quinolinic acid and Benign Psychomotor Epilepsy, Childhood
quinolinic acid has been researched along with Benign Psychomotor Epilepsy, Childhood in 6 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 5.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
"Spontaneous recurrent seizures induced by pilocarpine were monitored behaviorally prior to and after PING or under control conditions." | 1.62 | Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy. ( Bertram, EH; Buckmaster, PS; Ghobadi, SN; Habte, FG; Hou, Q; Huang, A; Keunen, O; Lee, KS; Li, N; Narang, S; Qiu, L; Wang, J; Wintermark, M; Zhang, Y, 2021) |
"Quinolinic acid was not detected in the brain of patients who received antiepileptic drugs other than carbamazepine prior to surgery or in brain endothelial cultures obtained from a control patient." | 1.38 | A pro-convulsive carbamazepine metabolite: quinolinic acid in drug resistant epileptic human brain. ( Alexopoulos, AV; Ghosh, C; Gonzalez-Martinez, J; Hossain, M; Janigro, D; Marchi, N; Rasmussen, P; Yang, H, 2012) |
"QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 1.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
Research
Studies (6)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (50.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors
Authors | Studies |
---|---|
Zhang, Y | 1 |
Buckmaster, PS | 1 |
Qiu, L | 1 |
Wang, J | 1 |
Keunen, O | 1 |
Ghobadi, SN | 1 |
Huang, A | 1 |
Hou, Q | 1 |
Li, N | 1 |
Narang, S | 1 |
Habte, FG | 1 |
Bertram, EH | 1 |
Lee, KS | 1 |
Wintermark, M | 1 |
Ghosh, C | 1 |
Marchi, N | 1 |
Hossain, M | 1 |
Rasmussen, P | 1 |
Alexopoulos, AV | 1 |
Gonzalez-Martinez, J | 1 |
Yang, H | 1 |
Janigro, D | 1 |
Schwarcz, R | 3 |
Köhler, C | 2 |
Foster, AC | 1 |
French, ED | 1 |
Whetsell, WO | 1 |
Du, F | 1 |
Vezzani, A | 1 |
Wu, HQ | 1 |
Tullii, M | 1 |
Samanin, R | 1 |
Reviews
1 review available for quinolinic acid and Benign Psychomotor Epilepsy, Childhood
Article | Year |
---|---|
Quinolinic acid and kynurenic acid in the mammalian brain.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; AIDS Dementia Complex; Animals; Aspartic Acid; Biological Tra | 1991 |
Other Studies
5 other studies available for quinolinic acid and Benign Psychomotor Epilepsy, Childhood
Article | Year |
---|---|
Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Epilepsy, Temporal Lobe; Intraoperative Neurop | 2021 |
A pro-convulsive carbamazepine metabolite: quinolinic acid in drug resistant epileptic human brain.
Topics: Adult; Anticonvulsants; Biotransformation; Brain Chemistry; Carbamazepine; Child; Chromatography, Hi | 2012 |
Differential vulnerability of central neurons of the rat to quinolinic acid.
Topics: Animals; Brain; Corpus Striatum; Diencephalon; Epilepsy, Temporal Lobe; Hippocampus; Huntington Dise | 1983 |
Excitotoxic models for neurodegenerative disorders.
Topics: Amino Acids; Animals; Axons; Dendrites; Epilepsy, Temporal Lobe; Hippocampus; Humans; Ibotenic Acid; | 1984 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, | 1986 |