Page last updated: 2024-10-20

quinolinic acid and Epilepsies, Myoclonic

quinolinic acid has been researched along with Epilepsies, Myoclonic in 2 studies

Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.

Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martí-Massó, JF1
Bergareche, A1
Makarov, V1
Ruiz-Martinez, J1
Gorostidi, A1
López de Munain, A1
Poza, JJ1
Striano, P1
Buxbaum, JD1
Paisán-Ruiz, C1
Rho, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prednisolone vs. Vigabatrin in the First-line Treatment of Infantile Spasms[NCT02299115]Phase 30 participants (Actual)Interventional2017-09-05Withdrawn (stopped due to Most centres are now using oral steroids as 1st line treatment so question of efficacy is no longer of high interest.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for quinolinic acid and Epilepsies, Myoclonic

ArticleYear
Basic science behind the catastrophic epilepsies.
    Epilepsia, 2004, Volume: 45 Suppl 5

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Corticotropin-Releasing Hormone; Epilepsies

2004

Other Studies

1 other study available for quinolinic acid and Epilepsies, Myoclonic

ArticleYear
The ACMSD gene, involved in tryptophan metabolism, is mutated in a family with cortical myoclonus, epilepsy, and parkinsonism.
    Journal of molecular medicine (Berlin, Germany), 2013, Volume: 91, Issue:12

    Topics: Adult; Aged; Amino Acid Sequence; Brain; Carboxy-Lyases; DNA Mutational Analysis; Electroencephalogr

2013