quinolinic acid has been researched along with Amino Acid Metabolism Disorders, Inborn in 6 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QUIN) is an agonist of the neurotransmitter glutamate (Glu) capable of binding to N-methyl-D-aspartate receptors (NMDAR) increasing glutamatergic signaling." | 1.62 | Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamatergic disorders. ( Antunes Soares, FA; Aschner, M; Bicca Obetine Baptista, F; Duarte Hartmann, D; Farina Gonçalves, D; Franzen da Silva, A; Lenz Dalla Corte, C; Limana da Silveira, T; Lopes Machado, M; Marafiga Cordeiro, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Barbieri Caus, L | 1 |
| Pasquetti, MV | 1 |
| Seminotti, B | 3 |
| Woontner, M | 1 |
| Wajner, M | 3 |
| Calcagnotto, ME | 1 |
| Limana da Silveira, T | 1 |
| Lopes Machado, M | 1 |
| Bicca Obetine Baptista, F | 1 |
| Farina Gonçalves, D | 1 |
| Duarte Hartmann, D | 1 |
| Marafiga Cordeiro, L | 1 |
| Franzen da Silva, A | 1 |
| Lenz Dalla Corte, C | 1 |
| Aschner, M | 1 |
| Antunes Soares, FA | 1 |
| Amaral, AU | 1 |
| da Silva, JC | 1 |
| de Oliveira, FH | 1 |
| Ribeiro, RT | 1 |
| Vargas, CR | 1 |
| Leipnitz, G | 2 |
| Santamaría, A | 2 |
| Souza, DO | 2 |
| Colín-González, AL | 1 |
| Paz-Loyola, AL | 1 |
| Serratos, I | 1 |
| Ribeiro, CA | 1 |
| Goodman, SI | 1 |
| Land, JM | 1 |
| Goulder, P | 1 |
| Johnson, A | 1 |
| Hockaday, J | 1 |
6 other studies available for quinolinic acid and Amino Acid Metabolism Disorders, Inborn
| Article | Year |
|---|---|
Increased susceptibility to quinolinic acid-induced seizures and long-term changes in brain oscillations in an animal model of glutaric acidemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Disease Models, Ani | 2022 |
Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamatergic disorders.
Topics: 1-Octanol; Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Animals, Genetical | 2021 |
Induction of Neuroinflammatory Response and Histopathological Alterations Caused by Quinolinic Acid Administration in the Striatum of Glutaryl-CoA Dehydrogenase Deficient Mice.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; CD3 Complex; Corpus Striat | 2018 |
Toxic synergism between quinolinic acid and organic acids accumulating in glutaric acidemia type I and in disorders of propionate metabolism in rat brain synaptosomes: Relevance for metabolic acidemias.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Brain Diseases, Metabolic; Disease Models, Ani | 2015 |
Development of pathogenic concepts in glutaryl-CoA dehydrogenase deficiency: the challenge.
Topics: Amino Acid Metabolism, Inborn Errors; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Oxidoreductase | 2004 |
Glutaric aciduria type 1 an atypical presentation together with some observations upon treatment and the possible cause of cerebral damage.
Topics: Amino Acid Metabolism, Inborn Errors; Aminocaproates; Brain; Glutarates; Humans; Infant; Quinolinic | 1992 |