quinolinic acid has been researched along with Genetic Predisposition in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We had shown that production of quinolinic acid is high in the brain of epilepsy-prone El mice and that this is due to an increase in the activity of 3-hydroxyanthranilate 3,4-dioxygenase (3-HAO, EC 1." | 3.69 | Increase in the level of mRNA for 3-hydroxyanthranilate 3,4-dioxygenase in brain of epilepsy-prone El mice. ( Asai, H; Kitoh, J; Mori, H; Nakagawa, Y; Nakano, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Graham, RK | 1 |
| Pouladi, MA | 1 |
| Joshi, P | 1 |
| Lu, G | 1 |
| Deng, Y | 1 |
| Wu, NP | 1 |
| Figueroa, BE | 1 |
| Metzler, M | 1 |
| André, VM | 1 |
| Slow, EJ | 1 |
| Raymond, L | 1 |
| Friedlander, R | 1 |
| Levine, MS | 1 |
| Leavitt, BR | 1 |
| Hayden, MR | 1 |
| McLin, JP | 1 |
| Thompson, LM | 1 |
| Steward, O | 1 |
| Nakagawa, Y | 1 |
| Asai, H | 1 |
| Kitoh, J | 1 |
| Mori, H | 1 |
| Nakano, K | 1 |
3 other studies available for quinolinic acid and Genetic Predisposition
| Article | Year |
|---|---|
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease.
Topics: Animals; Brain; Brain Ischemia; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Disease P | 2009 |
Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains.
Topics: Animals; Chimera; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Re | 2006 |
Increase in the level of mRNA for 3-hydroxyanthranilate 3,4-dioxygenase in brain of epilepsy-prone El mice.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Animals; Brain; Dioxygenases; Epilepsy; Genetic Predispositio | 1995 |