quinone has been researched along with Leucocythaemia in 5 studies
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic exposure to benzene results in progressive decline of hematopoietic function and may lead to the onset of various disorders, including aplastic anemia, myelodysplastic syndrome, and leukemia." | 3.72 | Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression. ( Abernethy, DJ; Faiola, B; Fuller, ES; Pluta, L; Recio, L; Rose, J; Wong, VA, 2004) |
| "Benzene is an established human and animal carcinogen." | 1.33 | Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene. ( Eastmond, DA; Hasegawa, L; Mondrala, ST, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OLMER, J | 1 |
| SOBESLAVSKY, C | 1 |
| SOCHMAN, J | 1 |
| MOTYCKA, K | 1 |
| Faiola, B | 1 |
| Fuller, ES | 1 |
| Wong, VA | 1 |
| Pluta, L | 1 |
| Abernethy, DJ | 1 |
| Rose, J | 1 |
| Recio, L | 1 |
| Eastmond, DA | 1 |
| Mondrala, ST | 1 |
| Hasegawa, L | 1 |
| Lévay, G | 1 |
| Ross, D | 1 |
| Bodell, WJ | 1 |
5 other studies available for quinone and Leucocythaemia
| Article | Year |
|---|---|
[First therapeutic trials with the ethylene-quinone E 39].
Topics: Antineoplastic Agents; Benzoquinones; Carcinoma, Squamous Cell; Disease; Ethylenes; Humans; Leukemia | 1957 |
[Effect of certain benzoquinone-ethyleneimino derivatives on experiemental mouse leukemia].
Topics: Animals; Antineoplastic Agents; Benzoquinones; Leukemia; Leukemia, Experimental; Mice; Quinones | 1959 |
Exposure of hematopoietic stem cells to benzene or 1,4-benzoquinone induces gender-specific gene expression.
Topics: Animals; Apoptosis; Benzene; Benzoquinones; Carcinogens; Cell Cycle Proteins; Cell Transformation, N | 2004 |
Topoisomerase II inhibition by myeloperoxidase-activated hydroquinone: a potential mechanism underlying the genotoxic and carcinogenic effects of benzene.
Topics: Benzene; Benzoquinones; Carcinogens; Dithiothreitol; DNA Topoisomerases, Type II; DNA, Kinetoplast; | 2005 |
Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells, mouse bone marrow macrophages and human bone marrow.
Topics: Animals; Benzoquinones; Biotransformation; Bone Marrow; Cell Line; DNA; DNA, Neoplasm; Humans; Hydro | 1993 |