Page last updated: 2024-11-02

quinone and Carcinoma, Hepatocellular

quinone has been researched along with Carcinoma, Hepatocellular in 3 studies

benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).

Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.

Research Excerpts

ExcerptRelevanceReference
"The resistance of BQ-treated cells to necrosis could be due to increased cellular GSH and formation of BQ-GSH conjugates which are less toxic than free BQ, minimal toxicity being provided by GS4-BHQ."5.35Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione. ( Bagrel, D; Baigi, MG; Beley, M; Brault, L; Gaüzère, F; Hilali, RE; Néguesque, A, 2008)
"The resistance of BQ-treated cells to necrosis could be due to increased cellular GSH and formation of BQ-GSH conjugates which are less toxic than free BQ, minimal toxicity being provided by GS4-BHQ."1.35Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione. ( Bagrel, D; Baigi, MG; Beley, M; Brault, L; Gaüzère, F; Hilali, RE; Néguesque, A, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baigi, MG1
Brault, L1
Néguesque, A1
Beley, M1
Hilali, RE1
Gaüzère, F1
Bagrel, D1
Benites, J1
Rojo, L1
Valderrama, JA1
Taper, H1
Calderon, PB1
Burczynski, ME1
Lin, HK1
Penning, TM1

Other Studies

3 other studies available for quinone and Carcinoma, Hepatocellular

ArticleYear
Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:6

    Topics: Animals; Apoptosis; Benzoquinones; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Fe

2008
Part 1: Effect of vitamin C on the biological activity of two euryfurylbenzoquinones on TLT, a murine hepatoma cell line.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Ascorbic Acid; Benzoquinones; Carcinoma, Hep

2008
Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
    Cancer research, 1999, Feb-01, Volume: 59, Issue:3

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benzopyrenes; Benzoquinones; beta

1999