quinoxalines has been researched along with Ache in 78 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 32 (41.03) | 18.2507 |
2000's | 36 (46.15) | 29.6817 |
2010's | 10 (12.82) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Edwards, CM; Edwards, JR; Gooding, S; Javaid, MK; Leung, SK; Lwin, ST; Nador, G; Olechnowicz, SWZ; Ramasamy, K; Rao, SR; Weivoda, MM | 1 |
Balbaba, M; Çelebi, S; Ulaş, F | 1 |
Bonnet, CS; Evans, BA; Gilbert, SJ; Harvey, AK; Mason, DJ; Williams, AS | 1 |
Levitt, JO; Routt, ET | 1 |
Bruchas, MR; Campos-Jurado, Y; Carlton, SM; Comer, SD; Gonzalez-Romero, J; Hipólito, L; Morón, JA; Virag, L; Walker, BM; Whittington, R; Wilson-Poe, A; Zhong, E | 1 |
Deng, ZD; Feng, YC; Shen, HL; Zhu, H; Zhu, R | 1 |
Cunha, FQ; Duarte, DB; Ferrari, LF; Ferreira, SH; Funez, MI; Lorenzetti, BB; Parada, CA; Sachs, D | 1 |
Bauer, I; Freynhagen, R; Hermanns, H; Kollosche, K; Lipfert, P; Muth-Selbach, U; Stegmann, JU | 1 |
Clemente-Napimoga, JT; Ferreira, VH; Napimoga, MH; Parada, CA; Pellegrini-da-Silva, A; Tambeli, CH | 1 |
Abu-Hashem, AA; Badria, FA; Gouda, MA | 1 |
Côrtes, SF; Duarte, ID; Galdino, GS; Perez, AC; Resende, LC; Romero, TR; Silva, GC | 1 |
AlSharari, SD; Carroll, FI; Damaj, MI; McIntosh, JM | 1 |
Fischer, L; Menescal-de-Oliveira, L; Monaliza, SL; Parada, CA; Tambeli, CH | 1 |
Arendt-Nielsen, L; Sumikura, H | 1 |
Jia, H; Tang, JS; Xie, YF | 1 |
Han, HC; Hong, SK; Lee, KS; Min, SS; Park, JY; Yoon, YW; Zhang, GH | 1 |
Déciga-Campos, M; López-Muñoz, FJ | 1 |
Hamanaka, N; Ito, S; Matsumura, S; Minami, T; Nishizawa, M; Sasaguri, Y | 1 |
Li, W; Neugebauer, V | 1 |
Blackburn-Munro, G; Bomholt, SF; Erichsen, HK | 1 |
Ambriz-Tututi, M; Granados-Soto, V; Urquiza-Marín, H; Velázquez-Zamora, DA | 1 |
Castañeda-Hernández, G; Granados-Soto, V; Lozano-Cuenca, J | 1 |
Kamei, J; Saitoh, A; Tamura, N | 1 |
Granados-Soto, V; Torres-López, JE | 1 |
Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
An, TH; Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
Araiza-Saldaña, CI; Bermúdez-Ocaña, DY; Granados-Soto, V; Pérez-Severiano, F; Reyes-García, G | 1 |
Flores-Murrieta, FJ; Granados-Soto, V; Mixcoatl-Zecuatl, T | 1 |
Yonehara, N; Yoshimura, M | 1 |
Brito, GA; Cunha, FQ; Ferreira, SH; Lotufo, CM; Ribeiro, RA; Sachs, D; Vale, ML | 1 |
Gheitasi, IP; Haghparast, A; Lashgari, R | 1 |
Barr, GA; King, TE | 1 |
Cavalcante, IF; Ribeiro, RA; Rolim, DE; Souza, MH; Vale, ML | 1 |
Cao, Z; Chen, S; Fan, J; Li, Y; Owyang, C; Wu, X; Zhang, R | 1 |
Nishiyama, T | 2 |
Jedema, HP; Moghaddam, B | 1 |
Lücke, T; Neugebauer, V; Schaible, HG | 1 |
Dykstra, CL; Gebhart, GF; Meller, ST | 1 |
Reid, A; Sawynok, J | 1 |
Mao, J; Mayer, DJ; Price, DD | 1 |
Grubb, B; Lücke, T; Neugebauer, V; Schaible, HG | 1 |
Gebhart, GF; Kolhekar, R | 1 |
Bervoets, K; Gobert, A; Le Marouille-Girardon, S; Millan, MJ; Renouard, A; Rivet, JM; Widdowson, P | 1 |
Goettl, VM; Larson, AA | 1 |
Kulakova, AV; Meerson, FZ; Saltykova, VA | 1 |
Hao, JX; Seiger, A; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
Keana, JF; Kest, B; Liebeskind, JC; Marek, P; Vaccarino, AL; Weber, E | 1 |
Loomis, CW; Sherman, SE | 1 |
Lutfy, K; Weber, E | 1 |
Chaplan, SR; Malmberg, AB; Yaksh, TL | 1 |
Mamede Rosa, ML; Prado, WA | 1 |
Calcutt, NA; Chaplan, SR | 1 |
Hole, K; Svendsen, F; Tjølsen, A | 1 |
Aley, KO; Levine, JD; McCarter, G | 1 |
Tao, YX; Zhao, ZQ | 1 |
Gyermek, L; Kawasaki-Yatsugi, S; Lee, C; Nishiyama, T; Yamaguchi, T | 2 |
Song, XJ; Zhao, ZQ | 1 |
Chen, J; Li, H; Li, Z; Luo, C; Zheng, J | 1 |
Kawamata, T; Omote, K | 1 |
Doan, P; Lutfy, K; Nguyen, M; Weber, E | 1 |
Bennett, AD; Everhart, AW; Hulsebosch, CE | 1 |
Aguirre-Bañuelos, P; Granados-Soto, V | 1 |
Pollard, M | 1 |
Gyermek, L; Hanaoka, K; Kawasaki-Yatsugi, S; Lee, C; Nishiyama, T; Yamaguchi, T | 1 |
Gao, X; Wu, G; Yang, Z; Zhang, Y | 1 |
Shu, YS; Zhao, ZQ | 1 |
Abraham, KE; Brewer, KL; McGinty, JF | 1 |
Granados-Soto, V; Lázaro-Ibáñez, GG; Torres-López, JE | 1 |
Hu, JY; Zhao, ZQ | 1 |
Afrah, AW; Brodin, E; Gustafsson, H; Olgart, L; Stiller, CO | 1 |
Ahmadi, MA; Anderlini, P; Esmaeli, B; Kim, RY; Naderi, AA; Rivera, P | 1 |
Hayes, RL; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
Levine, JD; Taiwo, YO | 1 |
Lund, A; Olsen, UB | 1 |
Coderre, TJ; Melzack, R | 1 |
Eaton, SA; Salt, TE | 1 |
1 trial(s) available for quinoxalines and Ache
Article | Year |
---|---|
Effect of prophylactic intraocular pressure-lowering medication on pain during cataract surgery.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cataract; Cloprostenol; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Phacoemulsification; Postoperative Period; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost | 2013 |
77 other study(ies) available for quinoxalines and Ache
Article | Year |
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Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment.
Topics: Adiponectin; Animals; Bone Marrow; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mice; Multiple Myeloma; Nerve Growth Factor; Neuroglia; NF-kappa B; Osteoblasts; Pain; Peptides; Piperidines; Quinoxalines; Stromal Cells; Tumor Microenvironment; Tumor Necrosis Factor-alpha | 2019 |
AMPA/kainate glutamate receptors contribute to inflammation, degeneration and pain related behaviour in inflammatory stages of arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Behavior, Animal; Cartilage, Articular; Excitatory Amino Acid Antagonists; Humans; Immunohistochemistry; Inflammation; Interleukin-6; Knee Joint; Male; Menisci, Tibial; Osteoarthritis; Osteoblasts; Pain; Quinoxalines; Radiography; Rats; Receptors, AMPA; Receptors, Kainic Acid; Synovial Membrane | 2015 |
Rebound erythema and burning sensation from a new topical brimonidine tartrate gel 0.33%.
Topics: Administration, Cutaneous; Adult; Brimonidine Tartrate; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythema; Female; Follow-Up Studies; Gels; Humans; Pain; Quinoxalines; Recurrence; Risk Assessment; Rosacea; Sampling Studies; Severity of Illness Index | 2014 |
Inflammatory Pain Promotes Increased Opioid Self-Administration: Role of Dysregulated Ventral Tegmental Area μ Opioid Receptors.
Topics: Action Potentials; Analgesics, Opioid; Animals; Conditioning, Operant; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glycine Agents; Heroin; Hyperalgesia; Inflammation; Inhibitory Postsynaptic Potentials; Male; Neurons; Pain; Pain Threshold; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Strychnine; Sucrose; Ventral Tegmental Area | 2015 |
[Analgesic effects of ionotropic glutamate receptor antagonists MK-801 and NBQX on collagen-induced arthritis rats].
Topics: Analgesics; Animals; Arthritis, Experimental; Cyclooxygenase 2; Dizocilpine Maleate; Edema; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hyperalgesia; Janus Kinase 3; Male; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Dopamine; Drug Interactions; Enzyme Inhibitors; Indomethacin; Interleukin-1beta; Male; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Sensory Receptor Cells; Signal Transduction | 2008 |
Antinociceptive effects of systemic lidocaine: involvement of the spinal glycinergic system.
Topics: Analgesics; Animals; Binding Sites; Glycine; Glycine Agents; Lidocaine; Organophosphonates; Pain; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Substrate Specificity; Synaptic Transmission | 2009 |
Gonadal hormones decrease temporomandibular joint kappa-mediated antinociception through a down-regulation in the expression of kappa opioid receptors in the trigeminal ganglia.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Down-Regulation; Female; Gonadal Hormones; Humans; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Sex Characteristics; Signal Transduction; Temporomandibular Joint; Trigeminal Ganglion | 2009 |
Synthesis of some new pyrimido[2',1':2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Evaluation, Preclinical; Edema; Female; Male; Mice; Molecular Structure; Pain; Pain Measurement; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles | 2010 |
Ketamine activates the L-arginine/Nitric oxide/cyclic guanosine monophosphate pathway to induce peripheral antinociception in rats.
Topics: Analgesia; Anesthetics, Dissociative; Animals; Arginine; Cyclic AMP; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hyperalgesia; Ketamine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Pain; Peripheral Nervous System Diseases; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2011 |
The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models.
Topics: Analgesics; Animals; Azetidines; Benzazepines; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Motor Activity; Nicotinic Agonists; Pain; Pain Measurement; Pyridines; Quinoxalines; Receptors, Nicotinic; Varenicline | 2012 |
The functional role of ascending nociceptive control in defensive behavior.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Immobility Response, Tonic; Male; Motor Activity; Neural Pathways; Nociception; Nucleus Accumbens; Pain; Quinoxalines; Rats; Rats, Wistar; Somatostatin | 2012 |
MAC reduction after intrathecal coadministration of GABA(A) agonist and glutamate antagonist in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Agonists; Imidazoles; Injections, Spinal; Male; Methyl Ethers; Muscimol; N-Methylaspartate; Pain; Pulmonary Alveoli; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sevoflurane | 2003 |
The roles of different types of glutamate receptors involved in the mediation of nucleus submedius (Sm) glutamate-evoked antinociception in the rat.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microinjections; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus | 2003 |
The glutamatergic N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the joint contribute to the induction, but not maintenance, of arthritic pain in rats.
Topics: Animals; Arthritis, Experimental; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Joints; Male; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoenzymes; Lactones; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Sulfones; Uric Acid | 2003 |
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basidiomycota; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Heterocyclic Compounds; Indoles; Injections, Spinal; Japan; Kainic Acid; Lumbosacral Region; Male; Mice; Mice, Inbred Strains; Mushroom Poisoning; Oximes; Pain; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Time Factors | 2004 |
Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdala neurons in a model of arthritic pain.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Analysis of Variance; Animals; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kaolin; Male; Neural Inhibition; Neurons; Nociceptors; Pain; Pain Measurement; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Male; Morphine; Narcotics; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Kainic Acid; Tetrahydroisoquinolines; Time Factors | 2004 |
Analysis of the mechanism underlying the peripheral antinociceptive action of sildenafil in the formalin test.
Topics: Analgesics; Animals; Apamin; Charybdotoxin; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Injections, Subcutaneous; Oxadiazoles; Pain; Pain Measurement; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Tetraethylammonium; Time Factors; Tolbutamide | 2005 |
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Guanylate Cyclase; Hindlimb; Injections, Spinal; Injections, Subcutaneous; Methiothepin; Naloxone; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organic Chemicals; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Scorpion Venoms | 2005 |
Possible involvement of the spinal nitric oxide/cGMP pathway in vincristine-induced painful neuropathy in mice.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Injections, Spinal; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Reaction Time; Spinal Cord; Time Factors; Vincristine | 2005 |
Peripheral participation of the phosphodiesterase 3 on formalin-evoked nociception.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Injections, Subcutaneous; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors | 2005 |
Lack of the nitric oxide-cyclic GMP-potassium channel pathway for the antinociceptive effect of intrathecal zaprinast in a rat formalin test.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analgesics; Animals; Cyclic GMP; Formaldehyde; Glyburide; Injections, Spinal; Male; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Potassium Channels; Purinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Effect of diabetes on the mechanisms of intrathecal antinociception of sildenafil in rats.
Topics: Analgesia; Animals; Blood Glucose; Body Weight; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Sildenafil Citrate; Streptozocin; Sulfones; Time Factors | 2005 |
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.
Topics: Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Diazoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indazoles; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Okadaic Acid; Oxadiazoles; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Spinal Nerves; Stereoisomerism; Time Factors; Vasodilator Agents | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
Topics: Adenosine Triphosphate; Analgesia; Analgesics; Animals; Arginine; Bucladesine; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Ganglia, Spinal; Glyburide; Indoles; KATP Channels; Male; Neurons; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Pain; Pain Measurement; Pertussis Toxin; Potassium Channels, Inwardly Rectifying; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tolbutamide | 2006 |
Involvement of glutamatergic receptors in the nucleus cuneiformis in modulating morphine-induced antinociception in rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Nociceptors; Pain; Quinoxalines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 2007 |
Spinal cord ionotropic glutamate receptors function in formalin-induced nociception in preweaning rats.
Topics: Age Factors; Animals; Animals, Suckling; Behavior, Animal; Dizocilpine Maleate; Imidazoles; Motor Activity; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2007 |
Role of NO/cGMP/KATP pathway in antinociceptive effect of sildenafil in zymosan writhing response in mice.
Topics: Analgesics; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Pain; Piperazines; Potassium Channels; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones; Zymosan | 2007 |
Anterior cingulate cortex modulates visceral pain as measured by visceromotor responses in viscerally hypersensitive rats.
Topics: Albumins; Anaphylaxis; Animals; Colon; Disease Models, Animal; Electric Stimulation; Glutamic Acid; Gyrus Cinguli; Hypersensitivity; Male; Motor Cortex; Neurons; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Viscera | 2008 |
Interaction between a NMDA receptor antagonist, AP-5 and an AMPA receptor antagonist, YM 872 in antinociception in the spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Acute Disease; Analgesics; Animals; Chronic Disease; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Imidazoles; Male; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2008 |
Glutamatergic control of dopamine release during stress in the rat prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Pain; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 1994 |
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Ketamine; Male; Neurons; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Spinal Cord | 1993 |
Spinal supersensitivity to 5-HT1, 5-HT2 and 5-HT3 receptor agonists following 5,7-dihydroxytryptamine.
Topics: 5,7-Dihydroxytryptamine; Amphetamines; Analgesia; Analgesics; Analysis of Variance; Animals; Binding Sites; Indoles; Injections, Spinal; Male; Pain; Piperazines; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Up-Regulation | 1994 |
Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; G(M1) Ganglioside; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Morphine; Pain; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
The involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Ankle Joint; Arthritis, Experimental; Chronic Disease; Electrophysiology; Ketamine; Male; Neurons; Pain; Pressure; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
NMDA and quisqualate modulation of visceral nociception in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Colon; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Rectum | 1994 |
Multiple alpha-2 adrenergic receptor subtypes. II. Evidence for a role of rat R alpha-2A adrenergic receptors in the control of nociception, motor behavior and hippocampal synthesis of noradrenaline.
Topics: Animals; Brimonidine Tartrate; Hippocampus; Male; Motor Activity; Norepinephrine; Pain; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 1994 |
Antinociception induced by 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid (CPP), an N-methyl-D-aspartate (NMDA) competitive antagonist, plus 6,7-dinitroquinoxaline-2,3-dione (DNQX), a non-NMDA antagonist, differs from that induced by MK-801 pl
Topics: Animals; Dizocilpine Maleate; Formaldehyde; Injections, Spinal; Male; Mice; Pain; Pain Measurement; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1994 |
[The antimutagenic effect of adaptation to stress].
Topics: Adaptation, Physiological; Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Hematopoietic Stem Cells; Hypoxia; Male; Mice; Mice, Inbred C57BL; Mutagenesis; Mutagens; Pain; Periodicity; Quinoxalines; Stress, Physiological | 1993 |
Systemic excitatory amino acid receptor antagonists of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and of the N-methyl-D-aspartate (NMDA) receptor relieve mechanical hypersensitivity after transient spinal cord ischemia in
Topics: Animals; Dizocilpine Maleate; Female; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Skin Physiological Phenomena; Spinal Cord; Vocalization, Animal | 1993 |
NMDA receptor antagonists, MK-801 and ACEA-1011, prevent the development of tonic pain following subcutaneous formalin.
Topics: Analgesics; Animals; Behavior, Animal; Dizocilpine Maleate; Foot; Formaldehyde; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Pain; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1993 |
Strychnine-sensitive modulation is selective for non-noxious somatosensory input in the spinal cord of the rat.
Topics: Anesthesia, General; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Nerve Fibers; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine | 1996 |
Attenuation of nociceptive responses by ACEA-1021, a competitive NMDA receptor/glycine site antagonist, in the mice.
Topics: Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Microinjections; Pain; Pain Measurement; Quinoxalines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1996 |
Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Formaldehyde; Hyperalgesia; Injections, Spinal; Ketamine; Male; Memantine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerves; Touch | 1997 |
Antinociception induced by opioid or 5-HT agonists microinjected into the anterior pretectal nucleus of the rat.
Topics: Analgesics; Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Microinjections; Pain; Phenazocine; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Serotonin Receptor Agonists | 1997 |
Spinal pharmacology of tactile allodynia in diabetic rats.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Imidazoles; Injections, Spinal; Medetomidine; Morphine; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin | 1997 |
AMPA and NMDA receptor-dependent spinal LTP after nociceptive tetanic stimulation.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Muscle Contraction; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1998 |
Nitric oxide signaling in pain and nociceptor sensitization in the rat.
Topics: Animals; Dinoprostone; Enzyme Inhibitors; Guanylate Cyclase; Hyperalgesia; Male; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Signal Transduction; Tetrodotoxin | 1998 |
NMDA receptors mediating Fos expression in rat spinal cord induced by subcutaneous injection of formalin.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Neurons; Nociceptors; Pain; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1998 |
Analgesic interaction between intrathecal midazolam and glutamate receptor antagonists on thermal-induced pain in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; GABA Modulators; Imidazoles; Injections, Spinal; Midazolam; Motor Activity; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1999 |
Involvement of NMDA and non-NMDA receptors in transmission of spinal visceral nociception in cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cats; Excitatory Amino Acid Agonists; Female; Kainic Acid; Male; N-Methylaspartate; Nociceptors; Pain; Quinoxalines; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Splanchnic Nerves; Viscera | 1999 |
Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bee Venoms; Cats; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Injections, Subcutaneous; Male; N-Methylaspartate; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1999 |
Activation of spinal N-methyl-D-aspartate receptors stimulates a nitric oxide/cyclic guanosine 3,5-monophosphate/glutamate release cascade in nociceptive signaling.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanylate Cyclase; Male; Microdialysis; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Synaptic Transmission | 1999 |
The systemically administered competitive AMPA receptor antagonist, YM872, has analgesic effects on thermal or formalin-induced pain in rats.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Binding, Competitive; Formaldehyde; Hot Temperature; Imidazoles; Injections, Intraperitoneal; Male; Motor Activity; Nociceptors; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA | 1999 |
Effects of ACEA-1328, a NMDA receptor/glycine site antagonist, on U50,488H-induced antinociception and tolerance.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Glycine; Male; Mice; Nociceptors; Pain; Pain Measurement; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1999 |
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine | 2000 |
Evidence for the participation of the nitric oxide-cyclic GMP pathway in the antinociceptive action of meloxicam in the formalin test.
Topics: Analgesics, Non-Narcotic; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Guanylate Cyclase; Meloxicam; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Thiazines; Thiazoles | 2000 |
Ionotropic glutamate receptor-mediated responses in the rat primary somatosensory cortex evoked by noxious and innocuous cutaneous stimulation in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Hot Temperature; Male; N-Methylaspartate; Neurons; Pain; Piperazines; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Skin; Somatosensory Cortex; Synapses; Time Factors | 2000 |
Interaction between intrathecal morphine and glutamate receptor antagonists in formalin test.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; Morphine; Motor Activity; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Imidazoles; Injections, Spinal; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
The role of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors in modulating spinal nociceptive transmission in normal and carrageenan-injected rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carrageenan; Electric Stimulation; Electrophysiology; Female; Male; Neurons, Afferent; Nociceptors; Pain; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission | 2001 |
[Comparison of NMDA and non-NMDA receptor antagonists-induced inhibition in hindpaw withdrawal response to noxious thermal stimulation].
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Hindlimb; Hot Temperature; Male; Nociceptors; Pain; Pain Threshold; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin | 1998 |
The role of kainic acid/AMPA and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury.
Topics: Animals; Behavior, Animal; Dynorphins; Enkephalins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Grooming; Indans; Male; Nerve Degeneration; Neurons; Neurotoxins; Opioid Peptides; Pain; Pain Measurement; Protein Precursors; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; RNA, Messenger; Spinal Cord; Spinal Cord Injuries | 2001 |
Participation of the nitric oxide-cyclic GMP-ATP-sensitive K(+) channel pathway in the antinociceptive action of ketorolac.
Topics: Adenosine Triphosphate; Analgesics; Animals; Behavior, Animal; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glyburide; Guanylate Cyclase; Ketorolac; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Pain Measurement; Penicillamine; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2001 |
Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat.
Topics: Afferent Pathways; Animals; Cell Count; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin; Synaptic Transmission; Turpentine; Valine | 2001 |
Involvement of spinal N-methyl-D-aspartate receptors in capsaicin-induced in vivo release of substance P in the rat dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Capsaicin; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; Nerve Fibers; Nociceptors; Pain; Posterior Horn Cells; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P; Synapses; Synaptic Transmission | 2001 |
Scleritis as the initial clinical manifestation of graft-versus-host disease after allogenic bone marrow transplantation.
Topics: Acetazolamide; Bone Marrow Transplantation; Brimonidine Tartrate; Choroid Diseases; Drug Therapy, Combination; Graft vs Host Disease; Humans; Lymphoma, T-Cell; Male; Methylprednisolone; Middle Aged; Pain; Quinoxalines; Scleritis; Transplantation, Homologous | 2002 |
Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Pain; Peripheral Nervous System Diseases; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve | 1992 |
Serotonin is a directly-acting hyperalgesic agent in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Hydroxyurea; Hyperalgesia; Indomethacin; Male; Nociceptors; Oxidopamine; Pain; Quinoxalines; Rats; Rats, Inbred Strains; Reflex; Sensory Thresholds; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Inhibition by glutamate antagonists, MK-801 and NBQX, of cutaneo-cardiovascular pain reflex in rats.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dizocilpine Maleate; Female; Heart Rate; Pain; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Reflex; Skin; Skin Physiological Phenomena | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
Thalamic NMDA receptors and nociceptive sensory synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Hot Temperature; Male; Nociceptors; Pain; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamus | 1990 |