Page last updated: 2024-11-02

quinone and Pain

quinone has been researched along with Pain in 16 studies

benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
" In addition, carrageenan-induced paw edema and p-benzoquinone-induced abdominal constriction models were used for the activity assessments."3.79Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models. ( Asakawa, Y; Küpeli Akkol, E; Özenoğlu Kiremit, H; Süntar, I; Tosun, A, 2013)
" For the anti-inflammatory activity, the carrageenan-induced hind paw edema and acetic acid-induced increased capillary permeability models were used, whereas for the antinociceptive activity, the p-benzoquinone-induced writhing and hot plate tests in mice were used."3.76Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. ( Akkol, EK; Baykal, T; Süntar, IP, 2010)
" solstitialis have been investigated by using p-benzoquinone-induced writhing reflex for antinociceptive activity and Freund's Complete Adjuvant-induced pyrexia model for antipyretic activity assessment in mice."3.75Sesquiterpene lactones with antinociceptive and antipyretic activity from two Centaurea species. ( Akkol, EK; Arif, R; Ergun, F; Yesilada, E, 2009)
"For the anti-inflammatory activity, carrageenan-induced and PGE(2)-induced hind paw edema models, and for the antinociceptive activity p-benzoquinone-induced writhing and hot plate tests in mice were employed."3.75A comparative study on the antinociceptive and anti-inflammatory activities of five Juniperus taxa. ( Akkol, EK; Güvenç, A; Yesilada, E, 2009)
" Anti-inflammatory and analgesic activities of the compounds were assessed in vivo by carrageenan-induced hind paw edema and p-benzoquinone induced abdominal contraction tests in mice, respectively."3.75Design and synthesis of some (S)-2-(6-methoxynaphthalen-2-yl)-N-substituted ethyl propanamide derivatives as potent non-ulcerogenic anti-inflammatory and analgesic agents. ( Berk, B; Erol, DD; Kupeli, E; Yesilada, E, 2009)
" For the anti-inflammatory activity assessment, carrageenan-induced hind paw edema and for the antinociceptive activity, p-benzoquinone-induced abdominal constriction tests were used."3.74Phenolic compounds of Sideritis ozturkii and their in vivo anti-inflammatory and antinociceptive activities. ( Caliş, I; Ezer, N; Küpeli, E; Sahin, FP; Yeşilada, E, 2007)
"In this study, amide derivatives of [6-(5-methyl-3-phenyl-pyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acid were synthesized and tested for their in vivo analgesic and anti-inflammatory activity by using the p-benzoquinone-induced writhing test and carrageenan-induced hind paw edema model, respectively."3.72Amide derivatives of [6-(5-methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds. ( Akoğlu, C; Banoglu, E; Küpeli, E; Sahin, MF; Unlü, S; Yeşilada, E, 2004)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (50.00)29.6817
2010's8 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hassanein, HH1
Georgey, HH2
Fouad, MA1
El Kerdawy, AM1
Said, MF2
Eberhardt, MJ1
Schillers, F1
Eberhardt, EM1
Risser, L1
de la Roche, J1
Herzog, C1
Echtermeyer, F1
Leffler, A1
Ragab, FA1
Abdel Gawad, NM1
Tosun, A1
Küpeli Akkol, E2
Süntar, I2
Özenoğlu Kiremit, H1
Asakawa, Y1
Akkol, EK4
Arif, R1
Ergun, F1
Yesilada, E8
Güvenç, A2
Berk, B1
Erol, DD1
Kupeli, E5
Süntar, IP1
Baykal, T1
Kırmızıbekmez, H1
Küçükboyacı, N1
Gören, AC1
Mandour, AH1
El-Sawy, ER1
Ebaid, MS1
Hassan, SM1
Keleş, H1
Yıldız, S1
Calış, I2
Banoglu, E1
Akoğlu, C1
Unlü, S1
Sahin, MF1
Tozkoparan, B1
Gökhan, N1
Ertan, M1
Sahin, FP1
Ezer, N1
Uludag, O1
Tunctan, B1
Altug, S1
Zengil, H1
Abacioglu, N1
Orhan, I1
Terzioğlu, S1

Other Studies

16 other studies available for quinone and Pain

ArticleYear
Synthesis and molecular docking of new imidazoquinazolinones as analgesic agents and selective COX-2 inhibitors.
    Future medicinal chemistry, 2017, Volume: 9, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Cyclooxygenase 2; Cyclo

2017
Reactive metabolites of acetaminophen activate and sensitize the capsaicin receptor TRPV1.
    Scientific reports, 2017, 10-06, Volume: 7, Issue:1

    Topics: Acetaminophen; Animals; Benzoquinones; Calcium; Capsaicin; Cell Death; Cysteine; Ganglia, Spinal; HE

2017
Synthesis of novel 1,3,4-trisubstituted pyrazoles as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Cyclooxygenase 1; Cycloox

2013
Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models.
    Pharmaceutical biology, 2013, Volume: 51, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Disease Models, Animal; E

2013
Sesquiterpene lactones with antinociceptive and antipyretic activity from two Centaurea species.
    Journal of ethnopharmacology, 2009, Mar-18, Volume: 122, Issue:2

    Topics: Analgesics; Animals; Benzoquinones; Centaurea; Fever; Freund's Adjuvant; Lactones; Male; Mice; Pain;

2009
A comparative study on the antinociceptive and anti-inflammatory activities of five Juniperus taxa.
    Journal of ethnopharmacology, 2009, Sep-07, Volume: 125, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Benzoquinones; Carrageenan; Dinopro

2009
Design and synthesis of some (S)-2-(6-methoxynaphthalen-2-yl)-N-substituted ethyl propanamide derivatives as potent non-ulcerogenic anti-inflammatory and analgesic agents.
    Arzneimittel-Forschung, 2009, Volume: 59, Issue:4

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Carrageenan; Drug Delivery

2009
Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L.
    Journal of medicinal food, 2010, Volume: 13, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Capillary Permeability; C

2010
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla

2012
Synthesis and potential biological activity of some novel 3-[(N-substituted indol-3-yl)methyleneamino]-6-amino-4-aryl-pyrano(2,3-c)pyrazole-5-carbonitriles and 3,6-diamino-4-(N-substituted indol-3-yl)pyrano(2,3-c)pyrazole-5-carbonitriles.
    Acta pharmaceutica (Zagreb, Croatia), 2012, Volume: 62, Issue:1

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Benzoquinones

2012
Biological activities of Pseudevernia furfuracea (L.) Zopf extracts and isolation of the active compounds.
    Journal of ethnopharmacology, 2012, Dec-18, Volume: 144, Issue:3

    Topics: Analgesics; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Ascomycota; Bact

2012
Amide derivatives of [6-(5-methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds.
    Archiv der Pharmazie, 2004, Volume: 337, Issue:1

    Topics: Acetates; Administration, Oral; Amides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal

2004
Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Capillary Per

2004
Phenolic compounds of Sideritis ozturkii and their in vivo anti-inflammatory and antinociceptive activities.
    Journal of ethnopharmacology, 2007, Jun-13, Volume: 112, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Edema; Flavones; Flavonoi

2007
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
    Chronobiology international, 2007, Volume: 24, Issue:3

    Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme I

2007
Bioassay-guided isolation of kaempferol-3-O-beta-D-galactoside with anti-inflammatory and antinociceptive activity from the aerial part of Calluna vulgaris L.
    Journal of ethnopharmacology, 2007, Oct-08, Volume: 114, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Calluna; Carrageenan

2007