Valade, E1
Akapame, S; Burgess, EF; Duran, I; Fleming, MT; García-Donas, J; Huddart, RA; Joshi, M; Loriot, Y; Mellado, B; Monga, M; Necchi, A; O'Hagan, A; Park, SH; Rezazadeh Kalebasty, A; Santiago-Walker, AE; Siefker-Radtke, AO; Tagawa, ST; Varlamov, S; Zakharia, Y1
Loriot, Y; Siefker-Radtke, AO1
Hu, C; Hu, X; Shang, X; Zhao, Y; Zheng, T1
Cosmai, L; Franza, A; Giannatempo, P; Pirovano, M1
Belal, F; El-Enany, N; Elawady, T; Khedr, A1
Bellmunt, J; Montazeri, K1
Baur, EM; Gschwend, JE; Hindupur, SV; Holm, PS; Horn, T; Koch, JA; Nawroth, R; Schmid, SC; Slotta-Huspenina, J; Wang, D; Youssef, A1
Kolesar, JM; Myint, ZW; Roubal, K1
Lebenthal, J; Nauseef, JT; Tagawa, ST; Villamar, DM; Vlachostergios, PJ1
Carles, J; González, M; Maldonado, X; Mateo, J; Morales-Barrera, R; Morote, J; Raventos, C; Serra, E; Suárez, C; Valverde, C1
Galsky, MD; Patel, V; Qin, Q1
Amir, M; Javed, S; Qureshi, MA1
Ertl, IE; Ilijazi, D; Loriot, Y; Mostafaei, H; Shariat, SF1
Bagby, S; Bortoletti, C; D'Angelo, A; Galli, IC; Roviello, G1
Bednova, O; Leyton, JV1
Montazeri, K; Sonpavde, G1
Bansal, P; Dwivedi, DK; Goyal, S; Gupta, V; Hatwal, D; Maithani, M; Sharma, P1
Al-Obaidy, KI; Cheng, L1
Alberts, AR; Iflé, IG; Scholtes, MP; van der Veldt, AAM; Verhagen, PCMS; Zuiverloon, TCM1
Hubert, P; Loriot, Y; Selmani, Z; Thiery-Vuillemin, A1
Kim, HS; Seo, HK1
Alvarez, JD; Bahleda, R; Bell, K; Cardona, GM; Gaffney, D; Karkera, JD; King, P; Lorenzi, MV; Luo, FR; Moy, CH; Platero, SJ; Portale, JC; Santiago-Walker, A; Sharp, M1
Bétrian, S; Delord, JP; Gomez-Roca, C; Sibaud, V; Vigarios, E1
He, S; Li, X; Martin, DT; Tian, Y; Weiss, RM1
Bastaros, JM; Carles, J; de Castro, AM; Maldonado, X; Morales-Barrera, R; Morote, J; Racca, F; Suárez, C; Valverde, C1
Archer, CL; Haas, GP; Jones, RF; Morse, P; Shirai, T; Wang, CY1

Reviews

15 review(s) available for quinoxalines and Bladder Cancer

ArticleYear
Erdafitinib in locally advanced/metastatic urothelial carcinoma with certain
    Future oncology (London, England), 2022, Volume: 18, Issue:19

    Topics: Carcinoma, Transitional Cell; Humans; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Urinary Bladder Neoplasms

2022
Erdafitinib for the treatment of metastatic bladder cancer.
    Expert review of clinical pharmacology, 2020, Volume: 13, Issue:1

    Topics: Animals; Carcinoma, Transitional Cell; Humans; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Urinary Bladder Neoplasms

2020
Erdafitinib: A novel therapy for FGFR-mutated urothelial cancer.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, Feb-19, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Humans; Progression-Free Survival; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Urinary Bladder Neoplasms

2020
An evaluation of the efficacy and safety of erdafitinib for the treatment of bladder cancer.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:8

    Topics: Antineoplastic Agents; Clinical Trials, Phase II as Topic; Humans; Molecular Targeted Therapy; Pyrazoles; Quinoxalines; Receptors, Fibroblast Growth Factor; Treatment Outcome; Urinary Bladder Neoplasms

2020
The future of bladder cancer therapy: Optimizing the inhibition of the fibroblast growth factor receptor.
    Cancer treatment reviews, 2020, Volume: 86

    Topics: Antineoplastic Agents; Humans; Neoplasm Metastasis; Pyrazoles; Quinoxalines; Randomized Controlled Trials as Topic; Receptors, Fibroblast Growth Factor; Urinary Bladder Neoplasms

2020
Urothelial carcinoma: the development of FGFR inhibitors in combination with immune checkpoint inhibitors.
    Expert review of anticancer therapy, 2020, Volume: 20, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Drug Development; Humans; Immune Checkpoint Inhibitors; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 3; Signal Transduction; Urinary Bladder Neoplasms

2020
Fibroblast growth factor receptors across urothelial carcinoma landscape.
    Current opinion in urology, 2020, Volume: 30, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Humans; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Treatment Outcome; Urinary Bladder Neoplasms; Urologic Neoplasms

2020
Overview of the clinical use of erdafitinib as a treatment option for the metastatic urothelial carcinoma: where do we stand.
    Expert review of clinical pharmacology, 2020, Volume: 13, Issue:10

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Apoptosis; Carcinoma, Transitional Cell; Disease Progression; Humans; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Urinary Bladder Neoplasms

2020
Targeted Molecular Therapeutics for Bladder Cancer-A New Option beyond the Mixed Fortunes of Immune Checkpoint Inhibitors?
    International journal of molecular sciences, 2020, Oct-01, Volume: 21, Issue:19

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; B7-H1 Antigen; Camptothecin; Cell Adhesion Molecules; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Immunoconjugates; Immunotherapy; Lymphatic Metastasis; Molecular Targeted Therapy; Programmed Cell Death 1 Receptor; Pyrazoles; Quinoxalines; Urinary Bladder; Urinary Bladder Neoplasms

2020
Salvage systemic therapy for metastatic urothelial carcinoma: an unmet clinical need.
    Expert review of anticancer therapy, 2021, Volume: 21, Issue:3

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Carcinoma, Transitional Cell; Humans; Immune Checkpoint Inhibitors; Molecular Targeted Therapy; Neoplasm Metastasis; Pyrazoles; Quinoxalines; Salvage Therapy; Survival Rate; Urinary Bladder Neoplasms

2021
Erdafitinib as a Novel and Advanced Treatment Strategy of Metastatic Urothelial Carcinoma.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:18

    Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Pyrazoles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 3; Urinary Bladder Neoplasms

2021
Fibroblast growth factor receptor (
    Journal of clinical pathology, 2021, Volume: 74, Issue:8

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma; Exons; Gene Amplification; Gene Fusion; Genetic Predisposition to Disease; Humans; Molecular Targeted Therapy; Mutation, Missense; Phenotype; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 3; Thiophenes; Urinary Bladder Neoplasms; Urothelium

2021
Biomarker-Oriented Therapy in Bladder and Renal Cancer.
    International journal of molecular sciences, 2021, Mar-11, Volume: 22, Issue:6

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; B7-H1 Antigen; Biomarkers, Tumor; Carcinoma, Renal Cell; Cisplatin; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Kidney Neoplasms; Lymphatic Metastasis; Mutation; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Recurrence; Urinary Bladder Neoplasms

2021
Emerging treatments for bacillus Calmette-Guérin-unresponsive non-muscle-invasive bladder cancer.
    Investigative and clinical urology, 2021, Volume: 62, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Clinical Trials as Topic; Genes, Viral; Genetic Therapy; Humans; Hyperthermia; Immune Checkpoint Inhibitors; Immunoconjugates; Organ Sparing Treatments; Photochemotherapy; Pyrazoles; Quinoxalines; Retreatment; Treatment Failure; Urinary Bladder Neoplasms

2021
Targeting fibroblast growth factor receptors and immune checkpoint inhibitors for the treatment of advanced bladder cancer: New direction and New Hope.
    Cancer treatment reviews, 2016, Volume: 50

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Transitional Cell; Humans; Ipilimumab; Nivolumab; Phenylurea Compounds; Piperazines; Pyrazoles; Pyridines; Pyrimidines; Quinolines; Quinoxalines; Receptors, Fibroblast Growth Factor; Urinary Bladder Neoplasms

2016

Trials

2 trial(s) available for quinoxalines and Bladder Cancer

ArticleYear
Exposure-response analyses of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma.
    Cancer chemotherapy and pharmacology, 2022, Volume: 89, Issue:2

    Topics: Aged; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Progression-Free Survival; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Receptors, Fibroblast Growth Factor; Survival Rate; Urinary Bladder Neoplasms

2022
Efficacy and safety of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma: long-term follow-up of a phase 2 study.
    The Lancet. Oncology, 2022, Volume: 23, Issue:2

    Topics: Aged; Carcinoma, Transitional Cell; Central Serous Chorioretinopathy; ErbB Receptors; Follow-Up Studies; Humans; Middle Aged; Mutation; Neoplasm Metastasis; Pyrazoles; Quinoxalines; Urinary Bladder Neoplasms

2022

Other Studies

11 other study(ies) available for quinoxalines and Bladder Cancer

ArticleYear
Case Report: Erdafitinib-induced Central Serous Chorioretinopathy.
    Optometry and vision science : official publication of the American Academy of Optometry, 2022, 01-01, Volume: 99, Issue:1

    Topics: Aged, 80 and over; Carcinoma, Transitional Cell; Central Serous Chorioretinopathy; Female; Humans; Male; Protein Kinase Inhibitors; Pyrazoles; Quality of Life; Quinoxalines; Receptors, Fibroblast Growth Factor; United States; Urinary Bladder Neoplasms

2022
Erdafitinib for locally advanced or metastatic urothelial carcinoma.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2022, 05-24, Volume: 79, Issue:11

    Topics: Carcinoma, Transitional Cell; Humans; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Urinary Bladder Neoplasms

2022
Ipatasertib (GDC-0068) and erdafitinib co-treatment for inducing mitochondrial apoptosis through Bim upregulation in bladder cancer cells.
    Biochemical and biophysical research communications, 2022, 05-14, Volume: 604

    Topics: Apoptosis; Bcl-2-Like Protein 11; Humans; Mitochondria; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Quinoxalines; Receptors, Fibroblast Growth Factor; Up-Regulation; Urinary Bladder Neoplasms

2022
Utility of Kolliphor RH 40 in micellar sensitized fluorescence of the novel tyrosine kinase inhibitor "Erdafitinib": Application to human plasma.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, Oct-05, Volume: 278

    Topics: Carcinoma, Transitional Cell; Humans; Micelles; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Solvents; Spectrometry, Fluorescence; Urinary Bladder Neoplasms

2022
STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy.
    International journal of molecular sciences, 2020, Feb-07, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Combined Modality Therapy; Cyclic S-Oxides; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Humans; Hydroxybenzoates; Janus Kinases; Nitriles; Nitrofurans; Oncolytic Virotherapy; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Quinoxalines; STAT3 Transcription Factor; STAT6 Transcription Factor; Urinary Bladder Neoplasms

2020
Biomolecular interactions and binding dynamics of tyrosine kinase inhibitor erdafitinib, with human serum albumin.
    Journal of biomolecular structure & dynamics, 2021, Volume: 39, Issue:11

    Topics: Binding Sites; Carcinoma, Transitional Cell; Circular Dichroism; Humans; Molecular Docking Simulation; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Quinoxalines; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Tumor Microenvironment; Urinary Bladder Neoplasms

2021
FGFR alterations in urothelial carcinoma: Picking the right target.
    Bulletin du cancer, 2021, Volume: 108, Issue:6

    Topics: Carcinoma, Transitional Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Gene Fusion; Humans; Molecular Targeted Therapy; Morpholines; Mutation; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Thiophenes; Urinary Bladder Neoplasms

2021
Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:8

    Topics: Animals; Biomarkers, Tumor; Male; Oncogene Proteins, Fusion; Oncogenes; Pyrazoles; Quinoxalines; Rats, Nude; Receptors, Fibroblast Growth Factor; Tomography, X-Ray Computed; Urinary Bladder Neoplasms

2017
Severe Onycholysis and Eyelash Trichomegaly Following Use of New Selective Pan-FGFR Inhibitors.
    JAMA dermatology, 2017, 07-01, Volume: 153, Issue:7

    Topics: Eyelashes; Eyelid Diseases; Fibroblast Growth Factors; Glioblastoma; Humans; Male; Middle Aged; Onycholysis; Pyrazoles; Quinoxalines; Severity of Illness Index; Urinary Bladder Neoplasms

2017
Synergistic inhibition of GP130 and ERK signaling blocks chemoresistant bladder cancer cell growth.
    Cellular signalling, 2019, Volume: 63

    Topics: Butadienes; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Hydrazines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Nitriles; Quinoxalines; Urinary Bladder Neoplasms

2019
Carcinogenicity of the N-hydroxy derivative of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 2-amino-3, 8-dimethyl-imidazo[4,5-f]quinoxaline and 3, 2'-dimethyl-4-aminobiphenyl in the rat.
    Cancer letters, 2000, Jul-03, Volume: 155, Issue:1

    Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Body Weight; Carcinogens; Carcinoma, Transitional Cell; Colonic Neoplasms; Hyperplasia; Imidazoles; Male; Mutagens; Prostatic Neoplasms; Pyridines; Quinoxalines; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms

2000