quinolinic acid has been researched along with Autosomal Dominant Striatonigral Degeneration in 1 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This abnormal proteolysis leads to the accumulation of cleaved fragments, which have been identified as toxic and further they act as a seed for more aggregate formation, thereby increasing toxicity in neuronal cells." | 1.46 | n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3. ( Chiang, IT; Chiou, TW; Harn, HJ; Hsieh, DK; Lin, SY; Lin, SZ; Liu, JW; Rajamani, K; Wu, CH; You, DH, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rajamani, K | 1 |
| Liu, JW | 1 |
| Wu, CH | 1 |
| Chiang, IT | 1 |
| You, DH | 1 |
| Lin, SY | 1 |
| Hsieh, DK | 1 |
| Lin, SZ | 1 |
| Harn, HJ | 1 |
| Chiou, TW | 1 |
1 other study available for quinolinic acid and Autosomal Dominant Striatonigral Degeneration
| Article | Year |
|---|---|
n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3.
Topics: Animals; Ataxin-3; Calcium; Calpain; Cerebellum; Disease Models, Animal; HEK293 Cells; Humans; Macha | 2017 |