Page last updated: 2024-08-17

quinoxalines and Allodynia

quinoxalines has been researched along with Allodynia in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (30.23)	18.2507
2000's	17 (39.53)	29.6817
2010's	13 (30.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, X; Feng, M; Liu, T; Wan, L; Yao, W; Zhang, B; Zhang, C; Zhang, Y	1
Gu, K; Jiang, B; Li, Y; Ma, P; Ma, X; Song, T; Wang, C; Yang, Y; Zhao, J	1
Ben Aissa, M; Bennett, BM; Bertels, Z; Gaisina, IN; Gandhi, R; Lee, SH; Litosh, V; Moye, LS; Novack, M; Pradhan, AA; Thatcher, GR; Tipton, AF; Wang, Y	1
Cervantes-Durán, C; Granados-Soto, V; Murbartián, J; Quiñonez-Bastidas, GN; Rocha-González, HI	1
Ahn, DK; Bae, YC; Kim, HJ; Kim, MJ; Kim, YJ; Lee, SY; Nam, SH; Yang, KY	1
Araldi, D; Ferrari, LF; Ferreira, SH; Lotufo, CM; Macedo, LP; Parada, CA; Rodrigues, MA	1
Bruchas, MR; Campos-Jurado, Y; Carlton, SM; Comer, SD; Gonzalez-Romero, J; Hipólito, L; Morón, JA; Virag, L; Walker, BM; Whittington, R; Wilson-Poe, A; Zhong, E	1
Jang, JH; Jun, J; Jung, SJ; Kim, DW; Leem, JW; Nam, TS	1
Deng, ZD; Feng, YC; Shen, HL; Zhu, H; Zhu, R	1
Martina, M; Pollema-Mays, SL; Radzicki, D; Sanz-Clemente, A	1
Cheevers, CV; Donello, JE; Gil, DW; Kedzie, KM; Manlapaz, CA; Rao, S; Tang, E	1
Côrtes, SF; Duarte, ID; Galdino, GS; Perez, AC; Resende, LC; Romero, TR; Silva, GC	1
Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Torres, JN; Vale, ML	1
Chen, S; Mohajerani, MH; Murphy, TH; Xie, Y	1
Ferreira, SH; Parada, CA; Vivancos, GG	1
Brennan, TJ; Niemeier, JS; Pogatzki, EM; Sorkin, LS	1
Cury, Y; Picolo, G	1
Bae, HB; Choi, JI; Yoon, MH	1
Caterina, M; Pogatzki-Zahn, EM; Raja, SN; Shimizu, I	1
Brennan, TJ; Niemeier, JS; Pogatzki-Zahn, EM; Sorkin, LS	1
Ignatowski, TA; Knight, PR; Spengler, RN; Sud, R	1
Capra, NF; Lee, J; Ro, JY; Zhang, Y	1
Chang, HM; Chen, GD; Chen, MJ; Lai, CY; Lee, SD; Lin, TB; Pan, SF; Peng, ML; Tung, KC; Wang, PY	1
Mao, J; Mayer, DJ; Price, DD	1
Borsini, F; Brambilla, A; Grippa, N; Prudentino, A	1
Hao, JX; Xu, XJ	1
Coutinho, SV; Gebhart, GF; Meller, ST	1
Chaplan, SR; Malmberg, AB; Yaksh, TL	1
Brennan, TJ; Umali, E; Zahn, PK	1
Aley, KO; Levine, JD; McCarter, G	1
Coutinho, VS; Gebhart, FG; Urban, OM	1
Cunha, FQ; Ferreira, SH; Teixeira, MM	1
Bennett, AD; Everhart, AW; Hulsebosch, CE	1
Duarte, ID; Ferreira, SH	1
Fuchs, PN; Meyer, RA; Raja, SN	1
Cunha, FQ; Prado, WA; Schiavon, VF	1
Randich, A; Turnbach, ME	1
Johns, RA; Tao, YX	1
King, EW; Skyba, DA; Sluka, KA	1
Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM	1
Hayes, RL; Lu, J; Mao, J; Mayer, DJ; Price, DD	1
Malmberg, AB; Yaksh, TL	1
Levine, JD; Taiwo, YO	1

Trials

1 trial(s) available for quinoxalines and Allodynia

Article	Year
Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. Pain, 2001, Feb-01, Volume: 90, Issue:1-2 Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analysis of Variance; Brimonidine Tartrate; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Nociceptors; Norepinephrine; Pain Threshold; Phenylephrine; Quinoxalines; Receptors, Adrenergic; Skin; Vasoconstrictor Agents	2001

Article

Year

Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin.

Pain, 2001, Feb-01, Volume: 90, Issue:1-2

Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analysis of Variance; Brimonidine Tartrate; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Nociceptors; Norepinephrine; Pain Threshold; Phenylephrine; Quinoxalines; Receptors, Adrenergic; Skin; Vasoconstrictor Agents

2001

Other Studies

42 other study(ies) available for quinoxalines and Allodynia

Article	Year
Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death. ACS chemical neuroscience, 2019, 12-18, Volume: 10, Issue:12 Topics: Animals; Cation Transport Proteins; Cyclooxygenase 2; Drug Tolerance; Ferroptosis; Gene Expression Regulation; Hyperalgesia; Inflammation; Iron; Iron Overload; Lipid Peroxidation; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitochondria; Morphine; Neurons; Nociception; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Quinoxalines; Random Allocation; Reactive Oxygen Species; Receptors, Transferrin; Spinal Cord; Spiro Compounds; Superoxide Dismutase	2019
Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain. Journal of neuroscience research, 2018, Volume: 96, Issue:2 Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalidomide; Valine	2018
Soluble guanylyl cyclase is a critical regulator of migraine-associated pain. Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:8 Topics: Adrenergic beta-Antagonists; Allosteric Regulation; Animals; Anticonvulsants; Calcitonin Gene-Related Peptide; Disease Models, Animal; Enzyme Inhibitors; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Migraine Disorders; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Oxadiazoles; Propranolol; Proto-Oncogene Proteins c-fos; Quinoxalines; Serotonin 5-HT1 Receptor Agonists; Soluble Guanylyl Cyclase; Sumatriptan; Topiramate	2018
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats. Life sciences, 2013, Oct-17, Volume: 93, Issue:17 Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glyburide; Hyperalgesia; Indazoles; Methiothepin; Naloxone; NG-Nitroarginine Methyl Ester; Oxadiazoles; Pain Measurement; Piperazines; Piperidones; Pyridines; Quinoxalines; Rats; Spiro Compounds	2013
Differential regulation of peripheral IL-1β-induced mechanical allodynia and thermal hyperalgesia in rats. Pain, 2014, Volume: 155, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Interleukin-1beta; Male; Nerve Tissue Proteins; Pain Threshold; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion	2014
Inflammatory sensitization of nociceptors depends on activation of NMDA receptors in DRG satellite cells. Proceedings of the National Academy of Sciences of the United States of America, 2014, Dec-23, Volume: 111, Issue:51 Topics: 2-Amino-5-phosphonovalerate; Animals; Dinoprostone; Ganglia, Spinal; Hyperalgesia; Nociceptors; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Satellite Cells, Perineuronal	2014
Inflammatory Pain Promotes Increased Opioid Self-Administration: Role of Dysregulated Ventral Tegmental Area μ Opioid Receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Sep-02, Volume: 35, Issue:35 Topics: Action Potentials; Analgesics, Opioid; Animals; Conditioning, Operant; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glycine Agents; Heroin; Hyperalgesia; Inflammation; Inhibitory Postsynaptic Potentials; Male; Neurons; Pain; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Strychnine; Sucrose; Ventral Tegmental Area	2015
Peripheral NMDA Receptors Mediate Antidromic Nerve Stimulation-Induced Tactile Hypersensitivity in the Rat. Mediators of inflammation, 2015, Volume: 2015 Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dizocilpine Maleate; Electric Stimulation; Glutamic Acid; Hyperalgesia; Isoquinolines; Male; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Tibial Nerve	2015
[Analgesic effects of ionotropic glutamate receptor antagonists MK-801 and NBQX on collagen-induced arthritis rats]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2016, 12-18, Volume: 48, Issue:6 Topics: Analgesics; Animals; Arthritis, Experimental; Cyclooxygenase 2; Dizocilpine Maleate; Edema; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Janus Kinase 3; Male; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate	2016
Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 03-01, Volume: 37, Issue:9 Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sciatica; Subcellular Fractions; Synaptic Transmission; Valine	2017
Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesia. Anesthesiology, 2009, Volume: 110, Issue:2 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Brimonidine Tartrate; Calcium; Clonidine; Dinoprostone; Drug Interactions; Excitatory Amino Acid Agonists; Exploratory Behavior; Hyperalgesia; Injections, Spinal; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain Measurement; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2	2009
Ketamine activates the L-arginine/Nitric oxide/cyclic guanosine monophosphate pathway to induce peripheral antinociception in rats. Anesthesia and analgesia, 2011, Volume: 113, Issue:5 Topics: Analgesia; Anesthetics, Dissociative; Animals; Arginine; Cyclic AMP; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hyperalgesia; Ketamine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Pain; Peripheral Nervous System Diseases; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction	2011
Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2012, Volume: 45, Issue:6 Topics: Analgesics; Animals; Arginine; Carcinoma 256, Walker; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; KATP Channels; Male; Nitric Oxide; Nociception; Oxadiazoles; Pain Measurement; Pain Threshold; Quinoxalines; Rats; Rats, Wistar; Signal Transduction	2012
Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Sep-26, Volume: 32, Issue:39 Topics: Anesthetics, Local; Animals; Bacterial Proteins; Carrier Proteins; Channelrhodopsins; Disease Models, Animal; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Forelimb; Hyperalgesia; In Vitro Techniques; Ischemia; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Optogenetics; Physical Stimulation; Quinoxalines; Reperfusion Injury; Tetrodotoxin; Valine	2012
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues. British journal of pharmacology, 2003, Volume: 138, Issue:7 Topics: Animals; Arginine; Bucladesine; Cyclic GMP; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Subcutaneous; Male; Molsidomine; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Subcutaneous Tissue; Time Factors	2003
Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision. Pain, 2003, Volume: 105, Issue:1-2 Topics: Animals; Behavior, Animal; Diagnosis, Differential; Excitatory Amino Acid Antagonists; Foot; Hyperalgesia; Male; Muscle, Skeletal; Neurotoxins; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord	2003
Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist. Life sciences, 2004, Jun-18, Volume: 75, Issue:5 Topics: Analgesics; Animals; Crotalid Venoms; Crotalus; Dinoprostone; Drug Antagonism; Enzyme Inhibitors; Hyperalgesia; Indazoles; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa	2004
Antinociceptive interactions between intrathecal gabapentin and MK801 or NBQX in rat formalin test. Journal of Korean medical science, 2005, Volume: 20, Issue:2 Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	2005
Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain. Pain, 2005, Volume: 115, Issue:3 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hot Temperature; Hyperalgesia; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Nociceptors; Pain, Postoperative; Physical Stimulation; Proto-Oncogene Proteins c-fos; Quinoxalines; Skin; TRPV Cation Channels	2005
[Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision]. Schmerz (Berlin, Germany), 2006, Volume: 20, Issue:3 Topics: Animals; Calcium; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Mechanoreceptors; Muscle, Skeletal; Neurotoxins; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord	2006
Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of norepinephrine release. Neuropharmacology, 2007, Volume: 52, Issue:2 Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Radiation; Electric Stimulation; Functional Laterality; Hippocampus; Hyperalgesia; In Situ Hybridization; In Vitro Techniques; Locus Coeruleus; Male; Norepinephrine; Pain Measurement; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sciatica; Tumor Necrosis Factor-alpha	2007
Role of soluble guanylate cyclase in the trigeminal subnucleus caudalis in capsaicin-induced muscle hypersensitivity. Brain research, 2007, Dec-12, Volume: 1184 Topics: Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hyperalgesia; Male; Masseter Muscle; Methylene Blue; Mice; Nerve Tissue Proteins; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sensory Thresholds; Soluble Guanylyl Cyclase; Time Factors; Trigeminal Caudal Nucleus	2007
Calcium/calmodulin-dependent kinase II mediates NO-elicited PKG activation to participate in spinal reflex potentiation in anesthetized rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2 Topics: Action Potentials; Anesthesia; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic GMP-Dependent Protein Kinases; Electromyography; Enzyme Inhibitors; Hyperalgesia; Neuronal Plasticity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Reflex; Signal Transduction; Spinal Cord	2008
Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; G(M1) Ganglioside; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Morphine; Pain; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate	1994
Pharmacological characterization of AMPA-induced biting behaviour in mice. European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate	1996
Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered excitatory amino acid receptor antagonists. Pain, 1996, Volume: 66, Issue:2-3 Topics: Animals; Behavior, Animal; Chronic Disease; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Hyperalgesia; Ischemia; Motor Activity; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries	1996
Intracolonic zymosan produces visceral hyperalgesia in the rat that is mediated by spinal NMDA and non-NMDA receptors. Brain research, 1996, Oct-14, Volume: 736, Issue:1-2 Topics: Animals; Colon; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Zymosan	1996
Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Formaldehyde; Hyperalgesia; Injections, Spinal; Ketamine; Male; Memantine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerves; Touch	1997
Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain. Pain, 1998, Volume: 74, Issue:2-3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Nociceptors; Pain, Postoperative; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Metabotropic Glutamate; Spinal Cord	1998
Nitric oxide signaling in pain and nociceptor sensitization in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-01, Volume: 18, Issue:17 Topics: Animals; Dinoprostone; Enzyme Inhibitors; Guanylate Cyclase; Hyperalgesia; Male; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Signal Transduction; Tetrodotoxin	1998
Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia. Pain, 1998, Volume: 78, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Colon; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Immunohistochemistry; Male; Medulla Oblongata; Microinjections; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Viscera; Zymosan	1998
Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. British journal of pharmacology, 1999, Volume: 127, Issue:3 Topics: Animals; Bradykinin; Carrageenan; Cyclic AMP; Cyclic GMP; Dinoprostone; Dopamine; Hyperalgesia; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; Isoquinolines; Male; Oxadiazoles; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Rolipram; Second Messenger Systems; Sulfonamides; Tumor Necrosis Factor-alpha	1999
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury. Brain research, 2000, Mar-17, Volume: 859, Issue:1 Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine	2000
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway. Mediators of inflammation, 2000, Volume: 9, Issue:1 Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction	2000
Dual effect of local application of nitric oxide donors in a model of incision pain in rats. European journal of pharmacology, 2002, Apr-19, Volume: 441, Issue:1-2 Topics: Animals; Disease Models, Animal; Diuretics, Osmotic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hindlimb; Hyperalgesia; Isosorbide; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Donors; Nitrites; Ointments; Oxadiazoles; Pain Threshold; Pain, Postoperative; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Time Factors	2002
The role of spinal neurokinin-1 and glutamate receptors in hyperalgesia and allodynia induced by prostaglandin E(2) or zymosan in the rat. Pain, 2002, Volume: 97, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Dinoprostone; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Quinoxalines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Zymosan	2002
Activation and up-regulation of spinal cord nitric oxide receptor, soluble guanylate cyclase, after formalin injection into the rat hind paw. Neuroscience, 2002, Volume: 112, Issue:2 Topics: Animals; Behavior, Animal; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Guanylate Cyclase; Hindlimb; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Injections, Spinal; Male; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Pain Measurement; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Soluble Guanylyl Cyclase; Spinal Cord; Tissue Distribution; Up-Regulation	2002
Effects of NMDA and non-NMDA ionotropic glutamate receptor antagonists on the development and maintenance of hyperalgesia induced by repeated intramuscular injection of acidic saline. Pain, 2002, Volume: 98, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Acids; Animals; Drug Administration Schedule; Drug Combinations; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Intramuscular; Male; Motor Activity; Muscle, Skeletal; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Sodium Chloride	2002
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats. European journal of pharmacology, 1992, Aug-25, Volume: 219, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine	1992
Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain research, 1992, Dec-11, Volume: 598, Issue:1-2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Pain; Peripheral Nervous System Diseases; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve	1992
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science (New York, N.Y.), 1992, Aug-28, Volume: 257, Issue:5074 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P	1992
Serotonin is a directly-acting hyperalgesic agent in the rat. Neuroscience, 1992, Volume: 48, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Hydroxyurea; Hyperalgesia; Indomethacin; Male; Nociceptors; Oxidopamine; Pain; Quinoxalines; Rats; Rats, Inbred Strains; Reflex; Sensory Thresholds; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1992