quinolinic acid has been researched along with Diathesis in 4 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A transgenic mouse model of Huntington's disease (R6/1 and R6/2 lines) expressing exon 1 of the HD gene with 115-150 CAG repeats resisted striatal damage following injection of quinolinic acid and other neurotoxins." | 1.31 | Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease. ( Aronin, N; Brundin, P; Chase, K; DiFiglia, M; Petersén, A; Puschban, Z, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, ZQ | 1 |
| Wang, XX | 1 |
| Wang, Y | 1 |
| Chuang, DM | 1 |
| DiFiglia, M | 2 |
| Chase, TN | 1 |
| Qin, ZH | 1 |
| McLin, JP | 1 |
| Thompson, LM | 1 |
| Lusis, AJ | 1 |
| Davis, RC | 1 |
| Steward, O | 1 |
| Petersén, A | 1 |
| Chase, K | 1 |
| Puschban, Z | 1 |
| Brundin, P | 1 |
| Aronin, N | 1 |
| Finn, SF | 1 |
| Hyman, BT | 1 |
| Storey, E | 1 |
| Miller, JM | 1 |
| Beal, MF | 1 |
4 other studies available for quinolinic acid and Diathesis
| Article | Year |
|---|---|
Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity.
Topics: Adult; Aged, 80 and over; Animals; Calbindins; Choline O-Acetyltransferase; Corpus Striatum; Disease | 2005 |
Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid.
Topics: Animals; Chromosomes, Mammalian; Corpus Striatum; Disease Susceptibility; Excitatory Amino Acid Agon | 2008 |
Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease.
Topics: Animals; Cell Count; Cell Death; Corpus Striatum; Disease Models, Animal; Disease Susceptibility; He | 2002 |
Effects of aging on quinolinic acid lesions in rat striatum.
Topics: Aging; Animals; Biomarkers; Cerebral Cortex; Corpus Striatum; Disease Susceptibility; Hippocampus; M | 1991 |