quinolinic acid has been researched along with Hearing Loss, Sensorineural in 2 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Hearing Loss, Sensorineural: Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors." | 5.29 | Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994) |
| "Our study investigated the neurotoxicity of quinolinic acid (QA) to spiral ganglion cells (SGCs), observed the protective effects of N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 and magnesium ions on the QA-induced injury to SGCs, and analyzed the role of QA in otitis media with effusion (OME)-induced sensorineural hearing loss (SNHL)." | 3.76 | Neurotoxicity of quinolinic acid to spiral ganglion cells in rats. ( He, Y; Xiao, H; Yang, C; Zheng, N, 2010) |
| "Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors." | 1.29 | Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, H | 1 |
| Yang, C | 1 |
| He, Y | 1 |
| Zheng, N | 1 |
| Yellon, RF | 1 |
| Rose, E | 1 |
| Kenna, MA | 1 |
| Doyle, WJ | 1 |
| Casselbrant, M | 1 |
| Diven, WF | 1 |
| Whiteside, TL | 1 |
| Swarts, JD | 1 |
| Heyes, MP | 1 |
2 other studies available for quinolinic acid and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Neurotoxicity of quinolinic acid to spiral ganglion cells in rats.
Topics: Animals; Animals, Newborn; Apoptosis; Calcium; Cells, Cultured; Dizocilpine Maleate; Hearing Loss, S | 2010 |
Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions.
Topics: Animals; Audiometry, Evoked Response; Child; Chinchilla; Cochlea; Gas Chromatography-Mass Spectromet | 1994 |