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quinolinic acid and Renal Insufficiency

quinolinic acid has been researched along with Renal Insufficiency in 3 studies

Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"Marked increases in metabolites of the L-tryptophan-kynurenine pathway, L-kynurenine and quinolinic acid (Quin), were observed in serum and cerebrospinal fluid (CSF) of both the rat and human with renal insufficiency."7.70Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency. ( Fujigaki, S; Fujii, H; Heyes, MP; Noma, A; Saito, K; Seishima, M; Shibata, K; Takemura, M; Wada, H, 2000)
"Marked increases in metabolites of the L-tryptophan-kynurenine pathway, L-kynurenine and quinolinic acid (Quin), were observed in serum and cerebrospinal fluid (CSF) of both the rat and human with renal insufficiency."3.70Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency. ( Fujigaki, S; Fujii, H; Heyes, MP; Noma, A; Saito, K; Seishima, M; Shibata, K; Takemura, M; Wada, H, 2000)
" We need to pay attention to the dosage of ceftazidime and to the appearance of neurological symptoms."1.72Ceftazidime encephalopathy developed without the elevation of cerebrospinal fluid concentration of ceftazidime: A case report of two cases. ( Fujii, K; Hasegawa, N; Hosoya, K; Kato, A; Kobayashi, E; Komatsu, M; Matsumoto, K; Ryuzaki, M; Taguchi, K; Toda, M; Yoshifuji, A, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Toda, M1
Yoshifuji, A1
Hosoya, K1
Taguchi, K1
Komatsu, M1
Kobayashi, E1
Fujii, K1
Kato, A1
Hasegawa, N1
Matsumoto, K1
Ryuzaki, M1
Saito, K1
Fujigaki, S1
Heyes, MP1
Shibata, K2
Takemura, M1
Fujii, H1
Wada, H1
Noma, A1
Seishima, M1
Fukuwatari, T1
Morikawa, Y1
Hayakawa, F1
Sugimoto, E1

Other Studies

3 other studies available for quinolinic acid and Renal Insufficiency

ArticleYear
Ceftazidime encephalopathy developed without the elevation of cerebrospinal fluid concentration of ceftazidime: A case report of two cases.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022, Volume: 28, Issue:12

    Topics: Aged, 80 and over; Brain Diseases; Ceftazidime; Humans; Male; Peritoneal Dialysis; Quinolinic Acid;

2022
Mechanism of increases in L-kynurenine and quinolinic acid in renal insufficiency.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:3

    Topics: Adult; Albuminuria; Animals; Carboxy-Lyases; Enzyme Inhibitors; Female; Humans; Hydrolases; Kynureni

2000
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:10

    Topics: 3-Hydroxyanthranilic Acid; Adenine; Animals; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Quino

2001