Page last updated: 2024-11-02

quinone and Chemical and Drug Induced Liver Injury

quinone has been researched along with Chemical and Drug Induced Liver Injury in 4 studies

benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
" In conclusion, our study revealed the toxic effects of 6PPD and 6PPDQ exposure on multi-endpoints in the liver of mice and improve our understanding of the health risks of 6PPD and 6PPDQ to mammals."1.91Oral exposure to tire rubber-derived contaminant 6PPD and 6PPD-quinone induce hepatotoxicity in mice. ( Di, S; Fang, C; Fang, L; Jin, Y; Wang, C; Wang, X; Yu, Y, 2023)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Fang, L1
Fang, C1
Di, S1
Yu, Y1
Wang, C1
Wang, X1
Jin, Y1
Ding, CH1
Zhu, H1
Nilsson, JLÅ1
Blomgren, A1
Nilsson, UJ1
Högestätt, ED1
Grundemar, L1
Leclerc, E1
Hamon, J1
Claude, I1
Jellali, R1
Naudot, M1
Bois, F1

Other Studies

4 other studies available for quinone and Chemical and Drug Induced Liver Injury

ArticleYear
Oral exposure to tire rubber-derived contaminant 6PPD and 6PPD-quinone induce hepatotoxicity in mice.
    The Science of the total environment, 2023, Apr-15, Volume: 869

    Topics: Animals; Chemical and Drug Induced Liver Injury; Mammals; Mice; Mice, Inbred C57BL; Quinones; Rubber

2023
Isatidis Folium alleviates acetaminophen-induced liver injury in mice by enhancing the endogenous antioxidant system.
    Environmental toxicology, 2020, Volume: 35, Issue:11

    Topics: Acetaminophen; Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Chemica

2020
N,N'-Bis(2-mercaptoethyl)isophthalamide Binds Electrophilic Paracetamol Metabolites and Prevents Paracetamol-Induced Liver Toxicity.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antidotes; B

2018
Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion.
    Cell biology and toxicology, 2015, Volume: 31, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Cell Line, Tumor; Chemical an

2015