quinolinic acid has been researched along with Glial Cell Tumors in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid is a product of tryptophan degradation and may serve as a precursor for NAD(+), an important enzymatic cofactor for enzymes such as the DNA repair protein PARP." | 5.39 | The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress. ( Adams, S; Ahrendt, T; Bode, HB; Guillemin, GJ; Oezen, I; Opitz, CA; Platten, M; Radlwimmer, B; Sahm, F; von Deimling, A; Wick, W, 2013) |
| "Quinolinic acid is a product of tryptophan degradation and may serve as a precursor for NAD(+), an important enzymatic cofactor for enzymes such as the DNA repair protein PARP." | 1.39 | The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress. ( Adams, S; Ahrendt, T; Bode, HB; Guillemin, GJ; Oezen, I; Opitz, CA; Platten, M; Radlwimmer, B; Sahm, F; von Deimling, A; Wick, W, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sahm, F | 1 |
| Oezen, I | 1 |
| Opitz, CA | 1 |
| Radlwimmer, B | 1 |
| von Deimling, A | 1 |
| Ahrendt, T | 1 |
| Adams, S | 2 |
| Bode, HB | 1 |
| Guillemin, GJ | 2 |
| Wick, W | 1 |
| Platten, M | 1 |
| Teo, C | 1 |
| McDonald, KL | 1 |
| Zinger, A | 1 |
| Bustamante, S | 1 |
| Lim, CK | 1 |
| Sundaram, G | 1 |
| Braidy, N | 1 |
| Brew, BJ | 1 |
| Ravikumar, A | 1 |
| Deepadevi, KV | 1 |
| Arun, P | 1 |
| Manojkumar, V | 1 |
| Kurup, PA | 1 |
3 other studies available for quinolinic acid and Glial Cell Tumors
| Article | Year |
|---|---|
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neopla | 2013 |
Involvement of the kynurenine pathway in human glioma pathophysiology.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Biosynthetic Pathways; Brain Ne | 2014 |
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythro | 2000 |