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quinolinic acid and Cochlear Hearing Loss

quinolinic acid has been researched along with Cochlear Hearing Loss in 2 studies

Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.

Research Excerpts

ExcerptRelevanceReference
"Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors."5.29Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994)
"Our study investigated the neurotoxicity of quinolinic acid (QA) to spiral ganglion cells (SGCs), observed the protective effects of N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 and magnesium ions on the QA-induced injury to SGCs, and analyzed the role of QA in otitis media with effusion (OME)-induced sensorineural hearing loss (SNHL)."3.76Neurotoxicity of quinolinic acid to spiral ganglion cells in rats. ( He, Y; Xiao, H; Yang, C; Zheng, N, 2010)
"Quinolinic acid (QUIN) is an endogenous metabolite that exerts a neurotoxic effect by binding to specific neuronal receptors."1.29Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. ( Casselbrant, M; Diven, WF; Doyle, WJ; Heyes, MP; Kenna, MA; Rose, E; Swarts, JD; Whiteside, TL; Yellon, RF, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xiao, H1
Yang, C1
He, Y1
Zheng, N1
Yellon, RF1
Rose, E1
Kenna, MA1
Doyle, WJ1
Casselbrant, M1
Diven, WF1
Whiteside, TL1
Swarts, JD1
Heyes, MP1

Other Studies

2 other studies available for quinolinic acid and Cochlear Hearing Loss

ArticleYear
Neurotoxicity of quinolinic acid to spiral ganglion cells in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2010, Volume: 30, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Calcium; Cells, Cultured; Dizocilpine Maleate; Hearing Loss, S

2010
Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions.
    The Laryngoscope, 1994, Volume: 104, Issue:2

    Topics: Animals; Audiometry, Evoked Response; Child; Chinchilla; Cochlea; Gas Chromatography-Mass Spectromet

1994