quinolinic acid has been researched along with Movement Disorders in 9 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With the intent of producing a more reliable behavioral model of Huntington disease, anatomically-defined lesions of limited size were produced by magnetic resonance imaging-guided stereotaxic injection of quinolinic acid in specific regions within the caudate and putamen of rhesus monkeys." | 3.69 | Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease. ( Brownell, AL; Burns, LH; Deacon, TW; Isacson, O; Jenkins, BG; Pakzaban, P; Tatter, SB, 1995) |
| "These are astrocytosis, up-regulation of mRNA encoding the neuropeptide somatostatin (SRIF) and an increased expression of MHC Class II antigen." | 2.39 | Neuronal substrates for SIV encephalopathy. ( da Cunha, A; Eiden, LE; Rausch, DM, 1994) |
| " Following baseline, rats were subjected to chronic administration (18 day) or acute injection of quinolinic acid (QUIN) or vehicle to the striatum contralateral to the preferred limb." | 1.30 | Time-course analysis and comparison of acute and chronic intrastriatal quinolinic acid administration on forelimb reaching deficits in the rat. ( Albin, RL; Bauter, MR; Bazzett, T; Legnard, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mishra, J | 1 |
| Kumar, A | 1 |
| Saliba, SW | 1 |
| Vieira, EL | 1 |
| Santos, RP | 1 |
| Candelario-Jalil, E | 1 |
| Fiebich, BL | 1 |
| Vieira, LB | 1 |
| Teixeira, AL | 1 |
| de Oliveira, AC | 1 |
| Silva-Adaya, D | 1 |
| Pérez-De La Cruz, V | 1 |
| Herrera-Mundo, MN | 1 |
| Mendoza-Macedo, K | 1 |
| Villeda-Hernández, J | 1 |
| Binienda, Z | 1 |
| Ali, SF | 1 |
| Santamaría, A | 1 |
| Burns, LH | 1 |
| Pakzaban, P | 1 |
| Deacon, TW | 1 |
| Brownell, AL | 2 |
| Tatter, SB | 1 |
| Jenkins, BG | 1 |
| Isacson, O | 1 |
| da Cunha, A | 1 |
| Eiden, LE | 1 |
| Rausch, DM | 1 |
| Hantraye, P | 1 |
| Wullner, U | 1 |
| Hamberg, L | 1 |
| Shoup, T | 1 |
| Elmaleh, DR | 1 |
| Frim, DM | 1 |
| Madras, BK | 1 |
| Brownell, GL | 1 |
| Rosen, BR | 1 |
| Bazzett, T | 1 |
| Legnard, E | 1 |
| Bauter, MR | 1 |
| Albin, RL | 1 |
| Engber, TM | 1 |
| Chase, TN | 1 |
| Marrannes, R | 1 |
| Wauquier, A | 1 |
1 review available for quinolinic acid and Movement Disorders
| Article | Year |
|---|---|
Neuronal substrates for SIV encephalopathy.
Topics: Animals; Astrocytes; Cognition Disorders; Disease Progression; Encephalitis, Viral; Gene Expression | 1994 |
8 other studies available for quinolinic acid and Movement Disorders
| Article | Year |
|---|---|
Improvement of mitochondrial function by paliperidone attenuates quinolinic acid-induced behavioural and neurochemical alterations in rats: implications in Huntington's disease.
Topics: Acetylcholinesterase; Animals; Biogenic Amines; Body Weight; Corpus Striatum; Huntington Disease; Is | 2014 |
Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid.
Topics: Animals; Body Weight; Corpus Striatum; Cytokines; Disease Models, Animal; Dose-Response Relationship | 2017 |
Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine.
Topics: Animals; Antioxidants; Brain; Carnitine; Convulsants; Disease Models, Animal; Dose-Response Relation | 2008 |
Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease.
Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Huntington Disease; Macaca mulat | 1995 |
PET- and MRI-based assessment of glucose utilization, dopamine receptor binding, and hemodynamic changes after lesions to the caudate-putamen in primates.
Topics: Acetylcholinesterase; Animals; Apomorphine; Behavior, Animal; Caudate Nucleus; Dopamine; Glucose; He | 1994 |
Time-course analysis and comparison of acute and chronic intrastriatal quinolinic acid administration on forelimb reaching deficits in the rat.
Topics: Animals; Behavior, Animal; Choice Behavior; Conditioning, Operant; Corpus Striatum; Dose-Response Re | 1999 |
Dextromethorphan does not protect against quinolinic acid neurotoxicity in rat striatum.
Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Dextromethorphan; Dibenzocycloheptenes; Dizoc | 1988 |
Episodic barrel rotations induced by intrastriatal injection of quinolinic acid in rats. Inhibition by anticonvulsants.
Topics: Animals; Anticonvulsants; Behavior, Animal; Corpus Striatum; Male; Movement Disorders; Pyridines; Qu | 1988 |