Page last updated: 2024-11-02

quinone and Disease Models, Animal

quinone has been researched along with Disease Models, Animal in 14 studies

benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" In addition, carrageenan-induced paw edema and p-benzoquinone-induced abdominal constriction models were used for the activity assessments."3.79Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models. ( Asakawa, Y; Küpeli Akkol, E; Özenoğlu Kiremit, H; Süntar, I; Tosun, A, 2013)
" jacquiniana, Scorzonera cinerea, Scorzonera eriophora, Scorzonera incisa and Scorzonera parviflora showed significant inhibitory effect on carrageenan and PGE(2)-induced hind paw edema model as well as on p-benzoquinone-induced abdominal constriction test."3.78Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects. ( Bahadır Acıkara, O; Ergene, B; Küpeli Akkol, E; Saltan Çitoğlu, G; Süntar, I, 2012)
" For the anti-inflammatory activity, the carrageenan-induced hind paw edema and acetic acid-induced increased capillary permeability models were used, whereas for the antinociceptive activity, the p-benzoquinone-induced writhing and hot plate tests in mice were used."3.76Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L. ( Akkol, EK; Baykal, T; Süntar, IP, 2010)
"The two autoimmune diseases are not only linked by a concordance of clinical presentations and an autoimmune/oxidative stress-mediated toxicity pathogenesis but also by an apparent biochemical commonality."1.51Vitiligo and Hashimoto's thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis. ( Bellanti, JA; Calderone, R; Li, D; Liang, G, 2019)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's9 (64.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Kumar, S1
Malachowski, WP1
DuHadaway, JB1
LaLonde, JM1
Carroll, PJ1
Jaller, D1
Metz, R1
Prendergast, GC1
Muller, AJ1
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Nilsson, JLÅ1
Blomgren, A1
Nilsson, UJ1
Högestätt, ED1
Grundemar, L1
Li, D1
Liang, G1
Calderone, R1
Bellanti, JA1
Tosun, A1
Küpeli Akkol, E2
Süntar, I2
Özenoğlu Kiremit, H1
Asakawa, Y1
Ghosh, A1
Ganguly, S1
Dey, N1
Banerjee, S1
Das, A1
Chattopadhyay, DJ1
Chatterjee, IB1
Bagh, MB1
Maiti, AK1
Jana, S1
Banerjee, K1
Roy, A1
Chakrabarti, S1
Süntar, IP1
Akkol, EK2
Baykal, T1
Kırmızıbekmez, H1
Küçükboyacı, N1
Gören, AC1
Yesilada, E1
Bahadır Acıkara, O1
Ergene, B1
Saltan Çitoğlu, G1
Mandour, AH1
El-Sawy, ER1
Ebaid, MS1
Hassan, SM1
De Long, MJ1
Prochaska, HJ1
Talalay, P1
Asanuma, M1
Miyazaki, I1
Diaz-Corrales, FJ1
Shimizu, M1
Tanaka, K1
Ogawa, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Placebo Controlled Trial of Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke[NCT04918719]Phase 2118 participants (Anticipated)Interventional2021-06-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

14 other studies available for quinone and Disease Models, Animal

ArticleYear
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cell Survival; Computer Simulatio

2008
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
N,N'-Bis(2-mercaptoethyl)isophthalamide Binds Electrophilic Paracetamol Metabolites and Prevents Paracetamol-Induced Liver Toxicity.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antidotes; B

2018
Vitiligo and Hashimoto's thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis.
    Medical hypotheses, 2019, Volume: 128

    Topics: Animals; Autoimmune Diseases; Autoimmunity; Benzoquinones; Disease Models, Animal; Hashimoto Disease

2019
Phytochemical investigations and bioactivity evaluation of liverworts as a function of anti-inflammatory and antinociceptive properties in animal models.
    Pharmaceutical biology, 2013, Volume: 51, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Disease Models, Animal; E

2013
Causation of cigarette smoke-induced emphysema by p-benzoquinone and its prevention by vitamin C.
    American journal of respiratory cell and molecular biology, 2015, Volume: 52, Issue:3

    Topics: Animals; Apoptosis; Ascorbic Acid; Benzoquinones; Disease Models, Animal; Guinea Pigs; Inflammation;

2015
Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's disease.
    Free radical research, 2008, Volume: 42, Issue:6

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Benzoquinones; Brain; Disease Models, Animal; Dopam

2008
Assessment of anti-inflammatory and antinociceptive activities of Olea europaea L.
    Journal of medicinal food, 2010, Volume: 13, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Capillary Permeability; C

2010
Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Biological Assay; Capilla

2012
Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects.
    Journal of ethnopharmacology, 2012, Mar-27, Volume: 140, Issue:2

    Topics: Abdominal Pain; Analgesics; Animals; Anti-Inflammatory Agents; Benzoquinones; Carrageenan; Chlorogen

2012
Synthesis and potential biological activity of some novel 3-[(N-substituted indol-3-yl)methyleneamino]-6-amino-4-aryl-pyrano(2,3-c)pyrazole-5-carbonitriles and 3,6-diamino-4-(N-substituted indol-3-yl)pyrano(2,3-c)pyrazole-5-carbonitriles.
    Acta pharmaceutica (Zagreb, Croatia), 2012, Volume: 62, Issue:1

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Benzoquinones

2012
Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:3

    Topics: Animals; Antioxidants; Azo Compounds; Benzoquinones; Carcinogens; Chemical Phenomena; Chemistry; Cou

1986
Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.
    Neurological research, 2005, Volume: 27, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Benzoquinones;

2005