quinolinic acid has been researched along with Allergic Encephalomyelitis in 3 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The excitotoxin quinolinic acid, a by-product of the kynurenine pathway, is known to be involved in several neurological diseases including multiple sclerosis (MS)." | 7.80 | Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies. ( Adams, S; Brew, BJ; Guillemin, GJ; Jones, SP; Lim, CK; Sundaram, G, 2014) |
| "Quinolinic acid (QUIN) is a neurotoxin and endogenous N-methyl-D-aspartate receptor agonist formed from tryptophan." | 5.29 | Neurotoxin quinolinic acid is selectively elevated in spinal cords of rats with experimental allergic encephalomyelitis. ( Chang, SY; Erickson, JB; Flanagan, EM; Reinhard, JF; Viveros, OH, 1995) |
| " Evidence has suggested that the activation of indoleamine-2,3-dioxygenase (IDO), the rate-limiting enzyme in the kynurenine pathway (KP), plays a crucial role in inflammation-related diseases." | 3.96 | Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice. ( Boeira, SP; Cattelan Souza, L; Giacomeli, R; Jesse, CR; Prigol, M; Silva, MRP; Zarzecki, MS, 2020) |
| "The excitotoxin quinolinic acid, a by-product of the kynurenine pathway, is known to be involved in several neurological diseases including multiple sclerosis (MS)." | 3.80 | Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies. ( Adams, S; Brew, BJ; Guillemin, GJ; Jones, SP; Lim, CK; Sundaram, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zarzecki, MS | 1 |
| Cattelan Souza, L | 1 |
| Giacomeli, R | 1 |
| Silva, MRP | 1 |
| Prigol, M | 1 |
| Boeira, SP | 1 |
| Jesse, CR | 1 |
| Sundaram, G | 1 |
| Brew, BJ | 1 |
| Jones, SP | 1 |
| Adams, S | 1 |
| Lim, CK | 1 |
| Guillemin, GJ | 1 |
| Flanagan, EM | 1 |
| Erickson, JB | 1 |
| Viveros, OH | 1 |
| Chang, SY | 1 |
| Reinhard, JF | 1 |
3 other studies available for quinolinic acid and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice.
Topics: Animals; Body Weight; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Fem | 2020 |
Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cell Line, Transformed; Encephalomyelitis, Autoimmune, E | 2014 |
Neurotoxin quinolinic acid is selectively elevated in spinal cords of rats with experimental allergic encephalomyelitis.
Topics: Animals; Dexamethasone; Encephalomyelitis, Autoimmune, Experimental; Male; Quinolinic Acid; Rats; Ra | 1995 |