quinolinic acid has been researched along with Otitis Media with Effusion in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors." | 5.29 | Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994) |
| " The levels of HIF-1α, NO, and quinolinic acid (QUIN) in the middle ear effusion and serum of these patients were investigated." | 3.78 | Effects of hypoxia-inducible factor 1α on bone conduction impairment in otitis media with effusion. ( Chen, ZB; Cheng, L; Tian, HQ; Wang, YQ; Xing, GQ; Xu, X; Zhou, H, 2012) |
| "Our study investigated the neurotoxicity of quinolinic acid (QA) to spiral ganglion cells (SGCs), observed the protective effects of N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 and magnesium ions on the QA-induced injury to SGCs, and analyzed the role of QA in otitis media with effusion (OME)-induced sensorineural hearing loss (SNHL)." | 3.76 | Neurotoxicity of quinolinic acid to spiral ganglion cells in rats. ( He, Y; Xiao, H; Yang, C; Zheng, N, 2010) |
| "Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors." | 1.29 | Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, H | 1 |
| Yang, C | 1 |
| He, Y | 1 |
| Zheng, N | 1 |
| Zhou, H | 1 |
| Chen, ZB | 1 |
| Tian, HQ | 1 |
| Xu, X | 1 |
| Wang, YQ | 1 |
| Xing, GQ | 1 |
| Cheng, L | 1 |
| Yellon, RF | 1 |
| Rose, E | 1 |
| Kenna, MA | 1 |
| Doyle, WJ | 1 |
| Casselbrant, M | 1 |
| Diven, WF | 1 |
| Whiteside, TL | 1 |
| Swarts, JD | 1 |
| Heyes, MP | 1 |
3 other studies available for quinolinic acid and Otitis Media with Effusion
| Article | Year |
|---|---|
Neurotoxicity of quinolinic acid to spiral ganglion cells in rats.
Topics: Animals; Animals, Newborn; Apoptosis; Calcium; Cells, Cultured; Dizocilpine Maleate; Hearing Loss, S | 2010 |
Effects of hypoxia-inducible factor 1α on bone conduction impairment in otitis media with effusion.
Topics: Adolescent; Adult; Audiometry, Pure-Tone; Auditory Threshold; Bone Conduction; Child; Female; Hearin | 2012 |
Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions.
Topics: Animals; Audiometry, Evoked Response; Child; Chinchilla; Cochlea; Gas Chromatography-Mass Spectromet | 1994 |