quinone has been researched along with Chromosomal Breakage in 2 studies
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benzene is a human carcinogen that induces hematopoietic malignancies." | 1.33 | Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites. ( Bender, RP; Lindsey, RH; Osheroff, N, 2005) |
| "Benzoquinone was the most damaging compound when tested under more physiological conditions, thereby supporting the general observation that it is the most myelotoxic benzene metabolite." | 1.31 | Influence of culture conditions on the DNA-damaging effect of benzene and its metabolites in human peripheral blood mononuclear cells. ( De Bartolomeo, A; Fabiani, R; Lepore, L; Morozzi, G; Rosignoli, P; Scamosci, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindsey, RH | 1 |
| Bender, RP | 1 |
| Osheroff, N | 1 |
| Fabiani, R | 1 |
| De Bartolomeo, A | 1 |
| Rosignoli, P | 1 |
| Scamosci, M | 1 |
| Lepore, L | 1 |
| Morozzi, G | 1 |
2 other studies available for quinone and Chromosomal Breakage
| Article | Year |
|---|---|
Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites.
Topics: Antigens, Neoplasm; Benzene; Benzoquinones; Chromosome Breakage; DNA Damage; DNA Topoisomerases, Typ | 2005 |
Influence of culture conditions on the DNA-damaging effect of benzene and its metabolites in human peripheral blood mononuclear cells.
Topics: Benzene; Benzene Derivatives; Benzoquinones; Catechols; Cell Survival; Cells, Cultured; Chromosome B | 2001 |