quinolinic acid has been researched along with Status Epilepticus in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although some ITES syndromes have recognisable MRI neuroimaging phenotypes, there are otherwise few biomarkers of disease." | 5.91 | CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection-triggered encephalopathy syndromes. ( Andrews, PI; Ardern-Holmes, S; Bandodkar, S; Calvert, S; Dale, RC; Gill, D; Gupta, S; Han, VX; Kandula, T; Kothur, K; Malone, S; Menezes, MP; Mohammad, S; Patel, S; Subramanian, G; Thomas, T; Troedson, C; Waak, M; Yan, J, 2023) |
| "Although some ITES syndromes have recognisable MRI neuroimaging phenotypes, there are otherwise few biomarkers of disease." | 1.91 | CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection-triggered encephalopathy syndromes. ( Andrews, PI; Ardern-Holmes, S; Bandodkar, S; Calvert, S; Dale, RC; Gill, D; Gupta, S; Han, VX; Kandula, T; Kothur, K; Malone, S; Menezes, MP; Mohammad, S; Patel, S; Subramanian, G; Thomas, T; Troedson, C; Waak, M; Yan, J, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Dale, RC | 1 |
| Thomas, T | 1 |
| Patel, S | 1 |
| Han, VX | 1 |
| Kothur, K | 1 |
| Troedson, C | 1 |
| Gupta, S | 1 |
| Gill, D | 1 |
| Malone, S | 1 |
| Waak, M | 1 |
| Calvert, S | 1 |
| Subramanian, G | 1 |
| Andrews, PI | 1 |
| Kandula, T | 1 |
| Menezes, MP | 1 |
| Ardern-Holmes, S | 1 |
| Mohammad, S | 1 |
| Bandodkar, S | 1 |
| Yan, J | 1 |
| McLin, JP | 1 |
| Thompson, LM | 1 |
| Lusis, AJ | 1 |
| Davis, RC | 1 |
| Steward, O | 1 |
| Speciale, C | 1 |
| Schwarcz, R | 1 |
3 other studies available for quinolinic acid and Status Epilepticus
| Article | Year |
|---|---|
CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection-triggered encephalopathy syndromes.
Topics: Biomarkers; Brain Diseases; Chromatography, Liquid; Encephalitis; Humans; Kynurenine; Neopterin; Neu | 2023 |
Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid.
Topics: Animals; Chromosomes, Mammalian; Corpus Striatum; Disease Susceptibility; Excitatory Amino Acid Agon | 2008 |
Effect of systemic kainate administration on cerebral quinolinic acid metabolism in the rat.
Topics: Animals; Brain; Glutamate Decarboxylase; Kainic Acid; Male; Oxidoreductases; Pentosyltransferases; P | 1988 |