quinolinic acid has been researched along with Encephalitis, Polio in 4 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spinal cord slices from poliovirus-inoculated macaques in vitro also converted [13C6]L-tryptophan to [13C6]quinolinic acid." | 1.28 | Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain. ( Heyes, MP; Jacobowitz, D; Markey, SP; Saito, K; Takikawa, O; Vickers, JH, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campagnola, G | 1 |
| Gong, P | 1 |
| Peersen, OB | 1 |
| Heyes, MP | 3 |
| Saito, K | 2 |
| Major, EO | 1 |
| Milstien, S | 1 |
| Markey, SP | 2 |
| Vickers, JH | 2 |
| Jacobowitz, D | 1 |
| Takikawa, O | 1 |
1 review available for quinolinic acid and Encephalitis, Polio
| Article | Year |
|---|---|
Quinolinic acid and inflammation.
Topics: Acquired Immunodeficiency Syndrome; Animals; Biomarkers; Brain Ischemia; Disease Models, Animal; HIV | 1993 |
3 other studies available for quinolinic acid and Encephalitis, Polio
| Article | Year |
|---|---|
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
Topics: Allosteric Regulation; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; F | 2011 |
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biopterins; Brain; Encephalitis; Fetus; Indoleamine-Pyrrole 2,3, | 1993 |
Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain.
Topics: Animals; Brain; Enzyme Induction; Immunohistochemistry; Interferon-gamma; Macaca; Poliomyelitis; Pol | 1992 |