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quinolinic acid and Dyskinesia, Medication-Induced

quinolinic acid has been researched along with Dyskinesia, Medication-Induced in 5 studies

Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.

Research Excerpts

ExcerptRelevanceReference
"Quinolinic acid (QUIN) was used as a typical excitotoxic/pro-oxidant inducer, 3-nitropropionic acid (3-NP) was employed as a mitochondrial function inhibitor, and their combination (QUIN + 3-NP) was also evaluated in in vitro studies."1.36Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine. ( Elinos-Calderón, D; Galván-Arzate, S; Maldonado, PD; Pedraza-Chaverrí, J; Pérez-De La Cruz, V; Robledo-Arratia, Y; Santamaría, A, 2010)
"This relationship is altered in Parkinsonism and in levodopa-induced dyskinesias (LID), resulting in an upregulation of corticostriatal glutamatergic function."1.33Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys. ( Bédard, PJ; Grégoire, L; Guidetti, P; Izzo, E; Rassoulpour, A; Samadi, P; Schwarcz, R, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gago, B1
Marin, C1
Rodríguez-Oroz, MC1
Obeso, JA1
Elinos-Calderón, D1
Robledo-Arratia, Y1
Pérez-De La Cruz, V1
Maldonado, PD1
Galván-Arzate, S1
Pedraza-Chaverrí, J1
Santamaría, A1
Samadi, P2
Grégoire, L2
Rassoulpour, A2
Guidetti, P2
Izzo, E2
Schwarcz, R2
Bédard, PJ2
Di Paolo, T1
Storey, E1
Cipolloni, PB1
Ferrante, RJ1
Kowall, NW1
Beal, MF1

Other Studies

5 other studies available for quinolinic acid and Dyskinesia, Medication-Induced

ArticleYear
l-dopa-induced dyskinesias in unilateral 6-hydroxydopamine-lesioned rats are not modified by excitotoxic lesion of the entopeduncular nucleus and substantia nigra pars reticulata.
    Synapse (New York, N.Y.), 2013, Volume: 67, Issue:7

    Topics: Animals; Antiparkinson Agents; Dyskinesia, Drug-Induced; Entopeduncular Nucleus; Levodopa; Male; Mov

2013
Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:1

    Topics: Animals; Antioxidants; Brain; Corpus Striatum; Cysteine; Disease Models, Animal; Dyskinesia, Drug-In

2010
Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:7

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dose-

2005
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys.
    Behavioural brain research, 2008, Jan-25, Volume: 186, Issue:2

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Drug Interactions; Dyskines

2008
Movement disorder following excitotoxin lesions in primates.
    Neuroreport, 1994, Jun-02, Volume: 5, Issue:10

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dyskinesia, Drug-I

1994