Page last updated: 2024-10-20

quinolinic acid and Parkinson Disease, Secondary

quinolinic acid has been researched along with Parkinson Disease, Secondary in 6 studies

Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.

Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Thomsen, MB1
Jacobsen, J1
Lillethorup, TP1
Schacht, AC1
Simonsen, M1
Romero-Ramos, M1
Brooks, DJ1
Landau, AM1
Schapira, AH1
Miranda, AF1
Sutton, MA1
Beninger, RJ1
Jhamandas, K1
Boegman, RJ1
Guzman, R1
Lövblad, KO1
Meyer, M1
Spenger, C1
Schroth, G1
Widmer, HR1
Oo, TF1
Siman, R1
Burke, RE1
Burton, S1
Daya, S1
Potgieter, B1

Reviews

1 review available for quinolinic acid and Parkinson Disease, Secondary

ArticleYear
The use of toxins to elucidate neural function and disease.
    Current opinion in neurology and neurosurgery, 1993, Volume: 6, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Brain; Brain Diseases; Disease Models, Animal; Humans;

1993

Other Studies

5 other studies available for quinolinic acid and Parkinson Disease, Secondary

ArticleYear
In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:4

    Topics: Animals; Anticonvulsants; Autoradiography; Corpus Striatum; Female; Huntington Disease; Hydroxydopam

2021
Quinolinic acid lesion of the nigrostriatal pathway: effect on turning behaviour and protection by elevation of endogenous kynurenic acid in Rattus norvegicus.
    Neuroscience letters, 1999, Mar-05, Volume: 262, Issue:2

    Topics: Alanine; Animals; Corpus Striatum; Excitatory Amino Acid Antagonists; Hydrolases; Kynurenic Acid; Ky

1999
Imaging the rat brain on a 1.5 T clinical MR-scanner.
    Journal of neuroscience methods, 2000, Apr-01, Volume: 97, Issue:1

    Topics: Animals; Artifacts; Blood-Brain Barrier; Brain; Brain Tissue Transplantation; Female; Huntington Dis

2000
Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra.
    Experimental neurology, 2002, Volume: 175, Issue:1

    Topics: Actins; Animals; Antibody Specificity; Apoptosis; Caspases; Cell Compartmentation; Cell Nucleus; Cyt

2002
Melatonin modulates apomorphine-induced rotational behaviour.
    Experientia, 1991, May-15, Volume: 47, Issue:5

    Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Hun

1991