quinolinic acid has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid is an endogenous excitotoxin that causes neurotoxicity in diverse areas of the brain and produces motor dysfunction." | 1.36 | Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats. ( Kalonia, H; Kumar, A; Kumar, P; Nehru, B, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castellano-Gonzalez, G | 1 |
| Jacobs, KR | 1 |
| Don, E | 1 |
| Cole, NJ | 1 |
| Adams, S | 1 |
| Lim, CK | 1 |
| Lovejoy, DB | 1 |
| Guillemin, GJ | 1 |
| Zádori, D | 1 |
| Klivényi, P | 1 |
| Vámos, E | 1 |
| Fülöp, F | 1 |
| Toldi, J | 1 |
| Vécsei, L | 1 |
| Kalonia, H | 1 |
| Kumar, P | 1 |
| Kumar, A | 1 |
| Nehru, B | 1 |
1 review available for quinolinic acid and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies.
Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerativ | 2009 |
2 other studies available for quinolinic acid and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.
Topics: Adenosine Triphosphate; Brain; Cell Survival; HEK293 Cells; Humans; Kynurenic Acid; Kynurenine; Kynu | 2019 |
Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats.
Topics: Animals; Ataxia; Body Weight; Cell Survival; Corpus Striatum; Cyclooxygenase 2 Inhibitors; Lactones; | 2010 |