quinolinic acid has been researched along with Brain Neoplasms in 6 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There has been considerable scientific effort dedicated to understanding the biologic consequence and therapeutic implications of aberrant tryptophan metabolism in brain tumors and neurodegenerative diseases." | 4.31 | Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARĪ³ signaling axis. ( Buelow, KL; Chinnaiyan, P; Kant, S; Kesarwani, P; Miller, CR; Prabhu, A; Zhao, Y, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kesarwani, P | 1 |
| Kant, S | 1 |
| Zhao, Y | 1 |
| Prabhu, A | 1 |
| Buelow, KL | 1 |
| Miller, CR | 1 |
| Chinnaiyan, P | 1 |
| Adams, S | 1 |
| Teo, C | 1 |
| McDonald, KL | 1 |
| Zinger, A | 1 |
| Bustamante, S | 1 |
| Lim, CK | 1 |
| Sundaram, G | 1 |
| Braidy, N | 1 |
| Brew, BJ | 1 |
| Guillemin, GJ | 1 |
| Wszelaki, N | 1 |
| Melzig, MF | 1 |
| Moffett, JR | 1 |
| Els, T | 1 |
| Espey, MG | 1 |
| Walter, SA | 1 |
| Streit, WJ | 1 |
| Namboodiri, MA | 1 |
| Ravikumar, A | 1 |
| Deepadevi, KV | 1 |
| Arun, P | 1 |
| Manojkumar, V | 1 |
| Kurup, PA | 1 |
| Vezzani, A | 1 |
| Gramsbergen, JB | 1 |
| Speciale, C | 1 |
| Schwarcz, R | 1 |
6 other studies available for quinolinic acid and Brain Neoplasms
| Article | Year |
|---|---|
Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARĪ³ signaling axis.
Topics: Animals; Biological Products; Brain Neoplasms; Glioblastoma; Immune Tolerance; Macrophages; Mice; Ne | 2023 |
Involvement of the kynurenine pathway in human glioma pathophysiology.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Biosynthetic Pathways; Brain Ne | 2014 |
Research on an in vitro cell system for testing the neurotoxicity of kynurenine pathway metabolites.
Topics: Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Survival; Coloring Agents; Fluorescent | 2011 |
Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes.
Topics: Animals; Antibody Specificity; Astrocytes; Biomarkers; Brain Neoplasms; Corpus Striatum; Female; Gli | 1997 |
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythro | 2000 |
Production of quinolinic acid and kynurenic acid by human glioma.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Astrocytoma; Brain Neoplasms; Diox | 1991 |