quinolinic acid has been researched along with Crohn Disease in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both the Crohn's disease exclusion diet combined with partial enteral nutrition (CDED+PEN) and exclusive enteral nutrition (EEN) can induce remission in mild-to-moderate pediatric Crohn's disease and are associated with a marked decrease in fecal kynurenine levels." | 3.30 | Sustained Diet-Induced Remission in Pediatric Crohn's Disease Is Associated With Kynurenine and Serotonin Pathways. ( Benninga, MA; Boneh, RS; de Jonge, WJ; Emond, P; Ghiboub, M; Lefèvre, A; Sovran, B; Van Limbergen, JE; Verburgt, CM; Wine, E, 2023) |
| "Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) characterized by variable phenotypes." | 1.40 | Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases. ( Bustamante, S; Campbell, B; Hejazi, L; Leong, RW; Pickford, R; Shin, S; Wasinger, VC; Yau, YY, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ghiboub, M | 1 |
| Boneh, RS | 1 |
| Sovran, B | 1 |
| Wine, E | 1 |
| Lefèvre, A | 1 |
| Emond, P | 1 |
| Verburgt, CM | 1 |
| Benninga, MA | 1 |
| de Jonge, WJ | 1 |
| Van Limbergen, JE | 1 |
| Nikolaus, S | 1 |
| Schulte, B | 1 |
| Al-Massad, N | 1 |
| Thieme, F | 1 |
| Schulte, DM | 1 |
| Bethge, J | 1 |
| Rehman, A | 1 |
| Tran, F | 1 |
| Aden, K | 1 |
| Häsler, R | 1 |
| Moll, N | 1 |
| Schütze, G | 1 |
| Schwarz, MJ | 1 |
| Waetzig, GH | 1 |
| Rosenstiel, P | 1 |
| Krawczak, M | 1 |
| Szymczak, S | 1 |
| Schreiber, S | 1 |
| Yau, YY | 1 |
| Leong, RW | 1 |
| Shin, S | 1 |
| Bustamante, S | 1 |
| Pickford, R | 1 |
| Hejazi, L | 1 |
| Campbell, B | 1 |
| Wasinger, VC | 1 |
1 trial available for quinolinic acid and Crohn Disease
| Article | Year |
|---|---|
Sustained Diet-Induced Remission in Pediatric Crohn's Disease Is Associated With Kynurenine and Serotonin Pathways.
Topics: Child; Crohn Disease; Diet; Humans; Kynurenine; Melatonin; Prospective Studies; Quinolinic Acid; Rem | 2023 |
2 other studies available for quinolinic acid and Crohn Disease
| Article | Year |
|---|---|
Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Transport Systems, Neutral; Biomarkers; Biotr | 2017 |
Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases.
Topics: Adult; Angiotensin II; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Female; G(M3) Gangl | 2014 |