quinolinic acid has been researched along with Stroke in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cryptotanshinone (CTS), a major constituent from the roots of Salvia miltiorrhiza (Danshen), is widely used in the treatment of coronary heart disease, stroke and less commonly Alzheimer's disease." | 7.74 | Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier. ( Cao, J; Chan, E; Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW, 2007) |
| "Cryptotanshinone (CTS), a major constituent from the roots of Salvia miltiorrhiza (Danshen), is widely used in the treatment of coronary heart disease, stroke and less commonly Alzheimer's disease." | 3.74 | Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier. ( Cao, J; Chan, E; Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW, 2007) |
| "Strokes are becoming less severe due to increased numbers of intensive care units and improved treatments." | 1.62 | Increased serum QUIN/KYNA is a reliable biomarker of post-stroke cognitive decline. ( Callebert, J; Chabriat, H; Cogo, A; Huberfeld, G; Kubis, N; Launay, JM; Maïer, B; Mangin, G; Mazighi, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cogo, A | 1 |
| Mangin, G | 1 |
| Maïer, B | 1 |
| Callebert, J | 1 |
| Mazighi, M | 1 |
| Chabriat, H | 1 |
| Launay, JM | 1 |
| Huberfeld, G | 1 |
| Kubis, N | 1 |
| Koo, YS | 1 |
| Kim, H | 1 |
| Park, JH | 1 |
| Kim, MJ | 1 |
| Shin, YI | 1 |
| Choi, BT | 1 |
| Lee, SY | 1 |
| Shin, HK | 1 |
| Yu, XY | 1 |
| Lin, SG | 1 |
| Chen, X | 1 |
| Zhou, ZW | 1 |
| Liang, J | 1 |
| Duan, W | 1 |
| Chowbay, B | 1 |
| Wen, JY | 1 |
| Chan, E | 1 |
| Cao, J | 1 |
| Li, CG | 1 |
| Zhou, SF | 1 |
3 other studies available for quinolinic acid and Stroke
| Article | Year |
|---|---|
Increased serum QUIN/KYNA is a reliable biomarker of post-stroke cognitive decline.
Topics: Animals; Biomarkers; Brain; Brain Ischemia; Cognitive Dysfunction; Diabetes Mellitus, Experimental; | 2021 |
Indoleamine 2,3-Dioxygenase-Dependent Neurotoxic Kynurenine Metabolism Contributes to Poststroke Depression Induced in Mice by Ischemic Stroke along with Spatial Restraint Stress.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Animals; Brain Ischemia; Depressive Disorder; Indoleamine-Pyr | 2018 |
Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
Topics: Alzheimer Disease; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Tran | 2007 |