quinolinic acid has been researched along with Autism Spectrum Disorder in 4 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yildirim, V | 1 |
| Simsek, S | 1 |
| Cetin, I | 1 |
| Dokuyucu, R | 1 |
| Bryn, V | 2 |
| Verkerk, R | 2 |
| Skjeldal, OH | 2 |
| Saugstad, OD | 2 |
| Ormstad, H | 2 |
| Halvorsen, B | 1 |
| Isaksen, J | 1 |
| Maes, M | 1 |
| Gevi, F | 1 |
| Zolla, L | 1 |
| Gabriele, S | 1 |
| Persico, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gut Mobilization With Oral Administration of Polyethylene Glycol (PEG) at the Dose of 6.9 g/d Once a Day for 6 Months in Chronically Constipated Autistic Children.[NCT05025553] | 21 participants (Actual) | Interventional | 2018-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for quinolinic acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
Kynurenine, Kynurenic Acid, Quinolinic Acid and Interleukin-6 Levels in the Serum of Patients with Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Child; Child, Preschool; Humans; Infant; Interleukin-6; Kynurenic Acid; Ky | 2023 |
Kynurenine Pathway in Autism Spectrum Disorders in Children.
Topics: Autism Spectrum Disorder; Biomarkers; Child; Chromatography, High Pressure Liquid; Comorbidity; Fema | 2017 |
Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders.
Topics: 5-Hydroxytryptophan; Adolescent; Analysis of Variance; Autism Spectrum Disorder; Brain-Derived Neuro | 2018 |
Urinary metabolomics of young Italian autistic children supports abnormal tryptophan and purine metabolism.
Topics: Autism Spectrum Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Chromatography, | 2016 |