quinone has been researched along with Leukemia in 5 studies
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic exposure to benzene results in progressive decline of hematopoietic function and may lead to the onset of various disorders, including aplastic anemia, myelodysplastic syndrome, and leukemia." | 3.72 | Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression. ( Abernethy, DJ; Faiola, B; Fuller, ES; Pluta, L; Recio, L; Rose, J; Wong, VA, 2004) |
| "Benzene is an established human and animal carcinogen." | 1.33 | Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene. ( Eastmond, DA; Hasegawa, L; Mondrala, ST, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OLMER, J | 1 |
| SOBESLAVSKY, C | 1 |
| SOCHMAN, J | 1 |
| MOTYCKA, K | 1 |
| Faiola, B | 1 |
| Fuller, ES | 1 |
| Wong, VA | 1 |
| Pluta, L | 1 |
| Abernethy, DJ | 1 |
| Rose, J | 1 |
| Recio, L | 1 |
| Eastmond, DA | 1 |
| Mondrala, ST | 1 |
| Hasegawa, L | 1 |
| Lévay, G | 1 |
| Ross, D | 1 |
| Bodell, WJ | 1 |
5 other studies available for quinone and Leukemia
| Article | Year |
|---|---|
[First therapeutic trials with the ethylene-quinone E 39].
Topics: Antineoplastic Agents; Benzoquinones; Carcinoma, Squamous Cell; Disease; Ethylenes; Humans; Leukemia | 1957 |
[Effect of certain benzoquinone-ethyleneimino derivatives on experiemental mouse leukemia].
Topics: Animals; Antineoplastic Agents; Benzoquinones; Leukemia; Leukemia, Experimental; Mice; Quinones | 1959 |
Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.
Topics: Animals; Apoptosis; Benzene; Benzoquinones; Carcinogens; Cell Cycle Proteins; Cell Transformation, N | 2004 |
Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene.
Topics: Benzene; Benzoquinones; Carcinogens; Dithiothreitol; DNA Topoisomerases, Type II; DNA, Kinetoplast; | 2005 |
Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow.
Topics: Animals; Benzoquinones; Biotransformation; Bone Marrow; Cell Line; DNA; DNA, Neoplasm; Humans; Hydro | 1993 |