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quinolinic acid and Cognition Disorders

quinolinic acid has been researched along with Cognition Disorders in 9 studies

Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Aim & Objective: To delineate the associations between executive impairments and changes in tryptophan catabolite (TRYCAT) patterning, negative symptoms and deficit schizophrenia."7.88The Effects of Tryptophan Catabolites on Negative Symptoms and Deficit Schizophrenia are Partly Mediated by Executive Impairments: Results of Partial Least Squares Path Modeling. ( Kanchanatawan, B; Maes, M, 2018)
"Aim & Objective: To delineate the associations between executive impairments and changes in tryptophan catabolite (TRYCAT) patterning, negative symptoms and deficit schizophrenia."3.88The Effects of Tryptophan Catabolites on Negative Symptoms and Deficit Schizophrenia are Partly Mediated by Executive Impairments: Results of Partial Least Squares Path Modeling. ( Kanchanatawan, B; Maes, M, 2018)
" Low xanthurenic acid occurred in both AD and with aging."3.85Kynurenine Pathway Metabolites in Alzheimer's Disease. ( Advani, R; Giil, LM; Midttun, Ø; Refsum, H; Smith, AD; Ueland, PM; Ulvik, A, 2017)
"These are astrocytosis, up-regulation of mRNA encoding the neuropeptide somatostatin (SRIF) and an increased expression of MHC Class II antigen."2.39Neuronal substrates for SIV encephalopathy. ( da Cunha, A; Eiden, LE; Rausch, DM, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giil, LM1
Midttun, Ø1
Refsum, H1
Ulvik, A1
Advani, R1
Smith, AD1
Ueland, PM1
Kanchanatawan, B1
Maes, M1
Croxson, PL1
Walton, ME1
Boorman, ED1
Rushworth, MF1
Bannerman, DM1
Kandanearatchi, A1
Brew, BJ1
Schwarz, MJ1
Guillemin, GJ1
Teipel, SJ1
Buerger, K1
Hampel, H1
da Cunha, A1
Eiden, LE2
Rausch, DM2
Heyes, MP1
Murray, EA1
Lendvay, J1
Sharer, LR1
Ward, JM1
Rehm, S1
Nohr, D1
Weihe, E1
O'Neill, AB1
Morgan, SJ1
Brioni, JD1
Schuster, GM1
Schmidt, WJ1

Reviews

2 reviews available for quinolinic acid and Cognition Disorders

ArticleYear
The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders.
    The FEBS journal, 2012, Volume: 279, Issue:8

    Topics: Central Nervous System Diseases; Cognition Disorders; HIV; HIV Infections; Humans; Kynurenine; Quino

2012
Neuronal substrates for SIV encephalopathy.
    Advances in neuroimmunology, 1994, Volume: 4, Issue:3

    Topics: Animals; Astrocytes; Cognition Disorders; Disease Progression; Encephalitis, Viral; Gene Expression

1994

Other Studies

7 other studies available for quinolinic acid and Cognition Disorders

ArticleYear
Kynurenine Pathway Metabolites in Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 60, Issue:2

    Topics: 3-Hydroxyanthranilic Acid; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; C

2017
The Effects of Tryptophan Catabolites on Negative Symptoms and Deficit Schizophrenia are Partly Mediated by Executive Impairments: Results of Partial Least Squares Path Modeling.
    CNS & neurological disorders drug targets, 2018, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Cognition Disorders; Executive Function; Female; Huma

2018
Unilateral medial frontal cortex lesions cause a cognitive decision-making deficit in rats.
    The European journal of neuroscience, 2014, Volume: 40, Issue:12

    Topics: Animals; Cognition Disorders; Decision Making; Dopamine; Frontal Lobe; Functional Laterality; Male;

2014
Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls.
    European archives of psychiatry and clinical neuroscience, 2013, Volume: 263, Issue:4

    Topics: Aged; Alzheimer Disease; Biomarkers; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pres

2013
Cytopathologic and neurochemical correlates of progression to motor/cognitive impairment in SIV-infected rhesus monkeys.
    Journal of neuropathology and experimental neurology, 1994, Volume: 53, Issue:2

    Topics: Animals; Brain; Cerebral Cortex; Cognition; Cognition Disorders; Glial Fibrillary Acidic Protein; Ma

1994
Histological and behavioral protection by (-)-nicotine against quinolinic acid-induced neurodegeneration in the hippocampus.
    Neurobiology of learning and memory, 1998, Volume: 69, Issue:1

    Topics: Animals; Brain Diseases; Cognition Disorders; Hippocampus; Male; Maze Learning; Memory Disorders; Ne

1998
D-cycloserine reverses the working memory impairment of hippocampal-lesioned rats in a spatial learning task.
    European journal of pharmacology, 1992, Nov-24, Volume: 224, Issue:1

    Topics: Analysis of Variance; Animals; Cognition Disorders; Cycloserine; Hippocampus; Male; Memory Disorders

1992