quinone has been researched along with Breast Neoplasms in 8 studies
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.
1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The resistance of BQ-treated cells to necrosis could be due to increased cellular GSH and formation of BQ-GSH conjugates which are less toxic than free BQ, minimal toxicity being provided by GS4-BHQ." | 5.35 | Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione. ( Bagrel, D; Baigi, MG; Beley, M; Brault, L; Gaüzère, F; Hilali, RE; Néguesque, A, 2008) |
| "Tamoxifen remains the endocrine therapy of choice in the treatment of all stages of hormone-dependent breast cancer." | 3.71 | Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones. ( Bolton, JL; van Breemen, RB; Yang, Y; Yao, D; Yu, L; Zhang, F, 2001) |
| "Moreover, SV37 inhibits growth of breast cancer cell lines." | 1.42 | A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. ( Bagrel, D; Bana, E; Cerella, C; Chaimbault, P; Dicato, M; Diederich, M; Kirsch, G; Sibille, E; Valente, S, 2015) |
| "The resistance of BQ-treated cells to necrosis could be due to increased cellular GSH and formation of BQ-GSH conjugates which are less toxic than free BQ, minimal toxicity being provided by GS4-BHQ." | 1.35 | Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione. ( Bagrel, D; Baigi, MG; Beley, M; Brault, L; Gaüzère, F; Hilali, RE; Néguesque, A, 2008) |
| "Cytotoxicity studies in the human breast cancer cell lines S30 and MDA-MB-231 showed that 7-hydroxyraloxifene was more toxic than raloxifene in both cell lines." | 1.32 | Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones. ( Bolton, JL; Li, W; Liu, H; Luckie, C; Thatcher, GR; van Breemen, RB; Yu, L; Zhang, F, 2004) |
| "Diaziquone (AZQ) is a substrate for this NAD(P)H oxidoreductase active S9 fraction as judged by its enzymatic reduction detected spectrophotometrically and by electron spin resonance spectroscopy." | 1.28 | The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity. ( Fisher, GR; Gutierrez, PL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibacache, JA | 1 |
| Faundes, J | 1 |
| Montoya, M | 1 |
| Mejías, S | 1 |
| Valderrama, JA | 1 |
| Bana, E | 1 |
| Sibille, E | 1 |
| Valente, S | 1 |
| Cerella, C | 1 |
| Chaimbault, P | 1 |
| Kirsch, G | 1 |
| Dicato, M | 1 |
| Diederich, M | 1 |
| Bagrel, D | 2 |
| Lin, C | 2 |
| Chen, DR | 2 |
| Wang, SL | 1 |
| Hsieh, WC | 1 |
| Yu, WF | 1 |
| Wang, TW | 2 |
| Tsai, CH | 2 |
| Wei, HH | 2 |
| Tsuang, BJ | 1 |
| Lin, PH | 2 |
| Baigi, MG | 1 |
| Brault, L | 1 |
| Néguesque, A | 1 |
| Beley, M | 1 |
| Hilali, RE | 1 |
| Gaüzère, F | 1 |
| Chen, ST | 1 |
| Chen, GJ | 1 |
| Yang, TC | 1 |
| Yu, L | 2 |
| Liu, H | 1 |
| Li, W | 1 |
| Zhang, F | 2 |
| Luckie, C | 1 |
| van Breemen, RB | 2 |
| Thatcher, GR | 1 |
| Bolton, JL | 2 |
| Yao, D | 1 |
| Yang, Y | 1 |
| Fisher, GR | 1 |
| Gutierrez, PL | 1 |
8 other studies available for quinone and Breast Neoplasms
| Article | Year |
|---|---|
Preparation of Novel Homodimers Derived from Cytotoxic Isoquinolinequinones. A Twin Drug Approach.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Line, Tumor | 2018 |
A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death.
Topics: Apoptosis; Benzoquinones; Breast Neoplasms; cdc25 Phosphatases; Cell Line, Tumor; Cell Proliferation | 2015 |
Cumulative body burdens of polycyclic aromatic hydrocarbons associated with estrogen bioactivation in pregnant women: protein adducts as biomarkers of exposure.
Topics: Adult; Benzoquinones; Biomarkers; Body Burden; Breast Neoplasms; Environmental Exposure; Estradiol; | 2014 |
Apoptosis/necrosis switch in two different cancer cell lines: influence of benzoquinone- and hydrogen peroxide-induced oxidative stress intensity, and glutathione.
Topics: Animals; Apoptosis; Benzoquinones; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Fe | 2008 |
Characterization of estrogen quinone-derived protein adducts and their identification in human serum albumin derived from breast cancer patients and healthy controls.
Topics: Acetylcysteine; Adult; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogens; Fema | 2011 |
Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones.
Topics: Animals; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Glutathione; Huma | 2004 |
Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Survival; Deoxyribonucleosides | 2001 |
The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity.
Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Breast Neoplasms; Cell-Free System; Electron Spin | 1991 |