quinolinic acid has been researched along with Cochlear Hearing Loss in 2 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Excerpt | Relevance | Reference |
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"Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors." | 5.29 | Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994) |
"Our study investigated the neurotoxicity of quinolinic acid (QA) to spiral ganglion cells (SGCs), observed the protective effects of N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 and magnesium ions on the QA-induced injury to SGCs, and analyzed the role of QA in otitis media with effusion (OME)-induced sensorineural hearing loss (SNHL)." | 3.76 | Neurotoxicity of quinolinic acid to spiral ganglion cells in rats. ( He, Y; Xiao, H; Yang, C; Zheng, N, 2010) |
"Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors." | 1.29 | Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Xiao, H | 1 |
Yang, C | 1 |
He, Y | 1 |
Zheng, N | 1 |
Yellon, RF | 1 |
Rose, E | 1 |
Kenna, MA | 1 |
Doyle, WJ | 1 |
Casselbrant, M | 1 |
Diven, WF | 1 |
Whiteside, TL | 1 |
Swarts, JD | 1 |
Heyes, MP | 1 |
2 other studies available for quinolinic acid and Cochlear Hearing Loss
Article | Year |
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Neurotoxicity of quinolinic acid to spiral ganglion cells in rats.
Topics: Animals; Animals, Newborn; Apoptosis; Calcium; Cells, Cultured; Dizocilpine Maleate; Hearing Loss, S | 2010 |
Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions.
Topics: Animals; Audiometry, Evoked Response; Child; Chinchilla; Cochlea; Gas Chromatography-Mass Spectromet | 1994 |