quinolinic acid has been researched along with Age-Related Memory Disorders in 13 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid (QA) is an N-methyl-d-aspartate agonist that has been shown to produce neurotoxic effects that mimic certain neurodegenerative diseases when administered to laboratory animals." | 1.31 | Quinolinic acid released from polymeric brain implants causes behavioral and neuroanatomical alterations in a rodent model of Huntington's disease. ( Dunbar, GL; Haik, KL; Sabel, BA; Schroeder, U; Shear, DA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar Arora, M | 1 |
| Ratra, A | 1 |
| Asdaq, SMB | 1 |
| Alshamrani, AA | 1 |
| Alsalman, AJ | 1 |
| Kamal, M | 1 |
| Tomar, R | 1 |
| Sahoo, J | 1 |
| Ashok, J | 1 |
| Imran, M | 1 |
| Anderson, AM | 1 |
| Croteau, D | 1 |
| Ellis, RJ | 1 |
| Rosario, D | 1 |
| Potter, M | 1 |
| Guillemin, GJ | 1 |
| Brew, BJ | 1 |
| Woods, SP | 1 |
| Letendre, SL | 1 |
| Rahman, A | 1 |
| Rao, MS | 1 |
| Khan, KM | 1 |
| Mishra, J | 1 |
| Kumar, A | 1 |
| Velloso, NA | 1 |
| Dalmolin, GD | 1 |
| Gomes, GM | 1 |
| Rubin, MA | 1 |
| Canas, PM | 1 |
| Cunha, RA | 1 |
| Mello, CF | 1 |
| Flavell, CR | 1 |
| Lee, JL | 1 |
| Dairam, A | 1 |
| Müller, AC | 1 |
| Daya, S | 1 |
| Beninger, RJ | 1 |
| Wirsching, BA | 1 |
| Mallet, PE | 1 |
| Jhamandas, K | 1 |
| Boegman, RJ | 1 |
| Misztal, M | 1 |
| Skangiel-Kramska, J | 1 |
| Niewiadomska, G | 1 |
| Danysz, W | 1 |
| Dias, R | 1 |
| Robbins, TW | 1 |
| Roberts, AC | 1 |
| O'Neill, AB | 1 |
| Morgan, SJ | 1 |
| Brioni, JD | 1 |
| Haik, KL | 1 |
| Shear, DA | 1 |
| Schroeder, U | 1 |
| Sabel, BA | 1 |
| Dunbar, GL | 1 |
| Schuster, GM | 1 |
| Schmidt, WJ | 1 |
13 other studies available for quinolinic acid and Age-Related Memory Disorders
| Article | Year |
|---|---|
Plumbagin Alleviates Intracerebroventricular-Quinolinic Acid Induced Depression-like Behavior and Memory Deficits in Wistar Rats.
Topics: Animals; Behavior, Animal; Depression; Male; Memory Disorders; Naphthoquinones; Oxidative Stress; Qu | 2022 |
HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau.
Topics: Adult; AIDS Dementia Complex; Biomarkers; Female; Humans; Male; Memory Disorders; Memory, Episodic; | 2018 |
Intraventricular infusion of quinolinic acid impairs spatial learning and memory in young rats: a novel mechanism of lead-induced neurotoxicity.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; CREB-Binding Protein; Disease Models, Animal | 2018 |
Improvement of mitochondrial function by paliperidone attenuates quinolinic acid-induced behavioural and neurochemical alterations in rats: implications in Huntington's disease.
Topics: Acetylcholinesterase; Animals; Biogenic Amines; Body Weight; Corpus Striatum; Huntington Disease; Is | 2014 |
Spermine improves recognition memory deficit in a rodent model of Huntington's disease.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory | 2009 |
Post-training unilateral amygdala lesions selectively impair contextual fear memories.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Conditioning, Classical; Electroshock | 2012 |
Non-steroidal anti-inflammatory agents, tolmetin and sulindac attenuate quinolinic acid (QA)-induced oxidative stress in primary hippocampal neurons and reduce QA-induced spatial reference memory deficits in male Wistar rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Female; Glutathion | 2007 |
Physostigmine, but not 3,4-diaminopyridine, improves radial maze performance in memory-impaired rats.
Topics: 4-Aminopyridine; Amifampridine; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Dose-Response | 1995 |
Subchronic intraventricular infusion of quinolinic acid produces working memory impairment--a model of progressive excitotoxicity.
Topics: Alzheimer Disease; Animals; Cerebral Ventricles; Disease Models, Animal; Disease Progression; Drug A | 1996 |
Dissociable forms of inhibitory control within prefrontal cortex with an analog of the Wisconsin Card Sort Test: restriction to novel situations and independence from "on-line" processing.
Topics: Animals; Attention; Callithrix; Discrimination, Psychological; Female; Male; Memory; Memory Disorder | 1997 |
Histological and behavioral protection by (-)-nicotine against quinolinic acid-induced neurodegeneration in the hippocampus.
Topics: Animals; Brain Diseases; Cognition Disorders; Hippocampus; Male; Maze Learning; Memory Disorders; Ne | 1998 |
Quinolinic acid released from polymeric brain implants causes behavioral and neuroanatomical alterations in a rodent model of Huntington's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Huntington Disease; Implants, Experimental; Male; | 2000 |
D-cycloserine reverses the working memory impairment of hippocampal-lesioned rats in a spatial learning task.
Topics: Analysis of Variance; Animals; Cognition Disorders; Cycloserine; Hippocampus; Male; Memory Disorders | 1992 |