quinone methide has been researched along with Acute Liver Injury, Drug-Induced in 3 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 2 (66.67) | 2.80 |
Authors | Studies |
---|---|
Li, W; Liu, M; Peng, Y; Wang, A; Wang, Y; Zhao, G; Zhao, Q; Zheng, J | 1 |
Kobrlova, T; Korabecny, J; Koutsilieri, S; Kučera, R; Lauschke, VM; Novak, M; Prchal, L; Raisova-Stuchlikova, L; Sismanoglou, DC; Skalova, L; Soukup, O; Svobodova, B; Vajrychova, M; Zarybnicky, T | 1 |
Hayes, MA; Li, Y; Novalen, M; Sharma, AM; Uetrecht, J | 1 |
3 other study(ies) available for quinone methide and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A.
Topics: Activation, Metabolic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 CYP3A; Glutathione; Humans; Ketoconazole; Mice; Microsomes, Liver; Rats; Tolterodine Tartrate | 2023 |
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Humans; Indolequinones; Methamphetamine; Mice; Rats; Tacrine | 2023 |
Bioactivation of nevirapine to a reactive quinone methide: implications for liver injury.
Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; Female; Humans; Indolequinones; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Nevirapine; Oxidation-Reduction; Rats; Rats, Inbred BN; Steroid 16-alpha-Hydroxylase | 2012 |