quinolinic acid has been researched along with Chronic Kidney Failure in 8 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QA) is a potent endogenous excitotoxin; elevation of its concentration in an organism has been implicated in the pathogenesis of various disorders." | 5.32 | Contribution of quinolinic acid in the development of anemia in renal insufficiency. ( Buczko, W; Koda, M; Pawlak, D; Pawlak, S; Wolczynski, S, 2003) |
| "Increased oxidative stress (SOX), inflammation and accelerated atherosclerosis have been reported in end-stage renal disease (ESRD), but their associations with kynurenine pathway activation remain unknown." | 3.75 | Kynurenine, quinolinic acid--the new factors linked to carotid atherosclerosis in patients with end-stage renal disease. ( Brzosko, S; Mysliwiec, M; Pawlak, D; Pawlak, K, 2009) |
| "Quinolinic acid (QA) is a potent endogenous excitotoxin; elevation of its concentration in an organism has been implicated in the pathogenesis of various disorders." | 1.32 | Contribution of quinolinic acid in the development of anemia in renal insufficiency. ( Buczko, W; Koda, M; Pawlak, D; Pawlak, S; Wolczynski, S, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pawlak, K | 2 |
| Brzosko, S | 1 |
| Mysliwiec, M | 2 |
| Pawlak, D | 6 |
| Schefold, JC | 1 |
| Zeden, JP | 1 |
| Fotopoulou, C | 1 |
| von Haehling, S | 1 |
| Pschowski, R | 1 |
| Hasper, D | 1 |
| Volk, HD | 1 |
| Schuett, C | 1 |
| Reinke, P | 1 |
| Myśliwiec, P | 3 |
| Myśliwiec, H | 1 |
| Dadan, J | 1 |
| Buczko, W | 5 |
| Koda, M | 1 |
| Pawlak, S | 1 |
| Wolczynski, S | 1 |
| Tankiewicz, A | 2 |
| Koide, K | 1 |
| Toyama, J | 1 |
| Inoue, N | 1 |
| Koshikawa, S | 1 |
| Akizawa, T | 1 |
| Takahashi, K | 1 |
| Hidaka, S | 1 |
| Yamane, Y | 1 |
| Shinoda, K | 1 |
| Nakao, M | 1 |
8 other studies available for quinolinic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
Kynurenine, quinolinic acid--the new factors linked to carotid atherosclerosis in patients with end-stage renal disease.
Topics: Adult; Age Factors; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Cross-Sectional Studies | 2009 |
Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.
Topics: 5-Hydroxytryptophan; Adult; Aged; C-Reactive Protein; Case-Control Studies; Creatinine; Female; Huma | 2009 |
[Tryptophan and its metabolites in renal allograft recipients].
Topics: Adult; Aged; Creatinine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Kynurenine | 2009 |
Contribution of quinolinic acid in the development of anemia in renal insufficiency.
Topics: Anemia; Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Survival; Cobalt; Disease Models, Ani | 2003 |
Kynurenine and its metabolites in the rat with experimental renal insufficiency.
Topics: Animals; Drinking; Eating; Kidney Failure, Chronic; Kynurenine; Male; Quinolinic Acid; Rats; Rats, W | 2001 |
Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure.
Topics: Animals; Chromatography, High Pressure Liquid; Creatinine; Kidney; Kidney Failure, Chronic; Kynureni | 2002 |
Endogenous neurotoxine-quinolinic acid is increased in renal allograft recipients.
Topics: Adult; Aged; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Neu | 2002 |
[Uremic peak 2a in high performance liquid chromatography--acidic components and their membrane permeability].
Topics: Cell Membrane Permeability; Chromatography, High Pressure Liquid; Glutamine; Humans; Kidney Failure, | 1986 |