quinolinic acid has been researched along with Learning Disabilities in 4 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study investigated whether the striatal deterioration observed during chronic QA administration produces cognitive impairments in this animal model of HD by testing the effects of chronic administration of QA on spatial learning ability of rats in a radial arm water maze (RAWM) task." | 1.30 | Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task. ( Albin, RL; Bazzett, TJ; Dong, J; Dunbar, GL; Haik-Creguer, KL; Shear, DA, 1998) |
| "The treatment with memantine resulted in steady-state serum levels of 1." | 1.29 | Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine. ( Danysz, W; Frankiewicz, T; Misztal, M; Parsons, CG, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindgren, HS | 1 |
| Wickens, R | 1 |
| Tait, DS | 1 |
| Brown, VJ | 1 |
| Dunnett, SB | 1 |
| McDonald, RJ | 1 |
| King, AL | 1 |
| Foong, N | 1 |
| Rizos, Z | 1 |
| Hong, NS | 1 |
| Misztal, M | 1 |
| Frankiewicz, T | 1 |
| Parsons, CG | 1 |
| Danysz, W | 1 |
| Shear, DA | 1 |
| Dong, J | 1 |
| Haik-Creguer, KL | 1 |
| Bazzett, TJ | 1 |
| Albin, RL | 1 |
| Dunbar, GL | 1 |
4 other studies available for quinolinic acid and Learning Disabilities
| Article | Year |
|---|---|
Lesions of the dorsomedial striatum impair formation of attentional set in rats.
Topics: Animals; Attention; Behavior, Animal; Corpus Striatum; Discrimination Learning; Disease Models, Anim | 2013 |
Neurotoxic lesions of the medial prefrontal cortex or medial striatum impair multiple-location place learning in the water task: evidence for neural structures with complementary roles in behavioural flexibility.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Corpus Striatum; Learning Disabilit | 2008 |
Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine Agents; Hippocampus; Injections, Intrav | 1996 |
Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task.
Topics: Animals; Circadian Rhythm; Corpus Striatum; Functional Laterality; Infusions, Parenteral; Learning D | 1998 |