Page last updated: 2024-11-02

quinone and Innate Inflammatory Response

quinone has been researched along with Innate Inflammatory Response in 15 studies

benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).

Research Excerpts

ExcerptRelevanceReference
"Here, the aim was to investigate the role of circulating oxidized mitochondrial DNA (ox-mtDNA) in metabolic syndrome (MetS)-associated chronic inflammation and evaluate the effect of Mito-Quinone (MitoQ)-based antioxidant therapy on inflammation."4.31Increased levels of circulating oxidized mitochondrial DNA contribute to chronic inflammation in metabolic syndrome, and MitoQ-based antioxidant therapy alleviates this DNA-induced inflammation. ( Hu, X; Wen, C; Ye, W; Zeng, A, 2023)
" In this study we used CoQ0 (2,3-dimethoxy-5-methyl-1,4-benzoquinone, zero isoprenoid side-chains), a novel quinone derivative, and investigated its molecular actions against LPS-induced inflammation and redox imbalance in murine RAW264."3.83Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of LPS-induced inflammation and redox imbalance: Evidence from in vitro and in vivo studies. ( Chang, CT; Hseu, YC; Korivi, M; Liao, CH; Liao, JW; Lin, MW; Wu, JJ; Yang, HL, 2016)
" In addition, carrageenan-induced paw edema and p-benzoquinone-induced abdominal constriction models were used for the activity assessments."3.79Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models. ( Asakawa, Y; Küpeli Akkol, E; Özenoğlu Kiremit, H; Süntar, I; Tosun, A, 2013)
" jacquiniana, Scorzonera cinerea, Scorzonera eriophora, Scorzonera incisa and Scorzonera parviflora showed significant inhibitory effect on carrageenan and PGE(2)-induced hind paw edema model as well as on p-benzoquinone-induced abdominal constriction test."3.78Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects. ( Bahadır Acıkara, O; Ergene, B; Küpeli Akkol, E; Saltan Çitoğlu, G; Süntar, I, 2012)
" For the anti-inflammatory activity, the carrageenan-induced hind paw edema and acetic acid-induced increased capillary permeability models were used, whereas for the antinociceptive activity, the p-benzoquinone-induced writhing and hot plate tests in mice were used."3.76Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. ( Akkol, EK; Baykal, T; Süntar, IP, 2010)
"For the anti-inflammatory activity, carrageenan-induced and PGE(2)-induced hind paw edema models, and for the antinociceptive activity p-benzoquinone-induced writhing and hot plate tests in mice were employed."3.75A comparative study on the antinociceptive and anti-inflammatory activities of five Juniperus taxa. ( Akkol, EK; Güvenç, A; Yesilada, E, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's1 (6.67)29.6817
2010's11 (73.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Huang, FC1
Chan, WK1
Moriarty, KJ1
Zhang, DC1
Chang, MN1
He, W1
Yu, KT1
Zilberstein, A1
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Ye, W1
Wen, C1
Zeng, A1
Hu, X1
Gui, YH1
Liu, L1
Wu, W1
Zhang, Y1
Jia, ZL1
Shi, YP1
Kong, HT1
Liu, KC1
Jiao, WH1
Lin, HW1
Tosun, A1
Küpeli Akkol, E2
Süntar, I2
Özenoğlu Kiremit, H1
Asakawa, Y1
Hamsin, DE1
Hamid, RA1
Yazan, LS1
Taib, CN1
Yeong, LT1
Ghosh, A2
Ganguly, S1
Dey, N2
Banerjee, S1
Das, A2
Chattopadhyay, DJ2
Chatterjee, IB2
Hwang, D1
Son, BW1
Shin, PG1
Choi, JS1
Seo, YB1
Kim, GD1
Yang, HL1
Lin, MW1
Korivi, M1
Wu, JJ1
Liao, CH1
Chang, CT1
Liao, JW1
Hseu, YC1
Akkol, EK3
Güvenç, A1
Yesilada, E2
Süntar, IP1
Baykal, T1
Kırmızıbekmez, H1
Küçükboyacı, N1
Gören, AC1
Bahadır Acıkara, O1
Ergene, B1
Saltan Çitoğlu, G1
Mandour, AH1
El-Sawy, ER1
Ebaid, MS1
Hassan, SM1
Das, S1

Other Studies

15 other studies available for quinone and Innate Inflammatory Response

ArticleYear
Novel cytokine release inhibitors. Part I: Triterpenes.
    Bioorganic & medicinal chemistry letters, 1998, Jul-21, Volume: 8, Issue:14

    Topics: Animals; Cytokines; Humans; In Vitro Techniques; Inflammation; Molecular Structure; Rats; Triterpene

1998
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Increased levels of circulating oxidized mitochondrial DNA contribute to chronic inflammation in metabolic syndrome, and MitoQ-based antioxidant therapy alleviates this DNA-induced inflammation.
    Molecular and cellular endocrinology, 2023, 01-15, Volume: 560

    Topics: Animals; Antioxidants; Cell-Free Nucleic Acids; DNA, Mitochondrial; Hydrogen Peroxide; Inflammation;

2023
Discovery of nitrogenous sesquiterpene quinone derivatives from sponge Dysidea septosa with anti-inflammatory activity in vivo zebrafish model.
    Bioorganic chemistry, 2020, Volume: 94

    Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Cells, Cultured; Copper Sulfate; Crystallography,

2020
Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models.
    Pharmaceutical biology, 2013, Volume: 51, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Disease Models, Animal; E

2013
Ardisia crispa roots inhibit cyclooxygenase and suppress angiogenesis.
    BMC complementary and alternative medicine, 2014, Mar-19, Volume: 14

    Topics: Angiogenesis Inhibitors; Animals; Ardisia; Benzoquinones; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo

2014
Causation of cigarette smoke-induced emphysema by p-benzoquinone and its prevention by vitamin C.
    American journal of respiratory cell and molecular biology, 2015, Volume: 52, Issue:3

    Topics: Animals; Apoptosis; Ascorbic Acid; Benzoquinones; Disease Models, Animal; Guinea Pigs; Inflammation;

2015
Toluhydroquinone from Aspergillus sp. suppress inflammatory mediators via nuclear factor-κB and mitogen-activated protein kinases pathways in lipopolysaccharide-induced RAW264.7 cells.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Aspergillus; Benzoquinones; Cell Line; Cyclooxygenase 2; Dinopros

2015
Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of LPS-induced inflammation and redox imbalance: Evidence from in vitro and in vivo studies.
    Biochimica et biophysica acta, 2016, Volume: 1859, Issue:2

    Topics: Animals; Benzoquinones; Cyclooxygenase 2; Gene Expression Regulation; Heme Oxygenase-1; Inflammation

2016
A comparative study on the antinociceptive and anti-inflammatory activities of five Juniperus taxa.
    Journal of ethnopharmacology, 2009, Sep-07, Volume: 125, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Benzoquinones; Carrageenan; Dinopro

2009
Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L.
    Journal of medicinal food, 2010, Volume: 13, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Capillary Permeability; C

2010
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla

2012
Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects.
    Journal of ethnopharmacology, 2012, Mar-27, Volume: 140, Issue:2

    Topics: Abdominal Pain; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Chlorogen

2012
Synthesis and potential biological activity of some novel 3-[(N-substituted indol-3-yl)methyleneamino]-6-amino-4-aryl-pyrano(2,3-c)pyrazole-5-carbonitriles and 3,6-diamino-4-(N-substituted indol-3-yl)pyrano(2,3-c)pyrazole-5-carbonitriles.
    Acta pharmaceutica (Zagreb, Croatia), 2012, Volume: 62, Issue:1

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Benzoquinones

2012
Molecular and cellular mechanisms of cigarette smoke-induced myocardial injury: prevention by vitamin C.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Adult; Aged; Animals; Apoptosis; Ascorbic Acid; Benzoquinones; Disease Progression; Enzyme Activatio

2012