quinone has been researched along with Leukemia, Myeloid, Acute in 3 studies
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzene is a known environmental pollutant with demonstrated leukemogenic activity." | 1.38 | How benzene and its metabolites affect human marrow derived mesenchymal stem cells. ( Amirizadeh, N; Hosseinkhani, S; Nazem, S; Sadeghizadeh, M; Zolghadr, F, 2012) |
| "Etoposide is a topoisomerase II poison that is used to treat a variety of human cancers." | 1.37 | Etoposide quinone is a redox-dependent topoisomerase II poison. ( Deweese, JE; Jacob, DA; Mercer, SL; Osheroff, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacob, DA | 1 |
| Mercer, SL | 1 |
| Osheroff, N | 1 |
| Deweese, JE | 1 |
| Zolghadr, F | 1 |
| Sadeghizadeh, M | 1 |
| Amirizadeh, N | 1 |
| Hosseinkhani, S | 1 |
| Nazem, S | 1 |
| Hutt, AM | 1 |
| Kalf, GF | 1 |
3 other studies available for quinone and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Etoposide quinone is a redox-dependent topoisomerase II poison.
Topics: Antigens, Neoplasm; Benzoquinones; Catechols; Dithiothreitol; DNA Adducts; DNA Damage; DNA Topoisome | 2011 |
How benzene and its metabolites affect human marrow derived mesenchymal stem cells.
Topics: Apoptosis; Benzene; Benzoquinones; Calcium-Binding Proteins; Caspases; Cell Survival; Chemokine CXCL | 2012 |
Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene.
Topics: Animals; Benzene; Benzoquinones; Carcinogens; DNA Damage; DNA, Kinetoplast; Enzyme Inhibitors; Human | 1996 |