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quinone and Leukemia, Myeloid, Acute

quinone has been researched along with Leukemia, Myeloid, Acute in 3 studies

benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Benzene is a known environmental pollutant with demonstrated leukemogenic activity."1.38How benzene and its metabolites affect human marrow derived mesenchymal stem cells. ( Amirizadeh, N; Hosseinkhani, S; Nazem, S; Sadeghizadeh, M; Zolghadr, F, 2012)
"Etoposide is a topoisomerase II poison that is used to treat a variety of human cancers."1.37Etoposide quinone is a redox-dependent topoisomerase II poison. ( Deweese, JE; Jacob, DA; Mercer, SL; Osheroff, N, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacob, DA1
Mercer, SL1
Osheroff, N1
Deweese, JE1
Zolghadr, F1
Sadeghizadeh, M1
Amirizadeh, N1
Hosseinkhani, S1
Nazem, S1
Hutt, AM1
Kalf, GF1

Other Studies

3 other studies available for quinone and Leukemia, Myeloid, Acute

ArticleYear
Etoposide quinone is a redox-dependent topoisomerase II poison.
    Biochemistry, 2011, Jun-28, Volume: 50, Issue:25

    Topics: Antigens, Neoplasm; Benzoquinones; Catechols; Dithiothreitol; DNA Adducts; DNA Damage; DNA Topoisome

2011
How benzene and its metabolites affect human marrow derived mesenchymal stem cells.
    Toxicology letters, 2012, Oct-17, Volume: 214, Issue:2

    Topics: Apoptosis; Benzene; Benzoquinones; Calcium-Binding Proteins; Caspases; Cell Survival; Chemokine CXCL

2012
Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
    Environmental health perspectives, 1996, Volume: 104 Suppl 6

    Topics: Animals; Benzene; Benzoquinones; Carcinogens; DNA Damage; DNA, Kinetoplast; Enzyme Inhibitors; Human

1996