quinolinic acid has been researched along with Striatonigral Atrophy in 4 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present experiment we studied the ability of embryonic striatal grafts to protect against striatal quinolinic acid (QA)-induced excitotoxicity in a previously established double lesion rat model of striatonigral degeneration (SND), the neuropathological substrate of parkinsonism associated with multiple system atrophy (MSA)." | 3.70 | Failure of neuroprotection by embryonic striatal grafts in a double lesion rat model of striatonigral degeneration (multiple system atrophy). ( Humpel, C; Levivier, M; Poewe, W; Puschban, Z; Scherfler, C; Seppi, K; Stefanova, N; Waldner, R; Wenning, GK, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaindlstorfer, C | 1 |
| Stefanova, N | 2 |
| Garcia, J | 1 |
| Krismer, F | 1 |
| Döbrössy, M | 1 |
| Göbel, G | 1 |
| Jellinger, K | 2 |
| Granata, R | 1 |
| Wenning, GK | 3 |
| Yoon, HH | 1 |
| Kim, YH | 1 |
| Shin, ES | 1 |
| Jeon, SR | 1 |
| Puschban, Z | 2 |
| Waldner, R | 1 |
| Seppi, K | 1 |
| Humpel, C | 1 |
| Scherfler, C | 2 |
| Levivier, M | 1 |
| Poewe, W | 2 |
| Ghorayeb, I | 1 |
| Goebel, GP | 1 |
| Tison, F | 1 |
4 other studies available for quinolinic acid and Striatonigral Atrophy
| Article | Year |
|---|---|
L-dopa response pattern in a rat model of mild striatonigral degeneration.
Topics: Animals; Behavior, Animal; Corpus Striatum; Denervation; Disease Models, Animal; Levodopa; Motor Act | 2019 |
A rat model of striatonigral degeneration generated by simultaneous injection of 6-hydroxydopamine into the medial forebrain bundle and quinolinic acid into the striatum.
Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Mem | 2014 |
Failure of neuroprotection by embryonic striatal grafts in a double lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Animals; Apomorphine; Autoradiography; Binding, Competitive; Brain Tissue Transplantation; Corpus St | 2000 |
Complex motor disturbances in a sequential double lesion rat model of striatonigral degeneration (multiple system atrophy).
Topics: Animals; Corpus Striatum; Disease Models, Animal; Glial Fibrillary Acidic Protein; Male; Motor Activ | 2000 |